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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060340 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
Synonyms:exact_synonym: positive regulation of type I interferon-mediated signalling pathway


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positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain ISO (PMID:21109225) UniProtKB PMID:21109225 NCBI chrNW_004955422:16,026,323...16,035,808 JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon ISO (MGI:MGI:5792628|PMID:27129230) UniProt PMID:27129230 MGI:MGI:5792628 NCBI chrNW_004955406:42,056,014...42,077,701 JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chrNW_004955559:1,223,986...1,228,671 JBrowse link
G Irf7 interferon regulatory factor 7 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chrNW_004955476:11,442,781...11,445,706 JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor ISO (MGI:MGI:5432265|PMID:22745163) MGI PMID:22745163 MGI:MGI:5432265 NCBI chrNW_004955468:3,799,897...3,863,241 JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO (PMID:16127453), (PMID:20451243) BHF-UCL PMID:16127453, PMID:20451243 NCBI chrNW_004955415:14,691,918...14,704,782 JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO (MGI:MGI:5583923|PMID:24784232) CAFA PMID:24784232 MGI:MGI:5583923 NCBI chrNW_004955412:6,045,146...6,057,112 JBrowse link
G Nlrc5 NLR family CARD domain containing 5 ISO (PMID:20061403) UniProtKB PMID:20061403 NCBI chrNW_004955433:14,670,273...14,752,739 JBrowse link
G Tbk1 TANK binding kinase 1 ISO (MGI:MGI:5792628|PMID:27129230) UniProt PMID:27129230 MGI:MGI:5792628 NCBI chrNW_004955458:11,210,120...11,263,632 JBrowse link
G Trim6 tripartite motif containing 6 ISO (MGI:MGI:5645191|PMID:24882218)
(PMID:24882218)
UniProtKB PMID:24882218 MGI:MGI:5645191 NCBI chrNW_004955414:21,495,593...21,513,703 JBrowse link
G Ube2k ubiquitin conjugating enzyme E2 K ISO (PMID:24882218) UniProtKB PMID:24882218 NCBI chrNW_004955443:7,618,379...7,655,542 JBrowse link
G Wnt5a Wnt family member 5A ISO (PMID:19399181) BHF-UCL PMID:19399181 NCBI chrNW_004955430:5,304,817...5,325,684 JBrowse link
G Zbp1 Z-DNA binding protein 1 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chrNW_004955445:1,867,436...1,878,132 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11860
    cellular process 11055
      signal transduction 3672
        positive regulation of signal transduction 1439
          positive regulation of cytokine-mediated signaling pathway 43
            positive regulation of type I interferon-mediated signaling pathway 13
Path 2
Term Annotations click to browse term
  biological_process 11860
    response to stimulus 6354
      response to biotic stimulus 1079
        response to external biotic stimulus 1046
          response to other organism 1043
            defense response to other organism 582
              innate immune response 354
                response to type I interferon 42
                  cellular response to type I interferon 36
                    type I interferon signaling pathway 35
                      regulation of type I interferon-mediated signaling pathway 27
                        positive regulation of type I interferon-mediated signaling pathway 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.