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ONTOLOGY REPORT - ANNOTATIONS


Term:endochondral bone morphogenesis
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Accession:GO:0060350 term browser browse the term
Definition:The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.


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endochondral bone morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr2 bone morphogenetic protein receptor type 2 JBrowse link 9 66,568,074 66,683,019 RGD:1600115
G Carm1 coactivator-associated arginine methyltransferase 1 JBrowse link 8 22,577,723 22,622,555 RGD:1624291
G Dspp dentin sialophosphoprotein JBrowse link 14 6,926,972 6,933,079 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
cartilage development involved in endochondral bone morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:1624291
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:1624291
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:8661659
RGD:1624291
RGD:1600115
G Ghr growth hormone receptor JBrowse link 2 53,149,225 53,413,954 RGD:2307373
G Hoxa11 homeobox A11 JBrowse link 4 82,296,888 82,301,419 RGD:1624291
G Hoxd11 homeobox D11 JBrowse link 3 61,604,256 61,606,874 RGD:1624291
G Hspg2 heparan sulfate proteoglycan 2 JBrowse link 5 155,812,096 155,913,751 RGD:1624291
G Shox2 short stature homeobox 2 JBrowse link 2 164,118,175 164,126,783 RGD:1624291
G Sik3 SIK family kinase 3 JBrowse link 8 50,310,263 50,520,284 RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
chondrocyte development involved in endochondral bone morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Serpinh1 serpin family H member 1 JBrowse link 1 164,301,010 164,308,306 RGD:1624291
RGD:1600115
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:1600115
chondrocyte differentiation involved in endochondral bone morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:1624291
RGD:1600115
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 JBrowse link 1 174,428,056 174,495,356 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Trip11 thyroid hormone receptor interactor 11 JBrowse link 6 125,741,520 125,812,926 RGD:1624291
endochondral ossification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:1624291
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:1624291
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 JBrowse link 17 90,191,119 90,218,013 RGD:1624291
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:1624291
G Col10a1 collagen type X alpha 1 chain JBrowse link 20 41,180,295 41,190,664 RGD:704421
G Col13a1 collagen type XIII alpha 1 chain JBrowse link 20 31,456,502 31,598,360 RGD:1624291
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:1624291
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:1624291
RGD:1600115
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 JBrowse link 16 22,704,318 23,075,071 RGD:1624291
G Dlx5 distal-less homeobox 5 JBrowse link 4 32,387,741 32,392,085 RGD:1600115
RGD:1624291
G Fgf18 fibroblast growth factor 18 JBrowse link 10 18,047,109 18,082,290 RGD:1624291
RGD:1600115
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:1624291
G Hspg2 heparan sulfate proteoglycan 2 JBrowse link 5 155,812,096 155,913,751 RGD:1624291
G Ift80 intraflagellar transport 80 JBrowse link 2 165,506,878 165,600,748 RGD:1600115
RGD:1624291
G Inppl1 inositol polyphosphate phosphatase-like 1 JBrowse link 1 166,898,177 166,912,524 RGD:1600115
RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1624291
RGD:1600115
G Mef2d myocyte enhancer factor 2D JBrowse link 2 187,511,775 187,541,285 RGD:1624291
RGD:1600115
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:10043159
RGD:1624291
RGD:1600115
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:1624291
G Mmp16 matrix metallopeptidase 16 JBrowse link 5 31,568,344 31,818,368 RGD:1624291
RGD:1600115
G Nab1 Ngfi-A binding protein 1 JBrowse link 9 53,906,073 53,945,474 RGD:1624291
G Nab2 Ngfi-A binding protein 2 JBrowse link 7 70,963,580 70,971,471 RGD:1624291
G Pex7 peroxisomal biogenesis factor 7 JBrowse link 1 15,311,768 15,374,702 RGD:1624291
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 JBrowse link 10 83,635,557 83,643,862 RGD:1624291
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:1624291
RGD:1600115
G Scx scleraxis bHLH transcription factor JBrowse link 7 117,519,075 117,521,093 RGD:1624291
G Sik3 SIK family kinase 3 JBrowse link 8 50,310,263 50,520,284 RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1600115
RGD:1624291
G Tek TEK receptor tyrosine kinase JBrowse link 5 113,725,717 113,852,799 RGD:1601509
G Tmem119 transmembrane protein 119 JBrowse link 12 48,598,498 48,605,704 RGD:1624291
growth plate cartilage axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:1624291
growth plate cartilage chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col27a1 collagen type XXVII alpha 1 chain JBrowse link 5 79,054,004 79,172,442 RGD:1624291
G Poc1a POC1 centriolar protein A JBrowse link 8 114,982,764 115,050,844 RGD:1624291
growth plate cartilage chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa6 annexin A6 JBrowse link 10 40,320,581 40,375,605 RGD:13792537
G Ift80 intraflagellar transport 80 JBrowse link 2 165,506,878 165,600,748 RGD:1600115
RGD:1624291
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1624291
RGD:1600115
growth plate cartilage chondrocyte growth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
growth plate cartilage chondrocyte morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Coch cochlin JBrowse link 6 72,359,702 72,373,710 RGD:13792537
G Col12a1 collagen type XII alpha 1 chain JBrowse link 8 87,042,820 87,150,701 RGD:13792537
G Col14a1 collagen type XIV alpha 1 chain JBrowse link 7 95,054,877 95,274,073 RGD:13792537
G Col20a1 collagen type XX alpha 1 chain JBrowse link 3 176,491,292 176,526,009 RGD:13792537
G Col6a2 collagen type VI alpha 2 chain JBrowse link 20 12,773,472 12,801,179 RGD:13792537
G Col7a1 collagen type VII alpha 1 chain JBrowse link 8 117,694,441 117,726,844 RGD:13792537
G LOC100911854 mannose-binding protein C-like JBrowse link 1 248,723,370 248,730,969 RGD:13792537
G Matn1 matrilin 1 JBrowse link 5 149,077,412 149,086,957 RGD:1624291
RGD:13792537
G Matn2 matrilin 2 JBrowse link 7 72,985,832 73,210,093 RGD:13792537
G Matn3 matrilin 3 JBrowse link 6 34,071,428 34,091,048 RGD:13792537
G Matn4 matrilin 4 JBrowse link 3 160,838,632 160,853,650 RGD:13792537
G Mbl1 mannose-binding lectin (protein A) 1 JBrowse link 16 18,736,154 18,742,193 RGD:13792537
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:13792537
G Vit vitrin JBrowse link 6 1,091,817 1,208,888 RGD:13792537
G Vwa1 von Willebrand factor A domain containing 1 JBrowse link 5 173,216,737 173,221,923 RGD:13792537
G Vwa2 von Willebrand factor A domain containing 2 JBrowse link 1 277,689,478 277,730,407 RGD:13792537
growth plate cartilage chondrocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cer1 cerberus 1, DAN family BMP antagonist JBrowse link 5 101,003,019 101,006,375 RGD:1624291
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1624291
RGD:1600115
growth plate cartilage development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:8661256
G Col9a1 collagen type IX alpha 1 chain JBrowse link 9 30,419,001 30,502,307 RGD:1624291
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:1600115
RGD:1624291
G Ift80 intraflagellar transport 80 JBrowse link 2 165,506,878 165,600,748 RGD:1624291
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:1624291
RGD:1600115
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:1624291
G Rarb retinoic acid receptor, beta JBrowse link 15 9,915,223 10,262,599 RGD:1624291
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
G Thbs3 thrombospondin 3 JBrowse link 2 188,528,979 188,540,738 RGD:1624291
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:1624291
negative regulation of growth plate cartilage chondrocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dspp dentin sialophosphoprotein JBrowse link 14 6,926,972 6,933,079 RGD:1624291
regulation of growth plate cartilage chondrocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Carm1 coactivator-associated arginine methyltransferase 1 JBrowse link 8 22,577,723 22,622,555 RGD:1624291
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316785

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    developmental process 6673
      anatomical structure morphogenesis 2838
        animal organ morphogenesis 1135
          bone morphogenesis 126
            endochondral bone morphogenesis 79
              cartilage development involved in endochondral bone morphogenesis + 53
              endochondral ossification 33
              perichondral bone morphogenesis 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    developmental process 6673
      anatomical structure development 6138
        multicellular organism development 5605
          system development 5126
            animal organ development 3916
              animal organ morphogenesis 1135
                skeletal system morphogenesis 273
                  bone morphogenesis 126
                    endochondral bone morphogenesis 79
                      cartilage development involved in endochondral bone morphogenesis + 53
                      endochondral ossification 33
                      perichondral bone morphogenesis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.