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ONTOLOGY REPORT - ANNOTATIONS


Term:lung cell differentiation
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Accession:GO:0060479 term browser browse the term
Definition:The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms:exact_synonym: pulmonary cell differentiation


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lung cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
Clara cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
RGD:1600115
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
lung ciliated cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
lung epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eya1 EYA transcriptional coactivator and phosphatase 1 JBrowse link 5 4,275,728 4,495,525 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
G Gpsm2 G-protein signaling modulator 2 JBrowse link 2 211,480,120 211,528,096 RGD:1624291
G Grhl2 grainyhead-like transcription factor 2 JBrowse link 7 76,058,623 76,197,360 RGD:1624291
RGD:1600115
G Insc INSC, spindle orientation adaptor protein JBrowse link 1 184,299,200 184,407,487 RGD:1624291
G Numa1 nuclear mitotic apparatus protein 1 JBrowse link 1 167,044,544 167,091,453 RGD:1624291
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:1624291
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha JBrowse link 14 100,311,224 100,360,879 RGD:1624291
G Sav1 salvador family WW domain containing protein 1 JBrowse link 6 92,376,470 92,398,678 RGD:1624291
RGD:1600115
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Tmem38b transmembrane protein 38B JBrowse link 5 70,639,156 70,675,055 RGD:1624291
RGD:1600115
G Yap1 yes-associated protein 1 JBrowse link 8 6,133,014 6,204,240 RGD:1624291
RGD:1600115
lung goblet cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
RGD:1600115
G Hoxa5 homeo box A5 RGD:1624291
G Spdef SAM pointed domain containing ets transcription factor JBrowse link 20 7,292,823 7,308,053 RGD:1624291
RGD:1600115
lung neuroendocrine cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
lung secretory cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
RGD:1600115
G Foxp4 forkhead box P4 JBrowse link 9 15,068,378 15,124,962 RGD:1624291
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
RGD:1600115
G Foxp4 forkhead box P4 JBrowse link 9 15,068,378 15,124,962 RGD:1624291
positive regulation of lung ciliated cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
regulation of lung goblet cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Foxp4 forkhead box P4 JBrowse link 9 15,068,378 15,124,962 RGD:1624291
type I pneumocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Klf2 Kruppel-like factor 2 JBrowse link 16 19,223,087 19,225,037 RGD:1624291
RGD:1600115
G Lta4h leukotriene A4 hydrolase JBrowse link 7 34,288,333 34,320,243 RGD:2316585
G Ncor2 nuclear receptor co-repressor 2 JBrowse link 12 36,871,917 37,033,701 RGD:1624291
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:1624291
RGD:13792537
RGD:1600115
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:1624291
RGD:13792537
RGD:1600115
type II pneumocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 JBrowse link 12 12,738,784 12,748,345 RGD:1624291
RGD:1600115
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fndc3b fibronectin type III domain containing 3B JBrowse link 2 113,109,949 113,415,171 RGD:1624291
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17967
    developmental process 6388
      cellular developmental process 4358
        cell differentiation 4142
          lung cell differentiation 35
            lung basal cell differentiation 0
            lung epithelial cell differentiation + 34
Path 2
Term Annotations click to browse term
  biological_process 17967
    developmental process 6388
      anatomical structure development 5991
        multicellular organism development 5486
          system development 5036
            animal organ development 3852
              respiratory tube development 257
                lung development 254
                  lung cell differentiation 35
                    lung basal cell differentiation 0
                    lung epithelial cell differentiation + 34
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.