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ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland duct morphogenesis
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Accession:GO:0060603 term browser browse the term
Definition:The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.


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mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 ISO (MGI:2151643|PMID:11783999) MGI PMID:11783999 MGI:2151643 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442
JBrowse link
G LRP5 LDL receptor related protein 5 ISO (MGI:3849913|PMID:19503830) MGI PMID:19503830 MGI:3849913 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817
JBrowse link
G LRP6 LDL receptor related protein 6 ISO (MGI:3849913|PMID:19503830) MGI PMID:19503830 MGI:3849913 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO (MGI:3758540|PMID:12198239) MGI PMID:12198239 MGI:3758540 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269
JBrowse link
G NTN1 netrin 1 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr17:42,409,797...42,631,930
Ensembl chr17:47,152,225...47,368,134
JBrowse link
G PTCH1 patched 1 ISO (MGI:1346456|PMID:10529434) MGI PMID:10529434 MGI:1346456 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453
JBrowse link
G SCRIB scribble planar cell polarity protein ISO (MGI:4359580|PMID:19041750) UniProt PMID:19041750 MGI:4359580 NCBI chr 8:140,544,797...140,571,078
Ensembl chr 8:143,557,722...143,582,353
JBrowse link
G SLIT2 slit guidance ligand 2 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656
JBrowse link
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB1 transforming growth factor beta 1 ISO (MGI:3814777|PMID:18614704) MGI PMID:18614704 MGI:3814777 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase ISO (MGI:3054694|PMID:15340078) MGI PMID:15340078 MGI:3054694 NCBI chr10:97,958,527...98,159,550
Ensembl chr10:101,431,318...101,632,496
JBrowse link
G CSF1 colony stimulating factor 1 ISO (MGI:3640884|PMID:10804170) MGI PMID:10804170 MGI:3640884 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943
JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 ISO (MGI:1932625|PMID:11283268) MGI PMID:11283268 MGI:1932625 NCBI chr 6:30,625,871...30,645,066
Ensembl chr 6:31,496,047...31,513,455
JBrowse link
G EPHA2 EPH receptor A2 ISO (MGI:5284750|PMID:19321667) UniProt PMID:19321667 MGI:5284750 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787
JBrowse link
G ETV4 ETS variant transcription factor 4 ISO (MGI:3828920|PMID:18977342)
(MGI:2667785|PMID:12871699)
MGI PMID:12871699, PMID:18977342 MGI:2667785, MGI:3828920 NCBI chr17:13,850,823...13,869,347
Ensembl chr17:14,099,160...14,116,186
JBrowse link
G KDM5B lysine demethylase 5B ISO (MGI:5619178|PMID:24802759) MGI PMID:24802759 MGI:5619178 NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994
JBrowse link
G LRP5 LDL receptor related protein 5 ISO (MGI:3692480|PMID:16973609) MGI PMID:16973609 MGI:3692480 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817
JBrowse link
G LRP6 LDL receptor related protein 6 ISO (MGI:3849913|PMID:19503830) MGI PMID:19503830 MGI:3849913 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G MSX2 msh homeobox 2 ISO (MGI:1355063|PMID:10742104) MGI PMID:10742104 MGI:1355063 NCBI chr 5:170,063,137...170,070,226
Ensembl chr 5:176,967,902...176,976,609
JBrowse link
G PML PML nuclear body scaffold ISO (MGI:3839212|PMID:19261859) MGI PMID:19261859 MGI:3839212 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO (MGI:2180693|PMID:8864124) MGI PMID:8864124 MGI:2180693 NCBI chr 5:123,499,267...123,603,777
Ensembl chr 5:129,262,134...129,364,563
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO (MGI:3589531|PMID:16007215) MGI PMID:16007215 MGI:3589531 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G TBX3 T-box transcription factor 3 ISO (MGI:3608166|PMID:16222716) MGI PMID:16222716 MGI:3608166 NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316
JBrowse link
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin ISO (MGI:3703920|PMID:17369357) MGI PMID:17369357 MGI:3703920 NCBI chr 4:49,737,191...49,747,013 JBrowse link
G TFAP2C transcription factor AP-2 gamma ISO (MGI:4422106|PMID:20131354) MGI PMID:20131354 MGI:4422106 NCBI chr20:52,966,907...52,981,024
Ensembl chr20:54,255,489...54,265,432
JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin ISO (MGI:3703920|PMID:17369357) MGI PMID:17369357 MGI:3703920 NCBI chr 4:49,737,191...49,747,013 JBrowse link
G ESR1 estrogen receptor 1 ISO (MGI:3629536|PMID:12021201) MGI PMID:12021201 MGI:3629536 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G MED1 mediator complex subunit 1 ISO (MGI:3576991|PMID:15647257) MGI PMID:15647257 MGI:3576991 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G TFAP2C transcription factor AP-2 gamma ISO (MGI:4422106|PMID:20131354) MGI PMID:20131354 MGI:4422106 NCBI chr20:52,966,907...52,981,024
Ensembl chr20:54,255,489...54,265,432
JBrowse link
G WNT5A Wnt family member 5A ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor ISO (MGI:2683859|PMID:14676301) MGI PMID:14676301 MGI:2683859 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357
JBrowse link
G WNT5A Wnt family member 5A ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
mammary duct terminal end bud growth term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF1 colony stimulating factor 1 ISO (MGI:3640884|PMID:10804170) MGI PMID:10804170 MGI:3640884 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943
JBrowse link
G KDM5B lysine demethylase 5B ISO (MGI:5619178|PMID:24802759) MGI PMID:24802759 MGI:5619178 NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994
JBrowse link
G MST1 macrophage stimulating 1 ISO (MGI:5614192|PMID:25049204) MGI PMID:25049204 MGI:5614192 NCBI chr 3:49,616,339...49,621,749 JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308
JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO (MGI:2180453|PMID:12040017) MGI PMID:12040017 MGI:2180453 NCBI chr 5:123,499,267...123,603,777
Ensembl chr 5:129,262,134...129,364,563
JBrowse link
G SLIT2 slit guidance ligand 2 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656
JBrowse link
mammary gland branching involved in pregnancy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSMD1 CUB and Sushi multiple domains 1 ISO (MGI:6369467|PMID:31604923) MGI PMID:31604923 MGI:6369467 NCBI chr 8:2,282,763...4,351,724
Ensembl chr 8:2,838,803...4,923,373
JBrowse link
G ESR1 estrogen receptor 1 ISO (MGI:1926565|PMID:10919287) MGI PMID:10919287 MGI:1926565 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G MED1 mediator complex subunit 1 ISO (MGI:3576991|PMID:15647257) MGI PMID:15647257 MGI:3576991 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G VDR vitamin D receptor ISO (MGI:3051725|PMID:15178742) MGI PMID:15178742 MGI:3051725 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin ISO (MGI:1336843|PMID:10331984), (MGI:3703920|PMID:17369357) MGI PMID:10331984, PMID:17369357 MGI:1336843, MGI:3703920 NCBI chr 4:49,737,191...49,747,013 JBrowse link
G MED1 mediator complex subunit 1 ISO (MGI:3576991|PMID:15647257) MGI PMID:15647257 MGI:3576991 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G NCOA3 nuclear receptor coactivator 3 ISO (MGI:1859522|PMID:11015591) MGI PMID:11015591 MGI:1859522 NCBI chr20:43,838,227...43,992,407
Ensembl chr20:45,000,422...45,073,549
JBrowse link
G PHB2 prohibitin 2 ISO (MGI:3695669|PMID:17065319) MGI PMID:17065319 MGI:3695669 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO (MGI:3814777|PMID:18614704) MGI PMID:18614704 MGI:3814777 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G WNT5A Wnt family member 5A ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
mammary gland bud elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTHLH parathyroid hormone like hormone ISO (MGI:1203302|PMID:9477327) MGI PMID:9477327 MGI:1203302 NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750
JBrowse link
mammary gland bud formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF10 fibroblast growth factor 10 ISO (MGI:2155478|PMID:11782400) MGI PMID:11782400 MGI:2155478 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO (MGI:2155478|PMID:11782400) MGI PMID:11782400 MGI:2155478 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815
JBrowse link
mammary gland bud morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOSTDC1 sclerostin domain containing 1 ISO (MGI:5319554|PMID:22509524) MGI PMID:22509524 MGI:5319554 NCBI chr 7:17,116,828...17,121,142
Ensembl chr 7:16,443,703...16,448,076
JBrowse link
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV3 caveolin 3 ISO (MGI:3830397|PMID:19164602) MGI PMID:19164602 MGI:3830397 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G ETV5 ETS variant transcription factor 5 ISO (MGI:2667785|PMID:12871699) MGI PMID:12871699 MGI:2667785 NCBI chr 3:183,076,677...183,139,886
Ensembl chr 3:191,545,915...191,606,550
JBrowse link
G PHB2 prohibitin 2 ISO (MGI:3695669|PMID:17065319) MGI PMID:17065319 MGI:3695669 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G WNT5A Wnt family member 5A ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor ISO (MGI:2683859|PMID:14676301) MGI PMID:14676301 MGI:2683859 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357
JBrowse link
G PGR progesterone receptor ISO (MGI:1354852|PMID:10733525) MGI PMID:10733525 MGI:1354852 NCBI chr11:95,997,677...96,098,866 JBrowse link
G WNT4 Wnt family member 4 ISO (MGI:1354852|PMID:10733525) MGI PMID:10733525 MGI:1354852 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    developmental process 5839
      anatomical structure morphogenesis 2581
        tube morphogenesis 873
          epithelial tube morphogenesis 386
            mammary gland duct morphogenesis 40
              branching involved in mammary gland duct morphogenesis + 28
              mammary duct terminal end bud growth 6
              mammary gland bud morphogenesis + 4
              mammary gland cord morphogenesis + 0
              mammary gland duct cavitation 0
              mammary gland duct regression in males 0
Path 2
Term Annotations click to browse term
  biological_process 12566
    developmental process 5839
      anatomical structure development 5452
        multicellular organism development 4984
          system development 4688
            animal organ development 3618
              animal organ morphogenesis 1040
                gland morphogenesis 161
                  mammary gland morphogenesis 62
                    mammary gland duct morphogenesis 40
                      branching involved in mammary gland duct morphogenesis + 28
                      mammary duct terminal end bud growth 6
                      mammary gland bud morphogenesis + 4
                      mammary gland cord morphogenesis + 0
                      mammary gland duct cavitation 0
                      mammary gland duct regression in males 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.