ONTOLOGY REPORT - ANNOTATIONS


Term:synapse maturation
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Accession:GO:0060074 term browser browse the term
Definition:The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.
Synonyms:exact_synonym: synaptic maturation


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synapse maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 13 74,154,533 74,333,244 RGD:1624291
G Bcan brevican JBrowse link 2 187,359,674 187,373,133 RGD:1600115
RGD:1624291
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:1600115
RGD:1624291
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:2289990
G Igsf21 immunoglobin superfamily, member 21 JBrowse link 5 158,503,090 158,735,702 RGD:1600115
RGD:1624291
G Nefl neurofilament light JBrowse link 15 44,799,378 44,803,251 RGD:1600115
RGD:1624291
G Nfia nuclear factor I/A JBrowse link 5 116,421,895 116,750,381 RGD:1624291
RGD:1600115
G Palm paralemmin JBrowse link 7 12,708,024 12,721,055 RGD:1624291
RGD:1600115
G Pfn1 profilin 1 JBrowse link 10 57,273,003 57,275,708 RGD:1600115
RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Sez6 seizure related 6 homolog JBrowse link 10 64,865,802 64,915,461 RGD:1624291
RGD:1600115
G Sez6l seizure related 6 homolog like JBrowse link 12 50,090,345 50,243,020 RGD:1624291
RGD:1600115
G Sez6l2 seizure related 6 homolog like 2 JBrowse link 1 198,383,201 198,403,544 RGD:1624291
RGD:1600115
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:8553517
G Sybu syntabulin JBrowse link 7 83,600,614 83,670,121 RGD:13217418
negative regulation of synapse maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef15 Rho guanine nucleotide exchange factor 15 JBrowse link 10 55,532,097 55,545,675 RGD:1624291
RGD:1600115
G Neurod2 neuronal differentiation 2 JBrowse link 10 86,280,865 86,282,681 RGD:1624291
RGD:1600115
G Nfatc4 nuclear factor of activated T-cells 4 JBrowse link 15 34,493,163 34,502,238 RGD:1624291
RGD:1600115
positive regulation of synapse maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adgrl1 adhesion G protein-coupled receptor L1 JBrowse link 19 25,029,037 25,069,146 RGD:8553824
G Anapc2 anaphase promoting complex subunit 2 JBrowse link 3 2,490,496 2,502,247 RGD:1624291
RGD:1600115
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:8553829
G Cdc20 cell division cycle 20 JBrowse link 5 137,260,728 137,264,931 RGD:1624291
RGD:1600115
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1600115
RGD:1624291
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:10002783
G Neurl1 neuralized E3 ubiquitin protein ligase 1 JBrowse link 1 266,953,006 267,038,879 RGD:1624291
RGD:1600115
G Neurod2 neuronal differentiation 2 JBrowse link 10 86,280,865 86,282,681 RGD:1624291
RGD:1600115
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1624291
RGD:1600115
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1624291
RGD:1600115
protein-containing complex assembly involved in synapse maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1624291
RGD:1600115
regulation of synapse maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clstn1 calsyntenin 1 JBrowse link 5 166,533,262 166,601,686 RGD:1600115
RGD:1624291
G Disc1 DISC1 scaffold protein JBrowse link 19 57,818,838 58,069,992 RGD:1624291
RGD:1600115
G Nrg2 neuregulin 2 JBrowse link 18 28,835,391 29,015,552 RGD:11070025
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta JBrowse link 7 75,573,553 75,598,295 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17895
    developmental process 6321
      developmental maturation 321
        synapse maturation 31
          cell-cell adhesion involved in synapse maturation 0
          negative regulation of synapse maturation 3
          positive regulation of synapse maturation + 10
          protein-containing complex assembly involved in synapse maturation 1
          regulation of synapse maturation + 16
Path 2
Term Annotations click to browse term
  biological_process 17895
    developmental process 6321
      anatomical structure development 5927
        multicellular organism development 5423
          system development 5002
            nervous system development 2549
              synapse maturation 31
                cell-cell adhesion involved in synapse maturation 0
                negative regulation of synapse maturation 3
                positive regulation of synapse maturation + 10
                protein-containing complex assembly involved in synapse maturation 1
                regulation of synapse maturation + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.