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ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland morphogenesis
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Accession:GO:0060443 term browser browse the term
Definition:The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


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mammary gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rln1 relaxin 1 JBrowse link 1 247,483,298 247,486,331 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
G Zfp157 zinc finger protein 157 JBrowse link 12 18,461,283 18,495,871 RGD:1624291
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034833.1 RGD:13792537
G AABR07071701.1 RGD:13792537
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 1 265,100,094 265,270,263 RGD:1624291
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:1624291
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
G Ddr1 discoidin domain receptor tyrosine kinase 1 JBrowse link 20 3,553,430 3,574,959 RGD:1624291
RGD:1600115
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:1624291
G Etv4 ETS variant transcription factor 4 JBrowse link 10 89,685,058 89,700,300 RGD:1624291
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
G LOC102554748 nidogen-2-like JBrowse link 7 380,313 427,615 RGD:13792537
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:1624291
RGD:13792537
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
G Tbx3 T-box transcription factor 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
fibroblast growth factor receptor signaling pathway involved in mammary gland specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
mammary duct terminal end bud growth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:1624291
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
G Mst1 macrophage stimulating 1 JBrowse link 8 116,857,716 116,862,286 RGD:1624291
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1624291
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
mammary gland branching involved in pregnancy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
mammary gland branching involved in thelarche term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
G Ncoa3 nuclear receptor coactivator 3 JBrowse link 3 162,692,176 162,788,582 RGD:1624291
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
mammary gland bud elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
mammary gland bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
mammary gland bud morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sostdc1 sclerostin domain containing 1 JBrowse link 6 55,812,820 55,816,994 RGD:1624291
mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:1624291
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1624291
G Ntn1 netrin 1 JBrowse link 10 54,761,925 54,982,072 RGD:1624291
RGD:1600115
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
mammary gland formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
mammary gland involution term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4142798
G Bsx brain specific homeobox JBrowse link 8 45,061,670 45,065,430 RGD:1624291
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:1624291
RGD:1600115
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Elf3 E74 like ETS transcription factor 3 JBrowse link 13 52,083,873 52,088,798 RGD:1624291
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2290014
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:2290014
G Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 9 80,154,230 80,166,813 RGD:1624291
G Sfrp4 secreted frizzled-related protein 4 JBrowse link 17 47,383,983 47,394,065 RGD:4107723
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:2291942
mammary gland specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:1624291
mammary placode formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Nrg3 neuregulin 3 JBrowse link 16 15,763,031 16,932,208 RGD:1624291
G Tbx2 T-box transcription factor 2 JBrowse link 10 73,278,932 73,290,764 RGD:1624291
G Tbx3 T-box transcription factor 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
positive regulation of apoptotic process involved in mammary gland involution term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B4galt1 beta-1,4-galactosyltransferase 1 JBrowse link 5 57,121,768 57,168,610 RGD:1624291
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
G Etv5 ETS variant transcription factor 5 JBrowse link 11 82,194,657 82,252,145 RGD:1624291
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:1624291
RGD:1600115
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    developmental process 6674
      anatomical structure morphogenesis 2838
        animal organ morphogenesis 1135
          gland morphogenesis 166
            mammary gland morphogenesis 65
              mammary gland duct morphogenesis + 43
              mammary gland formation + 9
              mammary gland involution + 15
Path 2
Term Annotations click to browse term
  biological_process 19439
    developmental process 6674
      anatomical structure development 6139
        multicellular organism development 5606
          system development 5127
            animal organ development 3917
              gland development 655
                gland morphogenesis 166
                  mammary gland morphogenesis 65
                    mammary gland duct morphogenesis + 43
                    mammary gland formation + 9
                    mammary gland involution + 15
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.