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Term:negative regulation of fertilization
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Accession:GO:0060467 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).

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prevention of polyspermy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam24 a disintegrin and metallopeptidase domain 24 ISO MGI:MGI:4437125 (MGI:MGI:4429778|PMID:19670298) RGD PMID:19670298 MGI:MGI:4429778 NCBI chr16:54,625,789...54,631,824
Ensembl chr16:54,625,847...54,628,458
JBrowse link
G Astl astacin like metalloendopeptidase ISO (MGI:MGI:5427546|PMID:22472438) RGD PMID:22472438 MGI:MGI:5427546 NCBI chr 3:119,783,717...119,799,450
Ensembl chr 3:119,783,717...119,799,450
JBrowse link
G Tpst2 tyrosylprotein sulfotransferase 2 ISO MGI:MGI:3512111 (MGI:MGI:4948779|PMID:21339297) RGD PMID:21339297 MGI:MGI:4948779 NCBI chr12:50,343,076...50,383,534
Ensembl chr12:50,343,086...50,383,496
JBrowse link
G Zp2 zona pellucida glycoprotein 2 IEA
PMID:22472438, PMID:22472438 GO_REF:0000107, MGI:MGI:5427546, RGD:8554097 NCBI chr 1:189,899,906...189,911,650
Ensembl chr 1:189,899,892...189,911,650
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    reproductive process 1797
      negative regulation of reproductive process 75
        negative regulation of fertilization 4
          prevention of polyspermy + 4
Path 2
Term Annotations click to browse term
  biological_process 20027
    reproduction 1800
      reproductive process 1797
        multi-organism reproductive process 1248
          sexual reproduction 992
            fertilization 195
              regulation of fertilization 14
                negative regulation of fertilization 4
                  prevention of polyspermy + 4
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.