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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of heart growth
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Accession:GO:0060421 term browser browse the term
Definition:Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.


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positive regulation of heart growth term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta ISO (MGI:MGI:3804564|PMID:18487439) RGD PMID:18487439 MGI:MGI:3804564 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Prox1 prospero homeobox 1 ISO (MGI:MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:MGI:3830437 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
G Wt1 WT1 transcription factor ISO
ISS
(MGI:MGI:62488|PMID:8395349)
GO_REF:0000024
RGD
UniProt
PMID:8395349 GO_REF:0000024, MGI:MGI:62488 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
positive regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 ISO
IEA
(MGI:MGI:3701380|PMID:17336907)
GO_REF:0000107
RGD
Ensembl
PMID:17336907 GO_REF:0000107, MGI:MGI:3701380 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (MGI:MGI:3810850|PMID:18667463) RGD PMID:18667463 MGI:MGI:3810850 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Ccnb1 cyclin B1 IDA RGD PMID:15253691 RGD:2301353 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cdk1 cyclin-dependent kinase 1 IMP RGD PMID:15253691 RGD:2301353 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4430666|PMID:19632177)
Ensembl
UniProt
RGD
PMID:19632177 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4430666 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Fgf2 fibroblast growth factor 2 IDA
ISO
(PMID:9553078) RGD PMID:9553078, PMID:8603495 RGD:8655650 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf9 fibroblast growth factor 9 ISO MGI:MGI:95522|MGI:MGI:95523 (MGI:MGI:3527351|PMID:15621532) RGD PMID:15621532 MGI:MGI:3527351 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO
IEA
IMP
MGI:MGI:104723|MGI:MGI:95523 (MGI:MGI:3527351|PMID:15621532)
GO_REF:0000107
RGD
Ensembl
PMID:15621532, PMID:18275970 GO_REF:0000107, MGI:MGI:3527351, RGD:10402047 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO MGI:MGI:104723|MGI:MGI:95522 (MGI:MGI:3527351|PMID:15621532) RGD PMID:15621532 MGI:MGI:3527351 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Gata4 GATA binding protein 4 ISO MGI:MGI:102541 (MGI:MGI:3833786|PMID:19084512) RGD PMID:19084512 MGI:MGI:3833786 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata6 GATA binding protein 6 ISO
IEA
MGI:MGI:102541 (MGI:MGI:3833786|PMID:19084512)
GO_REF:0000107
RGD
Ensembl
PMID:19084512 GO_REF:0000107, MGI:MGI:3833786 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gli1 GLI family zinc finger 1 ISO (PMID:28583401) RGD PMID:28583401 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO MGI:MGI:2447620 (MGI:MGI:3784153|PMID:17332425) RGD PMID:17332425 MGI:MGI:3784153 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IMP RGD PMID:26884868 RGD:13800890 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO
IEA
MGI:MGI:1338024 (MGI:MGI:5288131|PMID:21768366)
GO_REF:0000107
RGD
Ensembl
PMID:21768366 GO_REF:0000107, MGI:MGI:5288131 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mef2c myocyte enhancer factor 2C IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3830899|PMID:16680724)
Ensembl
UniProt
RGD
PMID:16680724 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3830899 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Ncam1 neural cell adhesion molecule 1 IMP RGD PMID:19853610 RGD:2325979 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:4947514|PMID:20007915) RGD PMID:20007915 MGI:MGI:4947514 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nrg1 neuregulin 1 ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase ISO (PMID:21474815) RGD PMID:21474815 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:MGI:3701380 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Tbx2 T-box transcription factor 2 ISO (MGI:MGI:3039059|PMID:15042700) RGD PMID:15042700 MGI:MGI:3039059 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (MGI:MGI:3579960|PMID:15901664) RGD PMID:15901664 MGI:MGI:3579960 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Tbx5 T-box transcription factor 5 ISO
IEA
MGI:MGI:107516|MGI:MGI:95664 (MGI:MGI:3833786|PMID:19084512)
GO_REF:0000107
RGD
Ensembl
PMID:19084512 GO_REF:0000107, MGI:MGI:3833786 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (MGI:MGI:2663364|PMID:12773577) RGD PMID:12773577 MGI:MGI:2663364 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Wnt2 Wnt family member 2 ISO MGI:MGI:4361155 (MGI:MGI:4439199|PMID:20159597) RGD PMID:20159597 MGI:MGI:4439199 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420
JBrowse link
G Yap1 Yes1 associated transcriptional regulator ISO (MGI:MGI:5509071|PMID:23918388) RGD PMID:23918388 MGI:MGI:5509071 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Zfpm2 zinc finger protein, multitype 2 ISO
IEA
RNAcentral:URS000075EEC2_10090 (MGI:MGI:5770062|PMID:22267003)
GO_REF:0000107
RGD
Ensembl
PMID:22267003 GO_REF:0000107, MGI:MGI:5770062 NCBI chr 7:79,471,277...79,964,405
Ensembl chr 7:79,638,046...79,964,405
JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18194989 RGD:5129139 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP
IDA
RGD PMID:21550986, PMID:16306226 RGD:6902940, RGD:2312613 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:21376054 RGD:5129173 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:20116367 RGD:10401141 NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568
JBrowse link
G Edn1 endothelin 1 ISO RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217) RGD PMID:24117217 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:19716825 RGD:2316294 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Hamp hepcidin antimicrobial peptide IMP RGD PMID:24424338 RGD:11041632 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Igf1 insulin-like growth factor 1 ISO
IEA
RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217)
GO_REF:0000107
RGD
Ensembl
PMID:24117217 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21318349, PMID:21933187 RGD:10040977, RGD:10040978 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22989630 RGD:7174736 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 IMP RGD PMID:23261455 RGD:13514044 NCBI chr15:27,739,416...27,749,650
Ensembl chr15:27,739,251...27,749,648
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:23487407 RGD:8693424 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615
JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:25281201 RGD:13514043 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:21325829 RGD:9681466 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:9,689,214...9,702,353
Ensembl chr 9:9,689,475...9,702,306
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    multicellular organismal process 9055
      organ growth 213
        positive regulation of organ growth 59
          positive regulation of heart growth 47
            positive regulation of cardiac muscle tissue growth + 44
Path 2
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            circulatory system development 1224
              heart development 687
                heart growth 121
                  regulation of heart growth 88
                    positive regulation of heart growth 47
                      positive regulation of cardiac muscle tissue growth + 44
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.