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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of syncytium formation by plasma membrane fusion
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Accession:GO:0060143 term browser browse the term
Definition:Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


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positive regulation of syncytium formation by plasma membrane fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk1 calcium/calmodulin-dependent protein kinase I ISO (PMID:23867755) RGD PMID:23867755 NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177
JBrowse link
G Gcm1 glial cells missing transcription factor 1 ISO MGI:MGI:97308 (MGI:MGI:5049808|PMID:21558372) RGD PMID:21558372 MGI:MGI:5049808 NCBI chr 8:85,355,766...85,369,002
Ensembl chr 8:85,355,766...85,369,002
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 ISO
IEA
(PMID:23867755)
GO_REF:0000107
RGD
Ensembl
PMID:23867755 GO_REF:0000107 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551
JBrowse link
positive regulation of macrophage fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 ISO (PMID:11831872) RGD PMID:11831872 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein ISO MGI:MGI:1921864 (MGI:MGI:3588832|PMID:16061724), (MGI:MGI:5426135|PMID:16937266), (MGI:MGI:5462143|PMID:22865856) RGD PMID:16061724, PMID:16937266, PMID:22865856 MGI:MGI:3588832, MGI:MGI:5426135, MGI:MGI:5462143 NCBI chr 7:78,642,016...78,651,763
Ensembl chr 7:78,649,875...78,650,906
JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein ISO MGI:MGI:1923016 (MGI:MGI:5462143|PMID:22865856) RGD PMID:22865856 MGI:MGI:5462143 NCBI chr 3:162,073,573...162,080,487
Ensembl chr 3:162,075,340...162,080,192
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 ISO (MGI:MGI:6142486|PMID:18957693) RGD PMID:18957693 MGI:MGI:6142486 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp ISO
IBA
(PMID:18957693)
PMID:21873635
(MGI:MGI:6142486|PMID:18957693)
RGD PMID:18957693, PMID:21873635 MGI:MGI:6142486, RGD:13792537 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link
positive regulation of myoblast fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 ISO (MGI:MGI:5498642|PMID:23615608) RGD PMID:23615608 MGI:MGI:5498642 NCBI chr 7:115,766,484...115,828,514 JBrowse link
G Capn2 calpain 2 IMP RGD PMID:7657725 RGD:13792659 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Cd53 Cd53 molecule ISO
ISS
(MGI:MGI:5526919|PMID:22847234)
GO_REF:0000024
RGD
UniProt
PMID:22847234 GO_REF:0000024, MGI:MGI:5526919 NCBI chr 2:209,489,279...209,537,098
Ensembl chr 2:209,489,279...209,537,087
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO (MGI:MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:MGI:5532227 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO (MGI:MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:MGI:5532227 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Ehd1 EH-domain containing 1 ISO
ISS
(MGI:MGI:5487527|PMID:21177873)
GO_REF:0000024
RGD
UniProt
PMID:21177873 GO_REF:0000024, MGI:MGI:5487527 NCBI chr 1:221,644,867...221,667,242
Ensembl chr 1:221,644,867...221,667,239
JBrowse link
G Ehd2 EH-domain containing 2 ISO
ISS
(MGI:MGI:5487527|PMID:21177873)
GO_REF:0000024
RGD
UniProt
PMID:21177873 GO_REF:0000024, MGI:MGI:5487527 NCBI chr 1:77,847,599...77,865,870
Ensembl chr 1:77,847,600...77,865,870
JBrowse link
G Flot1 flotillin 1 ISO (PMID:24046456)
(MGI:MGI:5634880|PMID:24046456)
RGD PMID:24046456 MGI:MGI:5634880 NCBI chr20:3,427,890...3,438,418
Ensembl chr20:3,427,880...3,438,396
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand ISO (MGI:MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:MGI:5532227 NCBI chr 1:101,126,006...101,131,413
Ensembl chr 1:101,124,479...101,131,413
JBrowse link
G Gdf15 growth differentiation factor 15 ISO
IEA
(MGI:MGI:5532227|PMID:23844157)
GO_REF:0000107
RGD
Ensembl
PMID:23844157 GO_REF:0000107, MGI:MGI:5532227 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Il4 interleukin 4 ISO
IBA
MGI:MGI:1857194 (MGI:MGI:3621675|PMID:12757709)
PMID:21873635
RGD PMID:12757709, PMID:21873635 MGI:MGI:3621675, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor ISO MGI:MGI:1861951 (MGI:MGI:3621675|PMID:12757709) RGD PMID:12757709 MGI:MGI:3621675 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Mapk14 mitogen activated protein kinase 14 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5526919|PMID:22847234)
Ensembl
UniProt
RGD
PMID:22847234 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5526919 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Myf5 myogenic factor 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:49,729,533...49,732,974
Ensembl chr 7:49,729,533...49,732,764
JBrowse link
G Myf6 myogenic factor 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:49,739,643...49,741,490
Ensembl chr 7:49,739,646...49,741,540
JBrowse link
G Myod1 myogenic differentiation 1 ISO
IBA
IEA
(PMID:10672515)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:10672515, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Myog myogenin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 ISO MGI:MGI:2182740 (MGI:MGI:3621675|PMID:12757709) RGD PMID:12757709 MGI:MGI:3621675 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 ISO
ISS
(PMID:17150207)
GO_REF:0000024
RGD
UniProt
PMID:17150207 GO_REF:0000024 NCBI chr17:42,324,594...42,549,907
Ensembl chr17:42,324,594...42,422,053
JBrowse link
G Scgb3a1 secretoglobin, family 3A, member 1 ISO
IBA
(MGI:MGI:5532227|PMID:23844157)
PMID:21873635
RGD PMID:23844157, PMID:21873635 MGI:MGI:5532227, RGD:13792537 NCBI chr10:35,133,561...35,134,868
Ensembl chr10:35,133,252...35,135,466
JBrowse link
G Tnfsf14 TNF superfamily member 14 ISO (MGI:MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:MGI:5532227 NCBI chr 9:9,761,363...9,765,461
Ensembl chr 9:9,761,536...9,765,186
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      positive regulation of developmental process 1629
        positive regulation of syncytium formation by plasma membrane fusion 29
          positive regulation of macrophage fusion 5
          positive regulation of myoblast fusion 21
          positive regulation of syncytium formation by virus 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        anatomical structure morphogenesis 2872
          anatomical structure formation involved in morphogenesis 1210
            syncytium formation 66
              syncytium formation by plasma membrane fusion 64
                regulation of syncytium formation by plasma membrane fusion 34
                  positive regulation of syncytium formation by plasma membrane fusion 29
                    positive regulation of macrophage fusion 5
                    positive regulation of myoblast fusion 21
                    positive regulation of syncytium formation by virus 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.