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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of strand invasion
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Accession:GO:0060543 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
Synonyms:exact_synonym: negative regulation of Rad51-mediated strand invasion
 related_synonym: negative regulation of D-loop biosynthesis;   negative regulation of D-loop formation


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Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      cellular metabolic process 10918
        cellular macromolecule metabolic process 8393
          DNA metabolic process 911
            strand invasion 5
              negative regulation of strand invasion 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      cellular metabolic process 10918
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              DNA metabolic process 911
                DNA recombination 327
                  regulation of DNA recombination 106
                    negative regulation of DNA recombination 46
                      negative regulation of strand invasion 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.