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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of transcription initiation from RNA polymerase II promoter
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Accession:GO:0060261 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.


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positive regulation of transcription initiation from RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHX36 DEAH-box helicase 36 ISO (PMID:21993297) UniProt PMID:21993297 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO (MGI:MGI:5314556|PMID:22323595) MGI PMID:22323595 MGI:MGI:5314556 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor ISO (MGI:MGI:5314556|PMID:22323595) MGI PMID:22323595 MGI:MGI:5314556 NCBI chr10:44,703,720...44,784,948 JBrowse link
G HNF1A HNF1 homeobox A ISO (PMID:15355349) UniProtKB PMID:15355349 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911
JBrowse link
G HNF1B HNF1 homeobox B ISO (PMID:15355349) UniProtKB PMID:15355349 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863
JBrowse link
G IRF8 interferon regulatory factor 8 NOT ISO (MGI:MGI:5448615|PMID:22942423) MGI PMID:22942423 MGI:MGI:5448615 NCBI chr16:66,568,370...66,591,949
Ensembl chr16:85,905,334...85,929,073
JBrowse link
G MED1 mediator complex subunit 1 ISO (PMID:12218053), (PMID:16314496) UniProt PMID:12218053, PMID:16314496 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G MED12 mediator complex subunit 12 ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr  X:60,386,820...60,410,730
Ensembl chr  X:70,443,667...70,466,942
JBrowse link
G MED13 mediator complex subunit 13 ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr17:56,044,769...56,165,922
Ensembl chr17:61,157,691...61,274,505
JBrowse link
G MED14 mediator complex subunit 14 ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr  X:33,097,206...33,183,322
Ensembl chr  X:40,798,363...40,886,270
JBrowse link
G MED16 mediator complex subunit 16 ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr19:238,822...260,277
Ensembl chr19:841,367...863,080
JBrowse link
G MED17 mediator complex subunit 17 ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr11:88,806,209...88,835,138 JBrowse link
G MED24 mediator complex subunit 24 ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr17:17,234,660...17,269,794
Ensembl chr17:17,456,137...17,489,992
JBrowse link
G MED30 mediator complex subunit 30 ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr 8:114,211,278...114,230,838
Ensembl chr 8:116,732,283...116,752,249
JBrowse link
G MED4 mediator complex subunit 4 ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr13:29,227,620...29,247,082
Ensembl chr13:47,929,918...47,948,836
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO (MGI:MGI:6377809|PMID:26691508) CACAO PMID:26691508 MGI:MGI:6377809 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NKX2-5 NK2 homeobox 5 ISO (MGI:MGI:83559|PMID:8887666) BHF-UCL PMID:8887666 MGI:MGI:83559 NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514
JBrowse link
G PAXIP1 PAX interacting protein 1 ISO (MGI:MGI:4354659|PMID:19583951), (MGI:MGI:4821506|PMID:20671152)
(PMID:17925232)
UniProtKB PMID:17925232, PMID:19583951, PMID:20671152 MGI:MGI:4354659, MGI:MGI:4821506 NCBI chr 7:146,546,658...146,605,912
Ensembl chr 7:158,276,798...158,330,911
JBrowse link
G POU5F1 POU class 5 homeobox 1 ISO (MGI:MGI:6377809|PMID:26691508) CACAO PMID:26691508 MGI:MGI:6377809 NCBI chr 6:30,910,421...30,916,465
Ensembl chr 6:31,775,343...31,781,426
JBrowse link
G SRF serum response factor ISO (PMID:8887666) BHF-UCL PMID:8887666 NCBI chr 6:42,763,099...42,773,332
Ensembl chr 6:44,057,192...44,066,768
JBrowse link
G TAF6 TATA-box binding protein associated factor 6 ISO (PMID:11583621), (PMID:18628956) UniProt PMID:11583621, PMID:18628956 NCBI chr 7:92,142,646...92,154,951
Ensembl chr 7:105,575,861...105,588,142
JBrowse link
G XPA XPA, DNA damage recognition and repair factor ISO (MGI:MGI:5314556|PMID:22323595) MGI PMID:22323595 MGI:MGI:5314556 NCBI chr 9:68,726,723...68,788,049
Ensembl chr 9:96,886,795...96,909,254
JBrowse link
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor ISO (MGI:MGI:62922|PMID:8215422) MGI PMID:8215422 MGI:MGI:62922 NCBI chr 7:17,949,254...17,998,737 JBrowse link
G CAND1 cullin associated and neddylation dissociated 1 ISO PMID:10567521 UniProt PMID:10567521 RGD:8553447 NCBI chr12:21,592,833...21,638,382
Ensembl chr12:22,099,962...22,145,013
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130
JBrowse link
G ESR1 estrogen receptor 1 ISO (PMID:9841876) CAFA PMID:9841876 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G IKZF1 IKAROS family zinc finger 1 ISO (MGI:MGI:5317044|PMID:21245044) MGI PMID:21245044 MGI:MGI:5317044 NCBI chr 7:50,946,817...51,047,168
Ensembl chr 7:51,191,685...51,291,245
JBrowse link
G TP53 tumor protein p53 ISO (PMID:24289924) BHF-UCL PMID:24289924 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G WNT10B Wnt family member 10B ISO (MGI:MGI:3820325|PMID:19056892) MGI PMID:19056892 MGI:MGI:3820325 NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12564
    metabolic process 7979
      positive regulation of metabolic process 3445
        positive regulation of macromolecule metabolic process 3195
          positive regulation of gene expression 2133
            positive regulation of transcription, DNA-templated 1422
              positive regulation of transcription by RNA polymerase II 1139
                positive regulation of transcription initiation from RNA polymerase II promoter 29
                  positive regulation of RNA polymerase II transcription preinitiation complex assembly 7
Path 2
Term Annotations click to browse term
  biological_process 12564
    metabolic process 7979
      cellular metabolic process 7331
        cellular aromatic compound metabolic process 3878
          nucleobase-containing compound metabolic process 3701
            nucleic acid metabolic process 3398
              RNA metabolic process 3010
                RNA biosynthetic process 2446
                  regulation of RNA biosynthetic process 2368
                    regulation of nucleic acid-templated transcription 2363
                      regulation of transcription, DNA-templated 2355
                        regulation of DNA-templated transcription, initiation 45
                          positive regulation of DNA-templated transcription, initiation 37
                            positive regulation of transcription initiation from RNA polymerase II promoter 29
                              positive regulation of RNA polymerase II transcription preinitiation complex assembly 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.