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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of ryanodine-sensitive calcium-release channel activity
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Accession:GO:0060316 term browser browse the term
Definition:Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


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positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 IDA PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Calm1 calmodulin 1 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO
IEA
(PMID:17023043)
GO_REF:0000107
RGD
Ensembl
PMID:17023043 GO_REF:0000107 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:210,720,719...210,726,179
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO
IEA
(PMID:11035031)
GO_REF:0000107
RGD
Ensembl
PMID:11035031 GO_REF:0000107 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Jph2 junctophilin 2 ISO (PMID:20095964) RGD PMID:20095964 NCBI chr 3:159,709,998...159,776,536
Ensembl chr 3:159,712,325...159,775,643
JBrowse link
G Trdn triadin ISO
IBA
(PMID:15041652), (PMID:15731460)
PMID:21873635
RGD PMID:15041652, PMID:15731460, PMID:21873635 RGD:13792537 NCBI chr 1:25,403,390...25,787,664
Ensembl chr 1:25,403,390...25,839,345
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      positive regulation of cellular process 6149
        positive regulation of calcium ion transport into cytosol 70
          positive regulation of release of sequestered calcium ion into cytosol 47
            positive regulation of ryanodine-sensitive calcium-release channel activity 9
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological quality 4280
        homeostatic process 2077
          chemical homeostasis 1334
            ion homeostasis 887
              cellular ion homeostasis 730
                cellular cation homeostasis 717
                  cellular metal ion homeostasis 649
                    cellular calcium ion homeostasis 515
                      regulation of cytosolic calcium ion concentration 412
                        positive regulation of cytosolic calcium ion concentration 361
                          calcium ion transport into cytosol 176
                            calcium ion transmembrane import into cytosol 152
                              release of sequestered calcium ion into cytosol 127
                                regulation of release of sequestered calcium ion into cytosol 88
                                  positive regulation of release of sequestered calcium ion into cytosol 47
                                    positive regulation of ryanodine-sensitive calcium-release channel activity 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.