Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of ryanodine-sensitive calcium-release channel activity
go back to main search page
Accession:GO:0060315 term browser browse the term
Definition:Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


show annotations for term's descendants           Sort by:
 
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:112,160,823...112,171,754
Ensembl chr 7:112,154,880...112,171,744
JBrowse link
G CALM2 calmodulin 2 ISO (PMID:26164367) UniProtKB PMID:26164367 NCBI chr 3:93,371,765...93,386,378
Ensembl chr 3:93,372,045...93,438,068
JBrowse link
G CALM3 calmodulin 3 ISO (PMID:26164367) UniProtKB PMID:26164367 NCBI chr 6:52,506,979...52,516,704
Ensembl chr 6:52,506,674...52,516,703
JBrowse link
G CASQ2 calsequestrin 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:104,918,204...104,984,019
Ensembl chr 4:104,918,501...104,999,787
JBrowse link
G CLIC2 chloride intracellular channel 2 IEA Ensembl GO_REF:0000107 NCBI chr  X:125,546,451...125,560,059
Ensembl chr  X:125,546,467...125,570,523
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A NOT ISO (PMID:12443530) BHF-UCL PMID:12443530 NCBI chr17:33,910,047...33,935,212 JBrowse link
G FKBP1B FKBP prolyl isomerase 1B IEA Ensembl GO_REF:0000107 NCBI chr 3:114,623,529...114,636,200
Ensembl chr 3:114,623,529...114,634,628
JBrowse link
G GSTO1 glutathione S-transferase omega 1 ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel IEA Ensembl GO_REF:0000107 NCBI chr 8:131,002,973...131,058,932
Ensembl chr 8:131,005,407...131,058,932
JBrowse link
G SRI sorcin IEA Ensembl GO_REF:0000107 NCBI chr 9:68,492,235...68,515,247
Ensembl chr 9:68,493,008...68,515,322
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    cellular process 15777
      negative regulation of cellular process 4868
        negative regulation of calcium ion transport into cytosol 20
          negative regulation of release of sequestered calcium ion into cytosol 16
            negative regulation of ryanodine-sensitive calcium-release channel activity 10
Path 2
Term Annotations click to browse term
  biological_process 16545
    biological regulation 12011
      regulation of biological quality 3986
        homeostatic process 1962
          chemical homeostasis 1249
            ion homeostasis 828
              cellular ion homeostasis 673
                cellular cation homeostasis 660
                  cellular metal ion homeostasis 592
                    cellular calcium ion homeostasis 480
                      regulation of cytosolic calcium ion concentration 379
                        positive regulation of cytosolic calcium ion concentration 334
                          calcium ion transport into cytosol 172
                            calcium ion transmembrane import into cytosol 149
                              release of sequestered calcium ion into cytosol 121
                                regulation of release of sequestered calcium ion into cytosol 83
                                  negative regulation of release of sequestered calcium ion into cytosol 16
                                    negative regulation of ryanodine-sensitive calcium-release channel activity 10
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.