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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060340 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
Synonyms:exact_synonym: positive regulation of type I interferon-mediated signalling pathway


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positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain IMP (PMID:21109225) UniProtKB PMID:21109225 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,163...70,207,390
Ensembl chr11:70,203,163...70,207,390
JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon IEA Ensembl GO_REF:0000107 NCBI chr 1:206,470,243...206,496,890
Ensembl chr 1:206,470,476...206,496,889
JBrowse link
G IRF3 interferon regulatory factor 3 IEA Ensembl GO_REF:0000107 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF7 interferon regulatory factor 7 IEA Ensembl GO_REF:0000107 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor IEA Ensembl GO_REF:0000107 NCBI chr19:34,172,499...34,229,288
Ensembl chr19:34,172,504...34,229,515
JBrowse link
G MAVS mitochondrial antiviral signaling protein IDA (PMID:16127453), (PMID:20451243) BHF-UCL PMID:16127453, PMID:20451243 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
JBrowse link
G MMP12 matrix metallopeptidase 12 IEA Ensembl GO_REF:0000107 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G NLRC5 NLR family CARD domain containing 5 IDA (PMID:20061403) UniProtKB PMID:20061403 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531
JBrowse link
G TBK1 TANK binding kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TRIM6 tripartite motif containing 6 IMP (PMID:24882218) UniProtKB PMID:24882218 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958
JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K IMP (PMID:24882218) UniProtKB PMID:24882218 NCBI chr 4:39,698,136...39,782,792
Ensembl chr 4:39,698,109...39,782,792
JBrowse link
G WNT5A Wnt family member 5A IDA (PMID:19399181) BHF-UCL PMID:19399181 NCBI chr 3:55,465,715...55,505,261
Ensembl chr 3:55,465,715...55,490,539
JBrowse link
G ZBP1 Z-DNA binding protein 1 IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr20:57,603,852...57,620,480
Ensembl chr20:57,603,846...57,620,576
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18650
    cellular process 17668
      signal transduction 6562
        positive regulation of signal transduction 1809
          positive regulation of cytokine-mediated signaling pathway 51
            positive regulation of type I interferon-mediated signaling pathway 13
Path 2
Term Annotations click to browse term
  biological_process 18650
    response to stimulus 10129
      response to biotic stimulus 1946
        response to external biotic stimulus 1911
          response to other organism 1908
            defense response to other organism 1312
              innate immune response 1072
                response to type I interferon 99
                  cellular response to type I interferon 95
                    type I interferon signaling pathway 94
                      regulation of type I interferon-mediated signaling pathway 34
                        positive regulation of type I interferon-mediated signaling pathway 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.