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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060340 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
Synonyms:exact_synonym: positive regulation of type I interferon-mediated signalling pathway


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positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain ISO (PMID:21109225) UniProtKB PMID:21109225 NCBI chr18:48,087,447...48,094,497 JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon IEA Ensembl GO_REF:0000107 NCBI chr38:2,747,303...2,772,574
Ensembl chr38:2,747,297...2,772,587
JBrowse link
G IRF3 interferon regulatory factor 3 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065
JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor IEA Ensembl GO_REF:0000107 NCBI chr 1:118,061,854...118,117,493
Ensembl chr 1:118,063,512...118,117,478
JBrowse link
G MAVS mitochondrial antiviral signaling protein IEA Ensembl GO_REF:0000107 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807
JBrowse link
G MMP12 matrix metallopeptidase 12 IEA Ensembl GO_REF:0000107 NCBI chr 5:28,918,626...28,933,404
Ensembl chr 5:28,918,594...28,933,309
JBrowse link
G NLRC5 NLR family CARD domain containing 5 IEA Ensembl GO_REF:0000107 NCBI chr 2:59,279,535...59,359,327
Ensembl chr 2:59,280,390...59,338,931
JBrowse link
G TBK1 TANK binding kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr10:7,169,664...7,208,890
Ensembl chr10:7,168,007...7,208,899
JBrowse link
G TRIM6 tripartite motif containing 6 IEA Ensembl GO_REF:0000107 NCBI chr21:28,595,887...28,611,562
Ensembl chr21:28,595,448...28,611,124
JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K IEA Ensembl GO_REF:0000107 NCBI chr 3:72,713,035...72,780,199
Ensembl chr 3:72,717,236...72,780,210
JBrowse link
G WNT5A Wnt family member 5A ISS UniProtKB GO_REF:0000024 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
G ZBP1 Z-DNA binding protein 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:42,583,674...42,589,857
Ensembl chr24:42,584,083...42,589,753
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    cellular process 15440
      signal transduction 5450
        positive regulation of signal transduction 1592
          positive regulation of cytokine-mediated signaling pathway 44
            positive regulation of type I interferon-mediated signaling pathway 12
Path 2
Term Annotations click to browse term
  biological_process 16162
    response to stimulus 8537
      response to biotic stimulus 1417
        response to external biotic stimulus 1385
          response to other organism 1381
            defense response to other organism 814
              innate immune response 552
                response to type I interferon 47
                  cellular response to type I interferon 41
                    type I interferon signaling pathway 37
                      regulation of type I interferon-mediated signaling pathway 26
                        positive regulation of type I interferon-mediated signaling pathway 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.