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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060340 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
Synonyms:exact_synonym: positive regulation of type I interferon-mediated signalling pathway


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positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain ISO (PMID:21109225) UniProtKB PMID:21109225 NCBI chr11:65,300,889...65,305,020 JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon ISO (MGI:MGI:5792628|PMID:27129230) UniProt PMID:27129230 MGI:MGI:5792628 NCBI chr 1:182,070,565...182,096,797
Ensembl chr 1:186,351,807...186,377,971
JBrowse link
G IRF3 interferon regulatory factor 3 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chr19:46,674,193...46,680,464
Ensembl chr19:55,593,627...55,599,903
JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor ISO (MGI:MGI:5432265|PMID:22745163) MGI PMID:22745163 MGI:MGI:5432265 NCBI chr19:31,099,211...31,159,930 JBrowse link
G MAVS mitochondrial antiviral signaling protein ISO (PMID:16127453), (PMID:20451243) BHF-UCL PMID:16127453, PMID:20451243 NCBI chr20:3,885,044...3,903,554
Ensembl chr20:3,659,559...3,701,089
JBrowse link
G MMP12 matrix metallopeptidase 12 ISO (MGI:MGI:5583923|PMID:24784232) CAFA PMID:24784232 MGI:MGI:5583923 NCBI chr11:97,809,644...97,822,063
Ensembl chr11:101,294,475...101,306,762
JBrowse link
G NLRC5 NLR family CARD domain containing 5 ISO (PMID:20061403) UniProtKB PMID:20061403 NCBI chr16:37,267,541...37,361,369
Ensembl chr16:56,433,204...56,494,027
JBrowse link
G TBK1 TANK binding kinase 1 ISO (MGI:MGI:5792628|PMID:27129230) UniProt PMID:27129230 MGI:MGI:5792628 NCBI chr12:24,419,271...24,469,164
Ensembl chr12:24,917,246...24,968,587
JBrowse link
G TRIM6 tripartite motif containing 6 ISO (MGI:MGI:5645191|PMID:24882218)
(PMID:24882218)
UniProtKB PMID:24882218 MGI:MGI:5645191 NCBI chr11:5,731,256...5,748,057 JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K ISO (PMID:24882218) UniProtKB PMID:24882218 NCBI chr 4:34,026,942...34,111,923
Ensembl chr 4:39,877,966...39,960,397
JBrowse link
G WNT5A Wnt family member 5A ISO (PMID:19399181) BHF-UCL PMID:19399181 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
G ZBP1 Z-DNA binding protein 1 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chr20:53,944,224...53,961,362
Ensembl chr20:55,222,405...55,239,130
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12527
    cellular process 11621
      signal transduction 3808
        positive regulation of signal transduction 1493
          positive regulation of cytokine-mediated signaling pathway 42
            positive regulation of type I interferon-mediated signaling pathway 12
Path 2
Term Annotations click to browse term
  biological_process 12527
    response to stimulus 6722
      response to biotic stimulus 1228
        response to external biotic stimulus 1195
          response to other organism 1192
            defense response to other organism 690
              innate immune response 412
                response to type I interferon 42
                  cellular response to type I interferon 37
                    type I interferon signaling pathway 35
                      regulation of type I interferon-mediated signaling pathway 26
                        positive regulation of type I interferon-mediated signaling pathway 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.