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ONTOLOGY REPORT - ANNOTATIONS


Term:lung epithelium development
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Accession:GO:0060428 term browser browse the term
Definition:The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.
Synonyms:exact_synonym: pulmonary epithelium development


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lung epithelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:1624291
RGD:1600115
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
G Pkd1 polycystin 1, transient receptor potential channel interacting JBrowse link 10 13,914,057 13,962,008 RGD:1624291
RGD:1600115
G Rcn3 reticulocalbin 3 JBrowse link 1 101,076,971 101,086,198 RGD:1600115
RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Wnt7b Wnt family member 7B JBrowse link 7 126,423,418 126,465,724 RGD:1624291
alveolar primary septum development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stra6 stimulated by retinoic acid 6 JBrowse link 8 62,925,364 62,944,438 RGD:1624291
RGD:1600115
alveolar secondary septum development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:1624291
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
club cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
RGD:1600115
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
epithelial cell proliferation involved in lung morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1624291
RGD:1600115
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:1624291
RGD:1600115
lobar bronchus epithelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamtsl2 ADAMTS-like 2 JBrowse link 3 5,624,473 5,654,890 RGD:1624291
RGD:1600115
G Hoxa5 homeo box A5 RGD:1624291
lung ciliated cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
lung epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eya1 EYA transcriptional coactivator and phosphatase 1 JBrowse link 5 4,275,728 4,495,525 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
G Gpsm2 G-protein signaling modulator 2 JBrowse link 2 211,480,120 211,528,096 RGD:1624291
G Grhl2 grainyhead-like transcription factor 2 JBrowse link 7 76,058,623 76,197,360 RGD:1624291
RGD:1600115
G Insc INSC, spindle orientation adaptor protein JBrowse link 1 184,299,200 184,407,487 RGD:1624291
G Numa1 nuclear mitotic apparatus protein 1 JBrowse link 1 167,044,544 167,091,453 RGD:1624291
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:1624291
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha JBrowse link 14 100,311,224 100,360,879 RGD:1624291
G Sav1 salvador family WW domain containing protein 1 JBrowse link 6 92,376,470 92,398,678 RGD:1624291
RGD:1600115
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Tmem38b transmembrane protein 38B JBrowse link 5 70,639,156 70,675,055 RGD:1624291
RGD:1600115
G Yap1 yes-associated protein 1 JBrowse link 8 6,133,014 6,204,240 RGD:1624291
RGD:1600115
lung goblet cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
RGD:1600115
G Hoxa5 homeo box A5 RGD:1624291
G Spdef SAM pointed domain containing ets transcription factor JBrowse link 20 7,292,823 7,308,053 RGD:1624291
RGD:1600115
lung neuroendocrine cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
lung secretory cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
RGD:1600115
G Foxp4 forkhead box P4 JBrowse link 9 15,068,378 15,124,962 RGD:1624291
negative regulation of epithelial cell proliferation involved in lung morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
RGD:1600115
G Foxp4 forkhead box P4 JBrowse link 9 15,068,378 15,124,962 RGD:1624291
positive regulation of epithelial cell proliferation involved in lung morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:1624291
RGD:1600115
G Fgf7 fibroblast growth factor 7 JBrowse link 3 118,315,859 118,368,464 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Foxp2 forkhead box P2 JBrowse link 4 41,364,441 41,944,685 RGD:1624291
RGD:1600115
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
G Srsf6 serine and arginine rich splicing factor 6 JBrowse link 3 159,305,345 159,310,668 RGD:1624291
RGD:1600115
G Wnt2 Wnt family member 2 JBrowse link 4 45,286,845 45,332,899 RGD:1624291
RGD:1600115
positive regulation of lung ciliated cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
regulation of epithelial cell proliferation involved in lung morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
regulation of lung goblet cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Foxp4 forkhead box P4 JBrowse link 9 15,068,378 15,124,962 RGD:1624291
type I pneumocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Klf2 Kruppel-like factor 2 JBrowse link 16 19,223,087 19,225,037 RGD:1624291
RGD:1600115
G Lta4h leukotriene A4 hydrolase JBrowse link 7 34,288,333 34,320,243 RGD:2316585
G Ncor2 nuclear receptor co-repressor 2 JBrowse link 12 36,871,917 37,033,701 RGD:1624291
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:1624291
RGD:13792537
RGD:1600115
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:1624291
RGD:13792537
RGD:1600115
type II pneumocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 JBrowse link 12 12,738,784 12,748,345 RGD:1624291
RGD:1600115
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fndc3b fibronectin type III domain containing 3B JBrowse link 2 113,109,949 113,415,171 RGD:1624291
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    developmental process 6539
      anatomical structure development 6020
        tissue development 2024
          epithelium development 1195
            lung epithelium development 53
              alveolar primary septum development 1
              alveolar secondary septum development 3
              epithelial cell proliferation involved in lung morphogenesis + 12
              lobar bronchus epithelium development + 6
              lung basal cell differentiation 0
              lung epithelial cell differentiation + 34
Path 2
Term Annotations click to browse term
  biological_process 18166
    developmental process 6539
      anatomical structure development 6020
        multicellular organism development 5501
          system development 5050
            animal organ development 3862
              respiratory tube development 258
                lung development 255
                  lung epithelium development 53
                    alveolar primary septum development 1
                    alveolar secondary septum development 3
                    epithelial cell proliferation involved in lung morphogenesis + 12
                    lobar bronchus epithelium development + 6
                    lung basal cell differentiation 0
                    lung epithelial cell differentiation + 34
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.