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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060339 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
Synonyms:exact_synonym: negative regulation of type I interferon-mediated signalling pathway


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negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 2 189,045,551 189,085,448 RGD:1624291
RGD:1600115
G Cactin cactin, spliceosome C complex subunit JBrowse link 7 11,258,526 11,266,509 RGD:1624291
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 16 54,899,452 54,918,616 RGD:1624291
G Dcst1 DC-STAMP domain containing 1 JBrowse link 2 188,672,549 188,690,004 RGD:1624291
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1624291
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:1600115
RGD:1624291
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 5 156,855,105 156,864,517 RGD:1624291
G Nlrc5 NLR family, CARD domain containing 5 JBrowse link 19 10,904,381 11,006,202 RGD:1624291
RGD:13792537
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 JBrowse link 3 153,210,829 153,250,705 RGD:1624291
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
G Ttll12 tubulin tyrosine ligase like 12 JBrowse link 7 124,472,758 124,491,004 RGD:1624291
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 JBrowse link 5 150,364,490 150,390,173 RGD:1624291
G Ythdf3 YTH N(6)-methyladenosine RNA binding protein 3 JBrowse link 2 100,677,388 100,711,365 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cellular process 17241
      signal transduction 6872
        negative regulation of signal transduction 1213
          negative regulation of cytokine-mediated signaling pathway 54
            negative regulation of type I interferon-mediated signaling pathway 14
              suppression by virus of host type I interferon-mediated signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 19336
    response to stimulus 10395
      response to biotic stimulus 1602
        response to external biotic stimulus 1569
          response to other organism 1565
            defense response to other organism 984
              innate immune response 693
                response to type I interferon 49
                  cellular response to type I interferon 44
                    type I interferon signaling pathway 42
                      regulation of type I interferon-mediated signaling pathway 27
                        negative regulation of type I interferon-mediated signaling pathway 14
                          suppression by virus of host type I interferon-mediated signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.