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ONTOLOGY REPORT - ANNOTATIONS


Term:SMAD protein signal transduction
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Accession:GO:0060395 term browser browse the term
Definition:The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.


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SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein ISO
IEA
(MGI:MGI:1195384|PMID:9420335)
GO_REF:0000107
RGD
Ensembl
PMID:9420335 GO_REF:0000107, MGI:MGI:1195384 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 ISO (PMID:24236640) RGD PMID:24236640 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517
JBrowse link
G Bmp10 bone morphogenetic protein 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728
JBrowse link
G Bmp15 bone morphogenetic protein 15 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:17,016,831...17,021,894
Ensembl chr  X:17,016,778...17,023,418
JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO
IBA
ISS
(PMID:17244894)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:17244894, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp3 bone morphogenetic protein 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:12,362,912...12,387,572
Ensembl chr14:12,359,363...12,387,102
JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO
IBA
ISS
IEA
(MGI:MGI:1195384|PMID:9420335)
PMID:21873635
GO_REF:0000024
(PMID:17244894)
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:9420335, PMID:17244894, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1195384, RGD:13792537 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp5 bone morphogenetic protein 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO
IBA
ISS
(MGI:MGI:4352622|PMID:19252488)
PMID:21873635
GO_REF:0000024
(PMID:17244894)
RGD
UniProt
PMID:17244894, PMID:19252488, PMID:21873635 GO_REF:0000024, MGI:MGI:4352622, RGD:13792537 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO
IBA
(PMID:17244894)
PMID:21873635
RGD PMID:17244894, PMID:21873635 RGD:13792537 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Bmp8a bone morphogenetic protein 8a IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:141,007,462...141,033,511
Ensembl chr 5:141,007,462...141,033,511
JBrowse link
G Bmp8b bone morphogenetic protein 8b IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:140,803,387...140,821,104
Ensembl chr 5:140,803,638...140,820,628
JBrowse link
G Btbd11 BTB domain containing 11 ISO
IBA
(MGI:MGI:5486383|PMID:23390484)
PMID:21873635
RGD PMID:23390484, PMID:21873635 MGI:MGI:5486383, RGD:13792537 NCBI chr 7:24,041,194...24,314,418
Ensembl chr 7:24,043,126...24,313,885
JBrowse link
G Cers1 ceramide synthase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:20,845,580...20,860,789
Ensembl chr16:20,845,576...20,860,789
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 ISO (PMID:9707553) RGD PMID:9707553 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO (PMID:9732876) RGD PMID:9732876 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gata4 GATA binding protein 4 ISO (MGI:MGI:1195384|PMID:9420335) RGD PMID:9420335 MGI:MGI:1195384 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gdf1 growth differentiation factor 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:20,845,580...20,860,789
Ensembl chr16:20,845,576...20,860,767
JBrowse link
G Gdf10 growth differentiation factor 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:10,250,508...10,262,383
Ensembl chr16:10,250,404...10,263,150
JBrowse link
G Gdf11 growth differentiation factor 11 ISO
IBA
ISS
(PMID:28257634)
PMID:21873635
GO_REF:0000024
(MGI:MGI:3695190|PMID:16845371)
RGD
UniProt
PMID:16845371, PMID:28257634, PMID:21873635 GO_REF:0000024, MGI:MGI:3695190, RGD:13792537 NCBI chr 7:3,306,863...3,315,856
Ensembl chr 7:3,306,863...3,315,856
JBrowse link
G Gdf15 growth differentiation factor 15 IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:25893289)
Ensembl
UniProt
RGD
PMID:25893289, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdf2 growth differentiation factor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:10,267,510...10,293,545
Ensembl chr16:10,267,482...10,273,239
JBrowse link
G Gdf3 growth differentiation factor 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:155,417,667...155,422,014
Ensembl chr 4:155,417,004...155,421,998
JBrowse link
G Gdf5 growth differentiation factor 5 ISO
IBA
(PMID:21976273), (PMID:25092592)
PMID:21873635
RGD PMID:21976273, PMID:25092592, PMID:21873635 RGD:13792537 NCBI chr 3:151,482,672...151,487,129
Ensembl chr 3:151,483,249...151,486,693
JBrowse link
G Gdf6 growth differentiation factor 6 ISO
IBA
ISS
(PMID:26643732)
PMID:21873635
GO_REF:0000024
(MGI:MGI:5751611|PMID:26774823)
RGD
UniProt
PMID:26643732, PMID:26774823, PMID:21873635 GO_REF:0000024, MGI:MGI:5751611, RGD:13792537 NCBI chr 5:23,056,345...23,072,666
Ensembl chr 5:23,056,347...23,074,599
JBrowse link
G Gdf7 growth differentiation factor 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:33,496,596...33,507,626
Ensembl chr 6:33,503,217...33,507,542
JBrowse link
G Gdf9 growth differentiation factor 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940
JBrowse link
G Hexa hexosaminidase subunit alpha ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 ISO (PMID:12874272) RGD PMID:12874272 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hnf1a HNF1 homeobox A ISO (MGI:MGI:1195384|PMID:9420335) RGD PMID:9420335 MGI:MGI:1195384 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha ISO
IEA
(MGI:MGI:1195384|PMID:9420335)
GO_REF:0000107
RGD
Ensembl
PMID:9420335 GO_REF:0000107, MGI:MGI:1195384 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Inha inhibin subunit alpha IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400
JBrowse link
G Inhba inhibin subunit beta A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inhbb inhibin subunit beta B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G Inhbc inhibin subunit beta C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:70,648,005...70,661,475
Ensembl chr 7:70,646,519...70,661,891
JBrowse link
G Inhbe inhibin subunit beta E IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Jade2 jade family PHD finger 2 ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr10:37,269,132...37,315,638
Ensembl chr10:37,270,183...37,311,625
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:9732876) RGD PMID:9732876 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Lefty1 left right determination factor 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:99,212,778...99,217,786
Ensembl chr13:99,214,389...99,217,786
JBrowse link
G Lefty2 Left-right determination factor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:99,173,484...99,178,037
Ensembl chr13:99,173,484...99,178,037
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr 1:59,289,392...59,384,540
Ensembl chr 1:59,297,294...59,347,472
Ensembl chr 1:59,297,294...59,347,472
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:1353670|PMID:10681527)
Ensembl
UniProt
RGD
PMID:10681527 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1353670 NCBI chr 4:10,995,241...12,472,423
Ensembl chr 4:10,995,234...11,610,518
JBrowse link
G Mir130a microRNA 130a ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr 3:72,141,037...72,141,124
Ensembl chr 3:72,141,037...72,141,124
JBrowse link
G Mir181c microRNA 181c ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr19:25,290,211...25,290,316
Ensembl chr19:25,290,211...25,290,316
JBrowse link
G Mir181d microRNA 181d ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr19:25,290,051...25,290,133
Ensembl chr19:25,290,051...25,290,133
JBrowse link
G Mir185 microRNA 185 ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr11:86,812,702...86,812,781
Ensembl chr11:86,812,702...86,812,781
JBrowse link
G Mir25 microRNA 25 ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr12:19,307,340...19,307,423
Ensembl chr12:19,307,340...19,307,423
JBrowse link
G Mir7-1 microRNA 7-1 ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr17:6,675,016...6,675,112
Ensembl chr17:6,675,016...6,675,112
JBrowse link
G Mstn myostatin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr 2:112,868,834...112,932,622
Ensembl chr 2:112,868,707...112,934,953
JBrowse link
G Nodal nodal growth differentiation factor ISO
IBA
(MGI:MGI:1195384|PMID:9420335)
PMID:21873635
RGD PMID:9420335, PMID:21873635 MGI:MGI:1195384, RGD:13792537 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096
JBrowse link
G Nup93 nucleoporin 93 ISO
ISS
(PMID:26878725)
GO_REF:0000024
(MGI:MGI:5787706|PMID:26878725)
RGD
UniProt
PMID:26878725 GO_REF:0000024, MGI:MGI:5787706 NCBI chr19:11,159,769...11,263,980
Ensembl chr19:11,159,774...11,263,980
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 NOT ISO (PMID:16777850) RGD PMID:16777850 NCBI chr18:73,479,863...73,524,956
Ensembl chr18:73,378,662...73,524,956
JBrowse link
G Rbm14 RNA binding motif protein 14 ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr 1:220,048,740...220,067,124
Ensembl chr 1:220,048,873...220,067,124
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 ISO MGI:MGI:2386954|MGI:MGI:3793279 (MGI:MGI:4822496|PMID:20660756) RGD PMID:20660756 MGI:MGI:4822496 NCBI chr17:11,953,552...12,134,386
Ensembl chr17:11,953,552...12,134,386
JBrowse link
G Ski SKI proto-oncogene ISO (PMID:12874272) RGD PMID:12874272 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899
JBrowse link
G Slc33a1 solute carrier family 33 member 1 ISO (PMID:25402622) RGD PMID:25402622 NCBI chr 2:154,520,170...154,542,981
Ensembl chr 2:154,520,087...154,542,919
JBrowse link
G Smad1 SMAD family member 1 ISO
IBA
IEA
UniProtKB:P20722 (MGI:MGI:4352622|PMID:19252488)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:19252488, PMID:21873635 GO_REF:0000107, MGI:MGI:4352622, RGD:13792537 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smad2 SMAD family member 2 ISO
IBA
MGI:MGI:1201674 (MGI:MGI:5486383|PMID:23390484)
PMID:21873635
RGD PMID:23390484, PMID:21873635 MGI:MGI:5486383, RGD:13792537 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 ISO
IBA
MGI:MGI:108051 (MGI:MGI:5486383|PMID:23390484)
PMID:21873635
RGD PMID:23390484, PMID:21873635 MGI:MGI:5486383, RGD:13792537 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:9707553), (PMID:9732876)
Ensembl
RGD
PMID:9707553, PMID:9732876, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smad5 SMAD family member 5 ISO
IBA
UniProtKB:P20722 (MGI:MGI:4352622|PMID:19252488)
PMID:21873635
RGD PMID:19252488, PMID:21873635 MGI:MGI:4352622, RGD:13792537 NCBI chr17:8,307,448...8,336,996
Ensembl chr17:8,311,796...8,331,032
JBrowse link
G Smad6 SMAD family member 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Smad7 SMAD family member 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Smad9 SMAD family member 9 ISO
IBA
UniProtKB:P20722 (MGI:MGI:4352622|PMID:19252488)
PMID:21873635
RGD PMID:19252488, PMID:21873635 MGI:MGI:4352622, RGD:13792537 NCBI chr 2:143,951,725...144,002,025
Ensembl chr 2:144,191,846...144,212,138
Ensembl chr 2:144,191,846...144,212,138
JBrowse link
G Stoml1 stomatin like 1 ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr 8:63,037,135...63,045,024
Ensembl chr 8:63,036,976...63,045,030
JBrowse link
G Sub1 SUB1 regulator of transcription ISO (MGI:MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:MGI:5486383 NCBI chr 2:62,019,902...62,034,704
Ensembl chr 2:62,022,567...62,034,628
JBrowse link
G Tbxt T-box transcription factor T ISO (MGI:MGI:1195384|PMID:9420335) RGD PMID:9420335 MGI:MGI:1195384 NCBI chr 1:52,887,067...52,900,691
Ensembl chr 1:52,887,067...52,894,832
JBrowse link
G Tf transferrin ISO (MGI:MGI:1195384|PMID:9420335) RGD PMID:9420335 MGI:MGI:1195384 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO
IBA
ISS
(PMID:17192487)
PMID:21873635
GO_REF:0000024
RGD
BHF-UCL
PMID:17192487, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Vim vimentin ISO
IEA
(MGI:MGI:5486383|PMID:23390484)
GO_REF:0000107
RGD
Ensembl
PMID:23390484 GO_REF:0000107, MGI:MGI:5486383 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 ISO (PMID:16777850) RGD PMID:16777850 NCBI chr16:1,749,191...1,954,633
Ensembl chr16:1,749,191...1,954,614
JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 NOT ISO (PMID:16777850) RGD PMID:16777850 NCBI chr14:86,645,875...86,662,419
Ensembl chr14:86,652,365...86,661,441
JBrowse link
negative regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn3 cellular communication network factor 3 ISO
ISS
(MGI:MGI:5504324|PMID:23653360)
GO_REF:0000024
RGD
UniProt
PMID:23653360 GO_REF:0000024, MGI:MGI:5504324 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Cilp cartilage intermediate layer protein ISO UniProtKB:P01137 (PMID:29167509) RGD PMID:29167509 NCBI chr 8:70,760,922...70,775,891
Ensembl chr 8:70,760,922...70,775,891
JBrowse link
G Fam89b family with sequence similarity 89, member B ISO
IBA
(MGI:MGI:5486566|PMID:12646588)
PMID:21873635
RGD PMID:12646588, PMID:21873635 MGI:MGI:5486566, RGD:13792537 NCBI chr 1:221,085,894...221,087,449
Ensembl chr 1:221,085,895...221,087,449
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 ISO UniProtKB:Q9Y3F4 (PMID:23687415) RGD PMID:23687415 NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663
JBrowse link
G Slc2a10 solute carrier family 2 member 10 ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:162,182,156...162,194,610
Ensembl chr 3:162,181,974...162,194,804
JBrowse link
G Ucma upper zone of growth plate and cartilage matrix associated ISO MGI:MGI:5314628 (MGI:MGI:6163471|PMID:29563538) RGD PMID:29563538 MGI:MGI:6163471 NCBI chr17:77,252,099...77,262,301
Ensembl chr17:77,252,100...77,261,731
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 ISS
ISO
IEA
GO_REF:0000024
(PMID:26039994)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:26039994 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:157,869,383...158,156,266
Ensembl chr 2:157,869,392...158,156,444
JBrowse link
positive regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO
ISS
IEA
(PMID:9389648)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:9389648 GO_REF:0000024, GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO (MGI:MGI:4352622|PMID:19252488) RGD PMID:19252488 MGI:MGI:4352622 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (PMID:9389648) RGD PMID:9389648 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Dab2 DAB adaptor protein 2 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Jak2 Janus kinase 2 ISO UniProtKB:Q5VV43 (PMID:28334068) RGD PMID:28334068 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Nodal nodal growth differentiation factor ISO (PMID:21741376) RGD PMID:21741376 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096
JBrowse link
G Nup93 nucleoporin 93 ISO
ISS
(PMID:26878725)
GO_REF:0000024
(MGI:MGI:5787706|PMID:26878725)
RGD
UniProt
PMID:26878725 GO_REF:0000024, MGI:MGI:5787706 NCBI chr19:11,159,769...11,263,980
Ensembl chr19:11,159,774...11,263,980
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor ISO (PMID:17099224) RGD PMID:17099224 NCBI chr16:61,954,569...62,109,998
Ensembl chr16:61,954,590...62,096,497
JBrowse link
G RGD1307443 similar to mKIAA0319 protein ISO UniProtKB:O60674|UniProtKB:Q9NRF2 (PMID:28334068) RGD PMID:28334068 NCBI chr17:42,163,245...42,226,725
Ensembl chr17:42,165,817...42,226,377
JBrowse link
G Sh2b1 SH2B adaptor protein 1 ISO UniProtKB:Q5VV43 (PMID:28334068) RGD PMID:28334068 NCBI chr 1:197,878,839...197,888,223
Ensembl chr 1:197,878,840...197,886,759
JBrowse link
G Smad4 SMAD family member 4 ISO
IEA
(MGI:MGI:2683382|PMID:14691138)
GO_REF:0000107
RGD
Ensembl
PMID:14691138 GO_REF:0000107, MGI:MGI:2683382 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISS
ISO
GO_REF:0000024
(PMID:19366691), (PMID:29167509), (PMID:9389648)
AgBase
RGD
PMID:9389648, PMID:19366691, PMID:29167509 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb3 transforming growth factor, beta 3 ISO (MGI:MGI:2683382|PMID:14691138) RGD PMID:14691138 MGI:MGI:2683382 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO (PMID:9389648) RGD PMID:9389648 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdf5 growth differentiation factor 5 ISO (PMID:21976273) RGD PMID:21976273 NCBI chr 3:151,482,672...151,487,129
Ensembl chr 3:151,483,249...151,486,693
JBrowse link
G Ovol2 ovo-like zinc finger 2 ISO (MGI:MGI:6284898|PMID:28455959) RGD PMID:28455959 MGI:MGI:6284898 NCBI chr 3:138,433,990...138,464,511
Ensembl chr 3:138,433,990...138,462,063
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 ISO (MGI:MGI:2449899|PMID:12543979) RGD PMID:12543979 MGI:MGI:2449899 NCBI chr14:114,517,839...114,700,199
Ensembl chr14:114,518,816...114,692,764
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
ISS
(PMID:25893292)
GO_REF:0000024
RGD
UniProt
PMID:25893292 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tob1 transducer of ErbB-2.1 ISO
IEA
(MGI:MGI:1928565|PMID:11163184)
GO_REF:0000107
RGD
Ensembl
PMID:11163184 GO_REF:0000107, MGI:MGI:1928565 NCBI chr10:81,913,689...81,915,727
Ensembl chr10:81,913,689...81,915,716
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 ISO (PMID:18568018) RGD PMID:18568018 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    signaling 7588
      signal transduction 7015
        SMAD protein signal transduction 95
          negative regulation of SMAD protein signal transduction 7
          positive regulation of SMAD protein signal transduction 16
          regulation of SMAD protein signal transduction + 28
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        regulation of cellular process 12560
          signal transduction 7015
            cell surface receptor signaling pathway 2782
              enzyme linked receptor protein signaling pathway 963
                transmembrane receptor protein serine/threonine kinase signaling pathway 383
                  SMAD protein signal transduction 95
                    negative regulation of SMAD protein signal transduction 7
                    positive regulation of SMAD protein signal transduction 16
                    regulation of SMAD protein signal transduction + 28
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.