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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060340 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
Synonyms:exact_synonym: positive regulation of type I interferon-mediated signalling pathway


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positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain ISO (PMID:21109225) UniProtKB PMID:21109225 NCBI chrNW_004936599:633,501...639,412 JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon ISO (MGI:MGI:5792628|PMID:27129230) UniProt PMID:27129230 MGI:MGI:5792628 NCBI chrNW_004936557:6,066,207...6,090,767 JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chrNW_004936664:3,477,750...3,482,489 JBrowse link
G Irf7 interferon regulatory factor 7 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chrNW_004936888:445,340...448,801 JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor ISO (MGI:MGI:5432265|PMID:22745163) MGI PMID:22745163 MGI:MGI:5432265 NCBI chrNW_004936570:1,723,966...1,791,784 JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO (PMID:16127453), (PMID:20451243) BHF-UCL PMID:16127453, PMID:20451243 NCBI chrNW_004936485:14,842,778...14,859,163 JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO (MGI:MGI:5583923|PMID:24784232) CAFA PMID:24784232 MGI:MGI:5583923 NCBI chrNW_004936551:5,107,567...5,117,843 JBrowse link
G Nlrc5 NLR family CARD domain containing 5 ISO (PMID:20061403) UniProtKB PMID:20061403 NCBI chrNW_004936475:9,137,929...9,218,682 JBrowse link
G Tbk1 TANK binding kinase 1 ISO (MGI:MGI:5792628|PMID:27129230) UniProt PMID:27129230 MGI:MGI:5792628 NCBI chrNW_004936545:2,763,755...2,809,229 JBrowse link
G Trim6 tripartite motif containing 6 ISO (MGI:MGI:5645191|PMID:24882218)
(PMID:24882218)
UniProtKB PMID:24882218 MGI:MGI:5645191 NCBI chrNW_004937097:23,695...31,673 JBrowse link
G Ube2k ubiquitin conjugating enzyme E2 K ISO (PMID:24882218) UniProtKB PMID:24882218 NCBI chrNW_004936482:7,244,972...7,323,263 JBrowse link
G Wnt5a Wnt family member 5A ISO (PMID:19399181) BHF-UCL PMID:19399181 NCBI chrNW_004936473:6,031,627...6,052,211 JBrowse link
G Zbp1 Z-DNA binding protein 1 ISO (MGI:MGI:3718275|PMID:17618271) MGI PMID:17618271 MGI:MGI:3718275 NCBI chrNW_004936530:398,980...408,798 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11968
    cellular process 11136
      signal transduction 3695
        positive regulation of signal transduction 1445
          positive regulation of cytokine-mediated signaling pathway 42
            positive regulation of type I interferon-mediated signaling pathway 13
Path 2
Term Annotations click to browse term
  biological_process 11968
    response to stimulus 6404
      response to biotic stimulus 1085
        response to external biotic stimulus 1052
          response to other organism 1049
            defense response to other organism 586
              innate immune response 354
                response to type I interferon 40
                  cellular response to type I interferon 34
                    type I interferon signaling pathway 34
                      regulation of type I interferon-mediated signaling pathway 27
                        positive regulation of type I interferon-mediated signaling pathway 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.