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ONTOLOGY REPORT - ANNOTATIONS


Term:growth hormone receptor signaling pathway
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Accession:GO:0060396 term browser browse the term
Definition:The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
Synonyms:exact_synonym: growth hormone receptor signalling pathway
 related_synonym: GH receptor signaling pathway;   cellular response to growth hormone


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growth hormone receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1624291
RGD:13792537
G Ghr growth hormone receptor JBrowse link 2 53,149,225 53,413,954 RGD:1624291
RGD:13792537
RGD:8553732
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1624291
RGD:1600115
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:1624291
RGD:1600115
G Pxn paxillin JBrowse link 12 46,797,953 46,845,107 RGD:1624291
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:1624291
RGD:1600115
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:1624291
growth hormone receptor signaling pathway via JAK-STAT term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624962
RGD:1624291
RGD:1600115
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:1624291
RGD:13792537
RGD:1600115
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:1624291
RGD:13792537
RGD:1600115
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:1624291
RGD:1600115
RGD:13792537
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:13792537
negative regulation of growth hormone receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gdf15 growth differentiation factor 15 JBrowse link 16 20,555,395 20,557,978 RGD:1600115
RGD:1624291
G Leprot leptin receptor overlapping transcript JBrowse link 5 120,498,910 120,511,011 RGD:1624291
RGD:13792537
positive regulation of growth hormone receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrm1 adhesion regulating molecule 1 JBrowse link 3 175,548,181 175,552,943 RGD:1624291
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Mbd5 methyl-CpG binding domain protein 5 JBrowse link 3 33,364,812 33,504,144 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      signal transduction 6968
        cell surface receptor signaling pathway 2772
          enzyme linked receptor protein signaling pathway 956
            transmembrane receptor protein tyrosine kinase signaling pathway 603
              growth hormone receptor signaling pathway 15
                growth hormone receptor signaling pathway via JAK-STAT 5
                negative regulation of growth hormone receptor signaling pathway 2
                positive regulation of growth hormone receptor signaling pathway 3
                regulation of growth hormone receptor signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 19858
    response to stimulus 10526
      response to chemical 6306
        response to organic substance 3833
          response to organonitrogen compound 1448
            cellular response to organonitrogen compound 848
              cellular response to peptide 462
                cellular response to peptide hormone stimulus 387
                  cellular response to growth hormone stimulus 21
                    growth hormone receptor signaling pathway 15
                      growth hormone receptor signaling pathway via JAK-STAT 5
                      negative regulation of growth hormone receptor signaling pathway 2
                      positive regulation of growth hormone receptor signaling pathway 3
                      regulation of growth hormone receptor signaling pathway + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.