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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of sarcomere organization
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Accession:GO:0060297 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
Synonyms:exact_synonym: regulation of sarcomere organisation


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regulation of sarcomere organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 ISO
ISS
(MGI:MGI:5308772|PMID:20139090)
GO_REF:0000024
RGD
UniProt
PMID:20139090 GO_REF:0000024, MGI:MGI:5308772 NCBI chr 1:137,089,558...137,315,272
Ensembl chr 1:137,014,272...137,315,272
JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO MGI:MGI:1097717|MGI:MGI:1861447 (MGI:MGI:3760007|PMID:17392382) RGD PMID:17392382 MGI:MGI:3760007 NCBI chr 9:43,110,980...43,117,585
Ensembl chr 9:43,112,141...43,116,521
JBrowse link
G Hdac2 histone deacetylase 2 ISO MGI:MGI:3712002 (MGI:MGI:3711360|PMID:17322895) RGD PMID:17322895 MGI:MGI:3711360 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Mef2c myocyte enhancer factor 2C ISO
IEA
(MGI:MGI:3768576|PMID:17875930)
GO_REF:0000107
RGD
Ensembl
PMID:17875930 GO_REF:0000107, MGI:MGI:3768576 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
negative regulation of sarcomere organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 ISO (PMID:12847114) RGD PMID:12847114 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:24777478 RGD:13204833 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
positive regulation of sarcomere organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 ISO
IEA
(PMID:17921333)
GO_REF:0000107
RGD
Ensembl
PMID:17921333 GO_REF:0000107 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728
JBrowse link
G Edn1 endothelin 1 ISO (PMID:12847114) RGD PMID:12847114 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Mylk3 myosin light chain kinase 3 IDA PMID:17885681 BHF-UCL PMID:17885681 RGD:8554371 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Prox1 prospero homeobox 1 ISO (MGI:MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:MGI:3830437 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      regulation of developmental process 2871
        regulation of anatomical structure morphogenesis 1130
          regulation of sarcomere organization 11
            negative regulation of sarcomere organization 2
            positive regulation of sarcomere organization 5
Path 2
Term Annotations click to browse term
  biological_process 20017
    cellular process 18791
      cellular component organization or biogenesis 6765
        cellular component organization 6509
          organelle organization 4072
            cytoskeleton organization 1447
              actin cytoskeleton organization 736
                actomyosin structure organization 210
                  myofibril assembly 70
                    sarcomere organization 49
                      regulation of sarcomere organization 11
                        negative regulation of sarcomere organization 2
                        positive regulation of sarcomere organization 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.