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ONTOLOGY REPORT - ANNOTATIONS


Term:long-term synaptic depression
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Accession:GO:0060292 term browser browse the term
Definition:A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
Synonyms:broad_synonym: long term depression
 related_synonym: LTD


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long-term synaptic depression term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABHD6 abhydrolase domain containing 6, acylglycerol lipase JBrowse link 13 39,982,536 40,055,467 RGD:14298760
G ARF1 ADP ribosylation factor 1 JBrowse link 2 51,219,597 51,237,640 RGD:9068941
G CD38 CD38 molecule JBrowse link 8 11,083,682 11,130,783 RGD:9068941
G DRD1 dopamine receptor D1 JBrowse link 16 49,189,555 49,193,722 RGD:14298760
G DRD5 dopamine receptor D5 JBrowse link 8 6,180,221 6,182,575 RGD:14298760
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 16 69,332,786 69,654,366 RGD:14298760
G GRID2IP Grid2 interacting protein JBrowse link 3 4,667,282 4,699,821 RGD:9068941
G MGLL monoglyceride lipase JBrowse link 13 72,480,395 72,568,964 RGD:9068941
G PICK1 protein interacting with PRKCA 1 JBrowse link 5 9,808,444 9,829,677 RGD:9068941
G PLK2 polo like kinase 2 JBrowse link 16 37,299,116 37,305,114 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 14 99,929,590 100,021,619 RGD:9068941
G PTK2B protein tyrosine kinase 2 beta JBrowse link 14 11,063,662 11,194,196 RGD:9068941
G SHANK2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 2 2,517,853 3,016,959 RGD:14298760
G SHANK3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 5 41,376 93,033 RGD:9068941
G SLC24A1 solute carrier family 24 member 1 JBrowse link 1 163,603,223 163,662,071 RGD:14298760
G SLC24A2 solute carrier family 24 member 2 JBrowse link 1 203,059,563 203,336,442 RGD:14298760
G SORCS2 sortilin related VPS10 domain containing receptor 2 JBrowse link 8 3,207,087 3,715,002 RGD:14298760
G SRF serum response factor JBrowse link 7 38,213,300 38,223,686 RGD:14298760
G STXBP1 syntaxin binding protein 1 JBrowse link 1 268,116,124 268,205,805 RGD:14298760
negative regulation of long-term synaptic depression term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADORA1 adenosine A1 receptor JBrowse link 9 113,835,279 113,875,899 RGD:14298760
G AGER advanced glycosylation end-product specific receptor JBrowse link 7 24,218,116 24,221,162 RGD:9068941
G FMR1 FMRP translational regulator 1 JBrowse link X 120,361,232 120,400,282 RGD:9068941
positive regulation of long-term synaptic depression term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADCY8 adenylate cyclase 8 JBrowse link 4 9,645,398 9,867,065 RGD:14298760
G CBLN1 cerebellin 1 precursor JBrowse link 6 35,516,097 35,518,080 RGD:14298760
G GRID2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 8 125,821,195 127,130,617 RGD:14298760
G IQSEC2 IQ motif and Sec7 domain ArfGEF 2 JBrowse link X 46,011,386 46,094,978 RGD:9068941
G KCNB1 potassium voltage-gated channel subfamily B member 1 JBrowse link 17 51,032,163 51,152,566 RGD:14298760
G MAPT microtubule associated protein tau JBrowse link 12 17,098,259 17,211,483 RGD:9068941
G PPP1R9A protein phosphatase 1 regulatory subunit 9A JBrowse link 9 74,635,285 74,944,050 RGD:9068941
G STAU2 staufen double-stranded RNA binding protein 2 JBrowse link 4 62,139,456 62,455,509 RGD:9068941
regulation of long-term synaptic depression term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARC activity regulated cytoskeleton associated protein JBrowse link 4 1,517,986 1,521,403 RGD:14298760
G BCL2L1 BCL2 like 1 JBrowse link 17 35,366,139 35,415,798 RGD:9068941
G DGKI diacylglycerol kinase iota JBrowse link 18 11,705,055 12,187,098 RGD:14298760
G SHANK3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 5 41,376 93,033 RGD:9068941
G SORCS3 sortilin related VPS10 domain containing receptor 3 JBrowse link 14 115,587,176 116,202,433 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16411
    biological regulation 11882
      regulation of biological quality 3949
        regulation of synaptic plasticity 298
          long-term synaptic depression 34
            negative regulation of long-term synaptic depression 3
            positive regulation of long-term synaptic depression 8
            regulation of long-term synaptic depression + 16
Path 2
Term Annotations click to browse term
  biological_process 16411
    cellular process 15624
      cell communication 6485
        cell-cell signaling 1681
          synaptic signaling 843
            trans-synaptic signaling 815
              anterograde trans-synaptic signaling 807
                chemical synaptic transmission 807
                  modulation of chemical synaptic transmission 611
                    regulation of synaptic plasticity 298
                      long-term synaptic depression 34
                        negative regulation of long-term synaptic depression 3
                        positive regulation of long-term synaptic depression 8
                        regulation of long-term synaptic depression + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.