Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of type I interferon-mediated signaling pathway
go back to main search page
Accession:GO:0060338 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
Synonyms:exact_synonym: regulation of type I interferon-mediated signalling pathway


show annotations for term's descendants           Sort by:
 
regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone ISO
IEA
(PMID:16280321)
GO_REF:0000107
RGD
Ensembl
PMID:16280321 GO_REF:0000107 NCBI chr 8:22,160,922...22,173,797
Ensembl chr 8:22,154,067...22,173,804
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO (PMID:16280321) RGD PMID:16280321 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific ISO
IEA
MGI:MGI:3828307 (MGI:MGI:3821394|PMID:19060901)
GO_REF:0000107
RGD
Ensembl
PMID:19060901 GO_REF:0000107, MGI:MGI:3821394 NCBI chr 2:189,045,551...189,085,448
Ensembl chr 2:189,062,443...189,083,236
JBrowse link
G Cactin cactin, spliceosome C complex subunit ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:11,258,526...11,266,509
Ensembl chr 7:11,261,201...11,266,630
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 ISO (PMID:23386060) RGD PMID:23386060 NCBI chr16:54,899,452...54,918,616
Ensembl chr16:54,899,452...54,918,613
JBrowse link
G Dcst1 DC-STAMP domain containing 1 ISO (PMID:27782195) RGD PMID:27782195 NCBI chr 2:188,672,549...188,690,004
Ensembl chr 2:188,672,405...188,689,392
JBrowse link
G Mettl3 methyltransferase-like 3 ISO (PMID:30559377) RGD PMID:30559377 NCBI chr15:28,710,299...28,721,491
Ensembl chr15:28,710,300...28,721,127
JBrowse link
G Mmp12 matrix metallopeptidase 12 IEA
ISO
GO_REF:0000107
(MGI:MGI:5583923|PMID:24784232)
Ensembl
RGD
PMID:24784232 GO_REF:0000107, MGI:MGI:5583923 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:156,855,105...156,864,517
Ensembl chr 5:156,850,206...156,864,517
JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 ISO
IBA
(PMID:20434986)
PMID:21873635
(MGI:MGI:4454346|PMID:20434986)
RGD PMID:20434986, PMID:21873635 MGI:MGI:4454346, RGD:13792537 NCBI chr19:10,904,381...11,006,202
Ensembl chr19:10,905,542...10,976,396
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO
ISS
(PMID:11909529)
(MGI:MGI:3691503|PMID:11909529), (MGI:MGI:5493216|PMID:12138178)
GO_REF:0000024
RGD
UniProt
PMID:11909529, PMID:12138178 GO_REF:0000024, MGI:MGI:3691503, MGI:MGI:5493216 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 ISO (PMID:29670289)
(MGI:MGI:5521417|PMID:23972988)
RGD PMID:23972988, PMID:29670289 MGI:MGI:5521417 NCBI chr 3:153,210,829...153,250,705
Ensembl chr 3:153,210,829...153,250,641
JBrowse link
G Trex1 three prime repair exonuclease 1 ISO MGI:MGI:3052754 (MGI:MGI:3834787|PMID:18724932) RGD PMID:18724932 MGI:MGI:3834787 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 ISO (PMID:28011935) RGD PMID:28011935 NCBI chr 7:124,472,758...124,491,004
Ensembl chr 7:124,472,758...124,491,004
JBrowse link
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 ISO (PMID:30559377) RGD PMID:30559377 NCBI chr 5:150,364,490...150,390,173
Ensembl chr 5:150,365,101...150,390,099
JBrowse link
G Ythdf3 YTH N(6)-methyladenosine RNA binding protein 3 ISO (MGI:MGI:6316470|PMID:30591559) RGD PMID:30591559 MGI:MGI:6316470 NCBI chr 2:100,677,388...100,711,365
Ensembl chr 2:100,677,411...100,710,417
JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain ISO (PMID:21109225) RGD PMID:21109225 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon ISO (MGI:MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:MGI:5792628 NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394
JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:MGI:3718275|PMID:17618271) RGD PMID:17618271 MGI:MGI:3718275 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Irf7 interferon regulatory factor 7 ISO (MGI:MGI:3718275|PMID:17618271) RGD PMID:17618271 MGI:MGI:3718275 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor ISO (MGI:MGI:5432265|PMID:22745163) RGD PMID:22745163 MGI:MGI:5432265 NCBI chr 1:90,200,866...90,246,292
Ensembl chr 1:90,200,876...90,246,297
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO (PMID:16127453), (PMID:20451243) RGD PMID:16127453, PMID:20451243 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Mmp12 matrix metallopeptidase 12 IEA
ISO
GO_REF:0000107
(MGI:MGI:5583923|PMID:24784232)
Ensembl
RGD
PMID:24784232 GO_REF:0000107, MGI:MGI:5583923 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 ISO (PMID:20061403) RGD PMID:20061403 NCBI chr19:10,904,381...11,006,202
Ensembl chr19:10,905,542...10,976,396
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO (MGI:MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:MGI:5792628 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Trim6 tripartite motif containing 6 ISO (PMID:24882218)
(MGI:MGI:5645191|PMID:24882218)
RGD PMID:24882218 MGI:MGI:5645191 NCBI chr 1:169,410,084...169,423,305
Ensembl chr 1:169,410,115...169,423,283
JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K ISO (PMID:24882218) RGD PMID:24882218 NCBI chr14:44,289,247...44,348,691
Ensembl chr14:44,289,247...44,348,691
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
(PMID:19399181)
GO_REF:0000107
RGD
Ensembl
PMID:19399181 GO_REF:0000107 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Zbp1 Z-DNA binding protein 1 ISO
IEA
IBA
(MGI:MGI:3718275|PMID:17618271)
GO_REF:0000002
PMID:21873635
RGD
InterPro
PMID:17618271, PMID:21873635 GO_REF:0000002, MGI:MGI:3718275, RGD:13792537 NCBI chr 3:171,276,062...171,292,062
Ensembl chr 3:171,276,062...171,286,537
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    cellular process 18788
      signal transduction 7016
        regulation of signal transduction 2999
          regulation of cytokine-mediated signaling pathway 113
            regulation of type I interferon-mediated signaling pathway 27
              negative regulation of type I interferon-mediated signaling pathway + 14
              positive regulation of type I interferon-mediated signaling pathway 13
Path 2
Term Annotations click to browse term
  biological_process 20015
    response to stimulus 10570
      response to external stimulus 3216
        response to external biotic stimulus 1707
          response to other organism 1703
            defense response to other organism 1114
              innate immune response 830
                response to type I interferon 52
                  cellular response to type I interferon 47
                    type I interferon signaling pathway 45
                      regulation of type I interferon-mediated signaling pathway 27
                        negative regulation of type I interferon-mediated signaling pathway + 14
                        positive regulation of type I interferon-mediated signaling pathway 13
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.