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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ryanodine-sensitive calcium-release channel activity
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Accession:GO:0060314 term browser browse the term
Definition:Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


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regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:7241270
RGD:1600115
RGD:1624291
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:7241270
RGD:1624291
RGD:1600115
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:7241270
RGD:1600115
RGD:1624291
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
RGD:1600115
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link 3 147,042,944 147,062,725 RGD:1624291
RGD:1600115
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
G Hrc histidine rich calcium binding protein JBrowse link 1 101,324,788 101,328,391 RGD:1624291
G Jph3 junctophilin 3 JBrowse link 19 54,553,419 54,613,477 RGD:1624291
RGD:1600115
G Jsrp1 junctional sarcoplasmic reticulum protein 1 JBrowse link 7 11,769,950 11,774,373 RGD:1624291
RGD:13792537
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:1624291
RGD:1600115
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
RGD:1600115
G Selenon selenoprotein N JBrowse link 5 152,748,497 152,765,489 RGD:1624291
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:1624291
RGD:1600115
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:1600115
RGD:1624291
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:1624291
RGD:1600115
G Casq2 calsequestrin 2 JBrowse link 2 204,512,361 204,568,643 RGD:1624291
RGD:1600115
RGD:2314601
G Clic2 chloride intracellular channel 2 JBrowse link 20 295,338 310,363 RGD:1624291
RGD:1600115
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link 3 147,042,944 147,062,725 RGD:1624291
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
RGD:1600115
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1624291
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1624291
RGD:1600115
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
RGD:1600115
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
RGD:1600115
positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap6 A-kinase anchoring protein 6 JBrowse link 6 73,553,111 73,991,992 RGD:8554839
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:1624291
RGD:1600115
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:1624291
RGD:1600115
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:1624291
RGD:1600115
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1624291
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1624291
RGD:1600115
G Jph2 junctophilin 2 JBrowse link 3 159,709,998 159,776,536 RGD:1624291
RGD:1600115
G Trdn triadin JBrowse link 1 25,403,390 25,787,664 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17941
    cellular process 16091
      regulation of cellular process 11307
        regulation of calcium ion transport into cytosol 113
          regulation of release of sequestered calcium ion into cytosol 87
            regulation of ryanodine-sensitive calcium-release channel activity 21
              negative regulation of ryanodine-sensitive calcium-release channel activity 11
              positive regulation of ryanodine-sensitive calcium-release channel activity 8
Path 2
Term Annotations click to browse term
  biological_process 17941
    biological regulation 12628
      regulation of biological quality 4130
        homeostatic process 1966
          chemical homeostasis 1258
            ion homeostasis 841
              cellular ion homeostasis 690
                cellular cation homeostasis 677
                  cellular metal ion homeostasis 618
                    cellular calcium ion homeostasis 506
                      regulation of cytosolic calcium ion concentration 410
                        positive regulation of cytosolic calcium ion concentration 355
                          calcium ion transport into cytosol 176
                            calcium ion transmembrane import into cytosol 152
                              release of sequestered calcium ion into cytosol 133
                                regulation of release of sequestered calcium ion into cytosol 87
                                  regulation of ryanodine-sensitive calcium-release channel activity 21
                                    negative regulation of ryanodine-sensitive calcium-release channel activity 11
                                    positive regulation of ryanodine-sensitive calcium-release channel activity 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.