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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060340 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
Synonyms:exact_synonym: positive regulation of type I interferon-mediated signalling pathway


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positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain ISO (PMID:21109225) RGD PMID:21109225 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon ISO (MGI:MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:MGI:5792628 NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394
JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:MGI:3718275|PMID:17618271) RGD PMID:17618271 MGI:MGI:3718275 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Irf7 interferon regulatory factor 7 ISO (MGI:MGI:3718275|PMID:17618271) RGD PMID:17618271 MGI:MGI:3718275 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor ISO (MGI:MGI:5432265|PMID:22745163) RGD PMID:22745163 MGI:MGI:5432265 NCBI chr 1:90,200,866...90,246,292
Ensembl chr 1:90,200,876...90,246,297
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO (PMID:16127453), (PMID:20451243) RGD PMID:16127453, PMID:20451243 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Mmp12 matrix metallopeptidase 12 IEA
ISO
GO_REF:0000107
(MGI:MGI:5583923|PMID:24784232)
Ensembl
RGD
PMID:24784232 GO_REF:0000107, MGI:MGI:5583923 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 ISO (PMID:20061403) RGD PMID:20061403 NCBI chr19:10,904,381...11,006,202
Ensembl chr19:10,905,542...10,976,396
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO (MGI:MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:MGI:5792628 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Trim6 tripartite motif containing 6 ISO (PMID:24882218)
(MGI:MGI:5645191|PMID:24882218)
RGD PMID:24882218 MGI:MGI:5645191 NCBI chr 1:169,410,084...169,423,305
Ensembl chr 1:169,410,115...169,423,283
JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K ISO (PMID:24882218) RGD PMID:24882218 NCBI chr14:44,289,247...44,348,691
Ensembl chr14:44,289,247...44,348,691
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
(PMID:19399181)
GO_REF:0000107
RGD
Ensembl
PMID:19399181 GO_REF:0000107 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Zbp1 Z-DNA binding protein 1 ISO
IEA
IBA
(MGI:MGI:3718275|PMID:17618271)
GO_REF:0000002
PMID:21873635
RGD
InterPro
PMID:17618271, PMID:21873635 GO_REF:0000002, MGI:MGI:3718275, RGD:13792537 NCBI chr 3:171,276,062...171,292,062
Ensembl chr 3:171,276,062...171,286,537
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    cellular process 18791
      signal transduction 7015
        positive regulation of signal transduction 1682
          positive regulation of cytokine-mediated signaling pathway 47
            positive regulation of type I interferon-mediated signaling pathway 13
Path 2
Term Annotations click to browse term
  biological_process 20017
    response to stimulus 10569
      response to biotic stimulus 1739
        response to external biotic stimulus 1707
          response to other organism 1703
            defense response to other organism 1114
              innate immune response 830
                response to type I interferon 52
                  cellular response to type I interferon 47
                    type I interferon signaling pathway 45
                      regulation of type I interferon-mediated signaling pathway 27
                        positive regulation of type I interferon-mediated signaling pathway 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.