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ONTOLOGY REPORT - ANNOTATIONS


Term:inhibitory postsynaptic potential
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Accession:GO:0060080 term browser browse the term
Definition:A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
Synonyms:exact_synonym: regulation of inhibitory post-synaptic membrane potential
 related_synonym: IPSP


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inhibitory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO MGI:MGI:95815 (MGI:MGI:1354133|PMID:10704492) RGD PMID:10704492 MGI:MGI:1354133 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18262504 RGD:5129137 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO MGI:MGI:2176750 (MGI:MGI:5559620|PMID:24201284) RGD PMID:24201284 MGI:MGI:5559620 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit ISO
IEA
MGI:MGI:3700204|MGI:MGI:3700205 (MGI:MGI:3699045|PMID:17146052)
GO_REF:0000107
RGD
Ensembl
PMID:17146052 GO_REF:0000107, MGI:MGI:3699045 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IMP RGD PMID:19748551 RGD:4891944 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Drd4 dopamine receptor D4 IEA
ISO
GO_REF:0000107
MGI:MGI:2178631|MGI:MGI:3576789 (MGI:MGI:1934688|PMID:11356863), (MGI:MGI:3575384|PMID:14684868)
Ensembl
RGD
PMID:11356863, PMID:14684868 GO_REF:0000107, MGI:MGI:1934688, MGI:MGI:3575384 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 ISO
IEA
(MGI:MGI:5619469|PMID:19846622)
GO_REF:0000107
RGD
Ensembl
PMID:19846622 GO_REF:0000107, MGI:MGI:5619469 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Glra1 glycine receptor, alpha 1 ISS
ISO
GO_REF:0000024
MGI:MGI:3696673 (MGI:MGI:3695847|PMID:17114051), (MGI:MGI:5707576|PMID:24801766)
UniProt
RGD
PMID:17114051, PMID:24801766 GO_REF:0000024, MGI:MGI:3695847, MGI:MGI:5707576 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 ISO MGI:MGI:2176347|MGI:MGI:95815 (MGI:MGI:1927732|PMID:11144357), (MGI:MGI:2387276|PMID:12223554) RGD PMID:11144357, PMID:12223554 MGI:MGI:1927732, MGI:MGI:2387276 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO MGI:MGI:1857979|MGI:MGI:95814|MGI:MGI:99402 (MGI:MGI:1327732|PMID:9880586), (MGI:MGI:1354133|PMID:10704492), (MGI:MGI:1927732|PMID:11144357), (MGI:MGI:2387276|PMID:12223554) RGD PMID:9880586, PMID:10704492, PMID:11144357, PMID:12223554 MGI:MGI:1327732, MGI:MGI:1354133, MGI:MGI:1927732, MGI:MGI:2387276 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Insyn1 inhibitory synaptic factor 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:5800345|PMID:27609886)
UniProt
RGD
PMID:27609886 GO_REF:0000024, MGI:MGI:5800345 NCBI chr 8:63,286,841...63,297,080
Ensembl chr 8:63,286,773...63,301,914
JBrowse link
G Insyn2a inhibitory synaptic factor 2A ISO
IBA
(MGI:MGI:5800345|PMID:27609886)
PMID:21873635
RGD PMID:27609886, PMID:21873635 MGI:MGI:5800345, RGD:13792537 NCBI chr 1:207,116,698...207,171,885
Ensembl chr 1:207,116,717...207,171,760
JBrowse link
G Nlgn1 neuroligin 1 NOT ISO
IDA
(MGI:MGI:3803801|PMID:17582332) RGD PMID:17582332, PMID:17582332 MGI:MGI:3803801, RGD:8553502 NCBI chr 2:111,057,291...111,973,681
Ensembl chr 2:111,057,291...111,793,326
JBrowse link
G Nlgn3 neuroligin 3 IDA
ISO
IEA
PMID:19406211
MGI:MGI:3758949 (MGI:MGI:3758357|PMID:17823315), (MGI:MGI:5286761|PMID:21808020)
GO_REF:0000107
RGD
Ensembl
PMID:17823315, PMID:21808020, PMID:19406211 GO_REF:0000107, MGI:MGI:3758357, MGI:MGI:5286761, RGD:8554851 NCBI chr  X:71,199,390...71,227,460
Ensembl chr  X:71,199,491...71,222,732
JBrowse link
G Npas4 neuronal PAS domain protein 4 ISS
ISO
GO_REF:0000024
MGI:MGI:3828100 (MGI:MGI:3826741|PMID:18815592), (MGI:MGI:5559620|PMID:24201284), (MGI:MGI:5602898|PMID:24855953)
UniProt
RGD
PMID:18815592, PMID:24201284, PMID:24855953 GO_REF:0000024, MGI:MGI:3826741, MGI:MGI:5559620, MGI:MGI:5602898 NCBI chr 1:220,260,310...220,278,177
Ensembl chr 1:220,261,008...220,265,772
JBrowse link
modulation of inhibitory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 IMP RGD PMID:19174472 RGD:10398809 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
positive regulation of inhibitory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11495935 RGD:10047060 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Igsf9b immunoglobulin superfamily, member 9B ISO (MGI:MGI:5514300|PMID:23751499) RGD PMID:23751499 MGI:MGI:5514300 NCBI chr 8:28,352,497...28,398,659
Ensembl chr 8:28,352,772...28,387,383
JBrowse link
G Nlgn2 neuroligin 2 IMP
ISO
IEA
PMID:18550748
(MGI:MGI:3803801|PMID:17582332), (MGI:MGI:5284797|PMID:15620359)
GO_REF:0000107
RGD
Ensembl
PMID:15620359, PMID:17582332, PMID:18550748 GO_REF:0000107, MGI:MGI:3803801, MGI:MGI:5284797, RGD:8554527 NCBI chr10:56,431,586...56,444,847
Ensembl chr10:56,431,573...56,444,847
JBrowse link
G Nlgn3 neuroligin 3 IDA RGD PMID:19406211 RGD:8554851 NCBI chr  X:71,199,390...71,227,460
Ensembl chr  X:71,199,491...71,222,732
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:15664687 RGD:9831120 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 ISO
ISS
IGI
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (MGI:MGI:4887275|PMID:21262469)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:21262469, PMID:21262469 GO_REF:0000024, MGI:MGI:4887275, RGD:10047275 NCBI chr 9:28,440,408...28,973,246
Ensembl chr 9:28,442,229...28,973,246
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 ISO
ISS
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (MGI:MGI:4887275|PMID:21262469)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:21262469 GO_REF:0000024, MGI:MGI:4887275 NCBI chr 7:78,091,998...78,594,164
Ensembl chr 7:78,092,037...78,594,138
JBrowse link
G Unc13b unc-13 homolog B IGI PMID:21262469 ParkinsonsUK-UCL PMID:21262469, PMID:21262469 RGD:10047275, RGD:10047275 NCBI chr 5:58,505,449...58,714,396
Ensembl chr 5:58,505,500...58,715,576
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    biological regulation 13760
      regulation of biological quality 4283
        regulation of membrane potential 483
          regulation of postsynaptic membrane potential 162
            inhibitory postsynaptic potential 23
              modulation of inhibitory postsynaptic potential + 9
              positive regulation of inhibitory postsynaptic potential 8
Path 2
Term Annotations click to browse term
  biological_process 20015
    cellular process 18788
      cell communication 7670
        cell-cell signaling 1754
          synaptic signaling 897
            trans-synaptic signaling 871
              anterograde trans-synaptic signaling 864
                chemical synaptic transmission 864
                  chemical synaptic transmission, postsynaptic 127
                    inhibitory postsynaptic potential 23
                      modulation of inhibitory postsynaptic potential + 9
                      positive regulation of inhibitory postsynaptic potential 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.