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ONTOLOGY REPORT - ANNOTATIONS


Term:excitatory postsynaptic potential
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Accession:GO:0060079 term browser browse the term
Definition:A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
Synonyms:exact_synonym: regulation of excitatory post-synaptic membrane potential
 related_synonym: regulation of EPSP


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excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:2317911
RGD:1624291
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1625443
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:5129150
G Atxn1 ataxin 1 JBrowse link 17 19,160,986 19,533,814 RGD:1624291
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:1600576
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:1624291
RGD:1600115
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit JBrowse link 3 60,445,657 60,460,724 RGD:1600115
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit JBrowse link 1 167,206,722 167,212,199 RGD:1600115
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit JBrowse link 15 42,808,897 42,825,179 RGD:1600115
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit JBrowse link 8 59,594,007 59,607,122 RGD:1624291
RGD:1600115
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:1600115
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit JBrowse link 8 59,561,817 59,590,172 RGD:1600115
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit JBrowse link 16 68,860,018 68,866,718 RGD:1600115
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1600115
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit JBrowse link 14 43,883,450 43,890,171 RGD:1600115
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit JBrowse link 10 56,390,671 56,403,255 RGD:1600115
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:1600115
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit JBrowse link 16 68,876,442 68,913,628 RGD:1600115
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit JBrowse link 8 59,610,489 59,629,073 RGD:1600115
G Chrnd cholinergic receptor nicotinic delta subunit JBrowse link 9 94,286,550 94,294,968 RGD:1600115
G Chrne cholinergic receptor nicotinic epsilon subunit JBrowse link 10 57,238,960 57,246,750 RGD:1600115
G Chrng cholinergic receptor nicotinic gamma subunit JBrowse link 9 94,302,218 94,308,591 RGD:1600115
G Dgki diacylglycerol kinase, iota JBrowse link 4 64,365,115 64,831,473 RGD:1624291
RGD:1600115
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624291
RGD:1600115
G Glra1 glycine receptor, alpha 1 JBrowse link 10 40,851,955 40,954,364 RGD:1600115
G Glra2 glycine receptor, alpha 2 JBrowse link X 30,612,894 30,832,078 RGD:1600115
G Glra3 glycine receptor, alpha 3 JBrowse link 16 37,676,959 37,908,221 RGD:1600115
G Glra4 glycine receptor, alpha 4 JBrowse link X 107,416,019 107,447,253 RGD:1600115
G Glrb glycine receptor, beta JBrowse link 2 179,768,040 179,842,612 RGD:1600115
G Grid2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 4 94,068,112 95,476,864 RGD:1624291
RGD:1600115
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1600115
RGD:1624291
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:1624291
RGD:1600115
G Grik5 glutamate ionotropic receptor kainate type subunit 5 JBrowse link 1 81,885,516 81,946,731 RGD:1624291
RGD:1600115
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:1600115
RGD:1624291
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:2325882
RGD:13792537
RGD:1624291
RGD:1600115
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:1624291
RGD:13792537
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C JBrowse link 10 103,798,290 103,816,923 RGD:1600115
RGD:13792537
RGD:1624291
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D JBrowse link 1 101,819,068 101,859,146 RGD:1624291
RGD:13792537
G Hcrt hypocretin neuropeptide precursor JBrowse link 10 88,669,216 88,670,430 RGD:1600968
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 JBrowse link 7 130,430,588 130,440,838 RGD:1624291
RGD:1600115
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1624291
RGD:1600115
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:1624291
G Mpp2 membrane palmitoylated protein 2 JBrowse link 10 89,998,284 90,030,766 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Npas4 neuronal PAS domain protein 4 JBrowse link 1 220,260,310 220,278,177 RGD:1624291
RGD:1600115
G Npff neuropeptide FF-amide peptide precursor JBrowse link 7 144,127,084 144,127,873 RGD:2316571
RGD:13792537
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:2316604
G P2rx1 purinergic receptor P2X 1 JBrowse link 10 59,566,268 59,581,328 RGD:1600115
G P2rx2 purinergic receptor P2X 2 JBrowse link 12 52,397,666 52,401,005 RGD:1600115
G P2rx3 purinergic receptor P2X 3 JBrowse link 3 72,403,992 72,447,801 RGD:1600115
G P2rx4 purinergic receptor P2X 4 JBrowse link 12 39,308,022 39,325,673 RGD:1624291
RGD:1600115
G P2rx5 purinergic receptor P2X 5 JBrowse link 10 59,725,438 59,737,126 RGD:1600115
G P2rx6 purinergic receptor P2X 6 JBrowse link 11 87,434,929 87,445,221 RGD:1600115
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1600115
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A JBrowse link 4 29,976,485 30,247,371 RGD:10043779
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:1624291
RGD:1600115
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 JBrowse link 13 44,578,208 44,649,876 RGD:1624291
RGD:1600115
G Sez6 seizure related 6 homolog JBrowse link 10 64,865,802 64,915,461 RGD:1624291
RGD:1600115
G Slc17a7 solute carrier family 17 member 7 JBrowse link 1 101,161,265 101,172,292 RGD:1624291
RGD:1600115
G Slc29a1 solute carrier family 29 member 1 JBrowse link 9 17,784,468 17,799,008 RGD:1299118
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
RGD:1600115
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:1600115
evoked excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Begain brain-enriched guanylate kinase-associated JBrowse link 6 132,936,964 132,972,569 RGD:1624291
modulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
RGD:1600115
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1624291
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 JBrowse link 9 11,031,847 11,055,285 RGD:13463484
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:11535099
G Tmem108 transmembrane protein 108 JBrowse link 8 111,968,568 112,265,623 RGD:1624291
RGD:1600115
G Zmynd8 zinc finger, MYND-type containing 8 JBrowse link 3 162,480,766 162,594,145 RGD:8554267
negative regulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbln1 cerebellin 1 precursor JBrowse link 19 20,607,507 20,611,316 RGD:1624291
RGD:1600115
G Celf4 CUGBP, Elav-like family member 4 JBrowse link 18 17,689,090 18,079,835 RGD:1624291
G Eif4a3 eukaryotic translation initiation factor 4A3 JBrowse link 10 108,415,201 108,425,195 RGD:10044262
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Mtmr2 myotubularin related protein 2 JBrowse link 8 12,283,471 12,334,014 RGD:8553482
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:1642608
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10413844
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G S1pr2 sphingosine-1-phosphate receptor 2 JBrowse link 8 21,984,914 21,995,806 RGD:1624291
RGD:1600115
negative regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:13209020
positive regulation of excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Baiap2 BAR/IMD domain containing adaptor protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:9684984
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:13514092
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1600115
RGD:1624291
G Cux2 cut-like homeobox 2 JBrowse link 12 40,016,774 40,221,067 RGD:1624291
RGD:1600115
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10398809
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:8554754
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:7248611
G Dvl1 dishevelled segment polarity protein 1 JBrowse link 5 173,295,948 173,308,014 RGD:10449514
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:8554754
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:8554754
G Grip2 glutamate receptor interacting protein 2 JBrowse link 4 123,585,184 123,636,040 RGD:4107359
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13506836
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:4107027
G LOC103690160 SH3 and multiple ankyrin repeat domains protein 2-like JBrowse link 1 215,208,591 215,246,638 RGD:13792537
G Neto1 neuropilin and tolloid like 1 JBrowse link 18 83,471,342 83,585,043 RGD:1624291
RGD:1600115
G Neto2 neuropilin and tolloid like 2 JBrowse link 19 22,450,579 22,486,530 RGD:1624291
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:10414080
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:8553502
RGD:1624291
RGD:8554379
RGD:8554760
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1600115
RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:8554098
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:8553497
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1600115
RGD:1624291
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:13524537
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:1624291
RGD:1600115
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1624291
RGD:1600115
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:1624291
RGD:13792537
RGD:1600115
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:13792537
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1600115
RGD:13792537
RGD:1624291
RGD:7349315
G Ssh1 slingshot protein phosphatase 1 JBrowse link 12 48,403,184 48,447,964 RGD:11535133
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:1624291
RGD:1600115
G Stx1b syntaxin 1B JBrowse link 1 199,251,842 199,270,465 RGD:1624291
RGD:1600115
G Tbc1d24 TBC1 domain family, member 24 JBrowse link 10 13,551,100 13,576,739 RGD:11537391
G Wnt7a Wnt family member 7A JBrowse link 4 122,994,425 123,040,609 RGD:1624291
RGD:1600115
positive regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1600115
RGD:1624291
G Afdn afadin, adherens junction formation factor JBrowse link 1 53,713,873 53,861,918 RGD:13838731
G Igsf11 immunoglobulin superfamily, member 11 JBrowse link 11 64,286,691 64,421,248 RGD:11085699
regulation of acetylcholine-gated cation channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:704387
regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 1 225,035,956 225,046,137 RGD:1624291
G Dmpk DM1 protein kinase JBrowse link 1 79,988,096 79,999,358 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological quality 4168
        regulation of membrane potential 467
          regulation of postsynaptic membrane potential 158
            excitatory postsynaptic potential 113
              evoked excitatory postsynaptic potential 1
              mini excitatory postsynaptic potential + 4
              modulation of excitatory postsynaptic potential + 55
              negative regulation of excitatory postsynaptic potential + 11
              positive regulation of excitatory postsynaptic potential + 40
Path 2
Term Annotations click to browse term
  biological_process 18166
    cellular process 16266
      cell communication 7200
        cell-cell signaling 1630
          synaptic signaling 888
            trans-synaptic signaling 864
              anterograde trans-synaptic signaling 855
                chemical synaptic transmission 855
                  chemical synaptic transmission, postsynaptic 122
                    excitatory postsynaptic potential 113
                      evoked excitatory postsynaptic potential 1
                      mini excitatory postsynaptic potential + 4
                      modulation of excitatory postsynaptic potential + 55
                      negative regulation of excitatory postsynaptic potential + 11
                      positive regulation of excitatory postsynaptic potential + 40
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.