ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of fertilization
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Accession:GO:0060467 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).


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negative regulation of acrosome reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spink13 serine peptidase inhibitor, Kazal type 13 (putative) JBrowse link 18 57,935,271 58,081,096 RGD:8553255
negative regulation of binding of sperm to zona pellucida term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Astl astacin like metalloendopeptidase JBrowse link 3 119,783,717 119,799,450 RGD:1624291
RGD:13792537
G Zp3 zona pellucida glycoprotein 3 JBrowse link 12 23,735,225 23,752,734 RGD:1624291
RGD:1600115
G Zp4 zona pellucida glycoprotein 4 JBrowse link 17 65,497,359 65,503,912 RGD:1600115
RGD:1624291
prevention of polyspermy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam24 ADAM metallopeptidase domain 24 JBrowse link 16 54,625,789 54,631,824 RGD:1600115
RGD:1624291
G Astl astacin like metalloendopeptidase JBrowse link 3 119,783,717 119,799,450 RGD:1624291
RGD:13792537
G Tpst2 tyrosylprotein sulfotransferase 2 JBrowse link 12 50,343,076 50,383,534 RGD:1624291
G Zp2 zona pellucida glycoprotein 2 JBrowse link 1 189,899,906 189,911,650 RGD:1600115
RGD:8554097
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    reproductive process 1660
      negative regulation of reproductive process 73
        negative regulation of fertilization 7
          negative regulation of acrosome reaction 1
          negative regulation of binding of sperm to zona pellucida 3
          negative regulation of fusion of sperm to egg plasma membrane 0
          prevention of polyspermy + 4
Path 2
Term Annotations click to browse term
  biological_process 17926
    reproduction 1663
      reproductive process 1660
        multi-organism reproductive process 1151
          sexual reproduction 903
            fertilization 178
              regulation of fertilization 30
                negative regulation of fertilization 7
                  negative regulation of acrosome reaction 1
                  negative regulation of binding of sperm to zona pellucida 3
                  negative regulation of fusion of sperm to egg plasma membrane 0
                  prevention of polyspermy + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.