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ONTOLOGY REPORT - ANNOTATIONS


Term:ventral spinal cord interneuron fate determination
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Accession:GO:0060580 term browser browse the term
Definition:The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.


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ventral spinal cord interneuron fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 ISO MGI:MGI:1932100 (MGI:MGI:1334824|PMID:10217145) RGD PMID:10217145 MGI:MGI:1334824 NCBI chr 3:141,408,460...141,419,083
Ensembl chr 3:141,408,798...141,411,170
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  biological_process 20028
    multicellular organismal process 9046
      pattern specification process 496
        cell fate commitment involved in pattern specification 16
          ventral spinal cord interneuron fate commitment 16
            ventral spinal cord interneuron fate determination 1
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  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            nervous system development 2722
              neurogenesis 1938
                generation of neurons 1781
                  neuron differentiation 1617
                    central nervous system neuron differentiation 243
                      ventral spinal cord interneuron differentiation 18
                        ventral spinal cord interneuron fate commitment 16
                          ventral spinal cord interneuron fate determination 1
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