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ONTOLOGY REPORT - ANNOTATIONS


Term:long-term synaptic depression
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Accession:GO:0060292 term browser browse the term
Definition:A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
Synonyms:broad_synonym: long term depression
 related_synonym: LTD


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long-term synaptic depression term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase JBrowse link 15 18,647,903 18,695,133 RGD:1624291
G Arf1 ADP-ribosylation factor 1 JBrowse link 10 45,562,700 45,579,214 RGD:8553918
G Cd38 CD38 molecule JBrowse link 14 71,714,768 71,754,990 RGD:2307271
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:1624291
RGD:1600115
G Drd5 dopamine receptor D5 JBrowse link 14 77,220,579 77,222,006 RGD:1624291
RGD:1600115
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:1624291
RGD:1600115
G Grid2ip Grid2 interacting protein JBrowse link 12 13,221,334 13,257,365 RGD:1624291
G Mgll monoglyceride lipase JBrowse link 4 120,671,436 120,773,458 RGD:1624291
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:8554238
G Plk2 polo-like kinase 2 JBrowse link 2 41,911,143 41,916,901 RGD:7241548
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:4144068
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:10041066
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:1624291
RGD:1600115
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1624291
G Slc24a1 solute carrier family 24 member 1 JBrowse link 8 70,409,683 70,438,352 RGD:13792537
G Slc24a2 solute carrier family 24 member 2 JBrowse link 5 105,336,287 105,579,959 RGD:1624291
RGD:13792537
G Sorcs2 sortilin-related VPS10 domain containing receptor 2 JBrowse link 14 79,538,911 79,912,333 RGD:1624291
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:1624291
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:1624291
negative regulation of long-term synaptic depression term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:1624291
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1624291
RGD:1600115
positive regulation of long-term synaptic depression term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy8 adenylate cyclase 8 JBrowse link 7 105,353,883 105,593,372 RGD:1600115
RGD:1624291
G Cbln1 cerebellin 1 precursor JBrowse link 19 20,607,507 20,611,316 RGD:1624291
G Grid2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 4 94,068,112 95,476,864 RGD:1600115
RGD:1624291
G Iqsec2 IQ motif and Sec7 domain ArfGEF 2 JBrowse link X 22,212,137 22,293,810 RGD:11049506
G Kcnb1 potassium voltage-gated channel subfamily B member 1 JBrowse link 3 163,850,785 163,935,610 RGD:1600115
RGD:1624291
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:10412705
G Pirb paired Ig-like receptor B JBrowse link 1 64,074,097 64,081,568 RGD:1624291
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A JBrowse link 4 29,976,485 30,247,371 RGD:10002752
G Stau2 staufen double-stranded RNA binding protein 2 JBrowse link 5 2,257,910 2,497,429 RGD:10043164
regulation of long-term synaptic depression term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:1600115
RGD:1624291
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:12793033
G Dgki diacylglycerol kinase, iota JBrowse link 4 64,365,115 64,831,473 RGD:1624291
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1624291
RGD:7349315
G Sorcs3 sortilin-related VPS10 domain containing receptor 3 JBrowse link 1 267,986,305 268,620,331 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological quality 4252
        regulation of synaptic plasticity 338
          long-term synaptic depression 35
            negative regulation of long-term synaptic depression 3
            positive regulation of long-term synaptic depression 9
            regulation of long-term synaptic depression + 17
Path 2
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      cell communication 7631
        cell-cell signaling 1794
          synaptic signaling 913
            trans-synaptic signaling 885
              anterograde trans-synaptic signaling 876
                chemical synaptic transmission 876
                  modulation of chemical synaptic transmission 663
                    regulation of synaptic plasticity 338
                      long-term synaptic depression 35
                        negative regulation of long-term synaptic depression 3
                        positive regulation of long-term synaptic depression 9
                        regulation of long-term synaptic depression + 17
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.