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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of posttranscriptional gene silencing
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Accession:GO:0060147 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.


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negative regulation of gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnd1 DND microRNA-mediated repression inhibitor 1 ISO
IBA
(PMID:18155131)
PMID:21873635
RGD PMID:18155131, PMID:21873635 RGD:13792537 NCBI chr18:29,608,588...29,611,212
Ensembl chr18:29,608,588...29,611,212
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 ISS
ISO
GO_REF:0000024
RNAcentral:URS000024463E_9606 (PMID:26595526), (PMID:27089893)
UniProt
RGD
PMID:26595526, PMID:27089893 GO_REF:0000024 NCBI chr12:2,461,502...2,502,432
Ensembl chr12:2,461,502...2,502,432
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:19409607) RGD PMID:19409607 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO (PMID:28522568) RGD PMID:28522568 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase ISO
IBA
ISS
(PMID:23063121)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23063121, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:141,132,106...141,136,700
Ensembl chr 7:141,132,133...141,136,700
JBrowse link
G Lin28b lin-28 homolog B ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:50,482,536...50,580,273
Ensembl chr20:50,486,809...50,564,987
JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 ISO UniProtKB:P40763 (PMID:31507089) RGD PMID:31507089 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lin28b lin-28 homolog B ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:50,482,536...50,580,273
Ensembl chr20:50,486,809...50,564,987
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO (PMID:31507089) RGD PMID:31507089 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 ISO (PMID:20388878) RGD PMID:20388878 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO (MGI:MGI:5562625|PMID:24161931) RGD PMID:24161931 MGI:MGI:5562625 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:31124343), (PMID:31824476) RGD PMID:31124343, PMID:31824476 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 ISO MGI:MGI:1890508 (MGI:MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:MGI:5013521 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Zc3h10 zinc finger CCCH type containing 10 ISO (PMID:28431233) RGD PMID:28431233 NCBI chr 7:2,968,428...2,972,521
Ensembl chr 7:2,968,435...2,972,521
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A ISO
ISS
(PMID:22055188)
GO_REF:0000024
RGD
UniProt
PMID:22055188 GO_REF:0000024 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 ISO MGI:MGI:2180033|MGI:MGI:98834 (MGI:MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:MGI:5013521 NCBI chr 5:139,982,404...140,015,541
Ensembl chr 5:139,983,680...140,015,541
JBrowse link
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tert telomerase reverse transcriptase ISO (PMID:19701182) RGD PMID:19701182 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
negative regulation of RNA interference term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific ISO
IEA
(MGI:MGI:3573853|PMID:15556947)
GO_REF:0000107
RGD
Ensembl
PMID:15556947 GO_REF:0000107, MGI:MGI:3573853 NCBI chr 2:189,045,551...189,085,448
Ensembl chr 2:189,062,443...189,083,236
JBrowse link
positive regulation of gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002945.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:89,967,031...90,000,386 JBrowse link
G Ajuba ajuba LIM protein ISO
IBA
ISS
(PMID:20616046)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20616046, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr15:33,208,210...33,218,456
Ensembl chr15:33,208,216...33,218,456
JBrowse link
G Dhx9 DExH-box helicase 9 ISO (PMID:17531811) RGD PMID:17531811 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Fmr1 FMRP translational regulator 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4868681|PMID:20159450)
(PMID:17057366)
Ensembl
UniProt
RGD
PMID:17057366, PMID:20159450 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4868681 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fxr1 FMR1 autosomal homolog 1 ISO
IEA
ISS
(PMID:17057366)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17057366 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:120,529,716...120,570,356
Ensembl chr 2:120,512,899...120,570,355
JBrowse link
G Limd1 LIM domains containing 1 ISO
IBA
ISS
(PMID:20616046)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20616046, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:132,553,218...132,598,826
Ensembl chr 8:132,553,218...132,598,812
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IMP PMID:24676391 BHF-UCL PMID:24676391 RGD:10400879 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Pum1 pumilio RNA-binding family member 1 ISO (PMID:20818387), (PMID:22345517) RGD PMID:20818387, PMID:22345517 NCBI chr 5:148,781,239...148,911,776
Ensembl chr 5:148,781,222...148,911,803
JBrowse link
G Pum2 pumilio RNA-binding family member 2 ISO (PMID:22345517) RGD PMID:22345517 NCBI chr 6:33,786,184...33,865,693
Ensembl chr 6:33,786,197...33,865,687
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO (PMID:23820254) RGD PMID:23820254 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Trim71 tripartite motif containing 71 ISO (MGI:MGI:4438512|PMID:19898466) RGD PMID:19898466 MGI:MGI:4438512 NCBI chr 8:122,553,015...122,604,787
Ensembl chr 8:122,553,015...122,604,787
JBrowse link
G Wtip WT1 interacting protein ISO (PMID:20616046) RGD PMID:20616046 NCBI chr 1:89,966,496...89,999,892 JBrowse link
G Zfp36 zinc finger protein 36 ISO
ISS
(PMID:15766526)
GO_REF:0000024
RGD
UniProt
PMID:15766526 GO_REF:0000024 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
positive regulation of miRNA mediated inhibition of translation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 IEA
ISO
GO_REF:0000107
(PMID:23409027)
Ensembl
RGD
PMID:23409027 GO_REF:0000107 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Ddx6 DEAD-box helicase 6 ISO (PMID:27342281) RGD PMID:27342281 NCBI chr 8:48,924,768...48,961,394
Ensembl chr 8:48,925,604...48,958,026
JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 ISO (PMID:28487484) RGD PMID:28487484 NCBI chr 9:94,310,476...94,325,445
Ensembl chr 9:94,307,852...94,336,831
JBrowse link
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 ISO (PMID:24335285), (PMID:27342281), (PMID:28487484), (PMID:32354837) RGD PMID:24335285, PMID:27342281, PMID:28487484, PMID:32354837 NCBI chr14:83,412,843...83,455,694
Ensembl chr14:83,412,968...83,455,456
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 ISO (PMID:23409027) RGD PMID:23409027 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO
IEA
(PMID:23820254)
GO_REF:0000107
RGD
Ensembl
PMID:23820254 GO_REF:0000107 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B ISO (PMID:32354837) RGD PMID:32354837 NCBI chr 7:121,930,610...122,147,934
Ensembl chr 7:121,930,615...122,147,934
JBrowse link
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
(PMID:18548003)
Ensembl
RGD
PMID:18548003 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Ddx5 DEAD-box helicase 5 ISO (PMID:18548003) RGD PMID:18548003 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Egfr epidermal growth factor receptor ISO (PMID:21673316) RGD PMID:21673316 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Il6 interleukin 6 ISO (PMID:27252421) RGD PMID:27252421 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lin28a lin-28 homolog A ISO (MGI:MGI:5294254|PMID:21962509) RGD PMID:21962509 MGI:MGI:5294254 NCBI chr 5:152,230,343...152,247,873
Ensembl chr 5:152,230,343...152,247,332
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO
IEA
(PMID:24375836)
GO_REF:0000107
RGD
Ensembl
PMID:24375836 GO_REF:0000107 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO (PMID:24375836) RGD PMID:24375836 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Myocd myocardin ISO
IEA
(MGI:MGI:6414695|PMID:28342807)
GO_REF:0000107
RGD
Ensembl
PMID:28342807 GO_REF:0000107, MGI:MGI:6414695 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 ISO MGI:MGI:2385930 (MGI:MGI:5574156|PMID:24349493) RGD PMID:24349493 MGI:MGI:5574156 NCBI chr 2:5,569,954...5,579,894
Ensembl chr 2:5,569,935...5,579,894
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO (PMID:26020802) RGD PMID:26020802 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (PMID:18548003) RGD PMID:18548003 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tp53 tumor protein p53 ISO (PMID:22578566), (PMID:26100857) RGD PMID:22578566, PMID:26100857 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
positive regulation of RNA interference term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xpo5 exportin 5 ISO (PMID:15613540) RGD PMID:15613540 NCBI chr 9:17,125,201...17,163,170
Ensembl chr 9:17,125,201...17,163,170
JBrowse link
regulation of gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmr1 FMRP translational regulator 1 ISO
ISS
(PMID:25464849)
GO_REF:0000024
RGD
UniProt
PMID:25464849 GO_REF:0000024 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Lin28a lin-28 homolog A ISO MGI:MGI:2685973 (MGI:MGI:4438512|PMID:19898466) RGD PMID:19898466 MGI:MGI:4438512 NCBI chr 5:152,230,343...152,247,873
Ensembl chr 5:152,230,343...152,247,332
JBrowse link
G Mael maelstrom spermatogenic transposon silencer IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:84,412,569...84,452,140
Ensembl chr13:84,383,670...84,452,181
JBrowse link
G Mir154 microRNA 154 ISO (MGI:MGI:5705446|PMID:25959411) RGD PMID:25959411 MGI:MGI:5705446 NCBI chr 6:133,888,586...133,888,669
Ensembl chr 6:133,888,586...133,888,669
JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C ISO MGI:MGI:4124681 (MGI:MGI:5315650|PMID:22187428) RGD PMID:22187428 MGI:MGI:5315650 NCBI chr10:106,698,359...106,763,639
Ensembl chr10:106,712,127...106,762,043
JBrowse link
G Trim71 tripartite motif containing 71 ISS
ISO
GO_REF:0000024
MGI:MGI:1890546 (MGI:MGI:4438512|PMID:19898466), (MGI:MGI:5448492|PMID:22735451)
UniProt
RGD
PMID:19898466, PMID:22735451 GO_REF:0000024, MGI:MGI:4438512, MGI:MGI:5448492 NCBI chr 8:122,553,015...122,604,787
Ensembl chr 8:122,553,015...122,604,787
JBrowse link
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tarbp2 TARBP2 subunit of RISC loading complex ISO MGI:MGI:2135565|MGI:MGI:5645258 (MGI:MGI:6094668|PMID:27159388) RGD PMID:27159388 MGI:MGI:6094668 NCBI chr 7:144,121,688...144,126,860
Ensembl chr 7:144,121,744...144,126,857
JBrowse link
regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tarbp2 TARBP2 subunit of RISC loading complex IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:144,121,688...144,126,860
Ensembl chr 7:144,121,744...144,126,857
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    regulation of biological process 13073
      regulation of cellular process 12563
        regulation of gene silencing 77
          regulation of posttranscriptional gene silencing 53
            negative regulation of posttranscriptional gene silencing + 21
            positive regulation of posttranscriptional gene silencing + 32
            regulation of RNA interference + 4
            regulation of gene silencing by miRNA + 50
Path 2
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      organic substance metabolic process 11639
        macromolecule metabolic process 10084
          regulation of macromolecule metabolic process 6495
            regulation of gene expression 4799
              negative regulation of gene expression 2157
                gene silencing 256
                  regulation of gene silencing 77
                    regulation of posttranscriptional gene silencing 53
                      negative regulation of posttranscriptional gene silencing + 21
                      positive regulation of posttranscriptional gene silencing + 32
                      regulation of RNA interference + 4
                      regulation of gene silencing by miRNA + 50
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.