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ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland duct morphogenesis
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Accession:GO:0060603 term browser browse the term
Definition:The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.


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mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 IEA Ensembl GO_REF:0000107 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658
JBrowse link
G LRP5 LDL receptor related protein 5 ISO (MGI:3849913|PMID:19503830) MGI PMID:19503830 MGI:3849913 NCBI chr18:49,439,494...49,555,375
Ensembl chr18:49,439,483...49,516,396
JBrowse link
G LRP6 LDL receptor related protein 6 ISO (MGI:3849913|PMID:19503830) MGI PMID:19503830 MGI:3849913 NCBI chr27:34,003,334...34,166,334
Ensembl chr27:34,003,539...34,161,437
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO (MGI:3758540|PMID:12198239) MGI PMID:12198239 MGI:3758540 NCBI chr 2:38,124,568...38,242,510
Ensembl chr 2:38,123,190...38,240,755
JBrowse link
G NTN1 netrin 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:33,654,723...33,825,832
Ensembl chr 5:33,637,142...33,825,899
JBrowse link
G PTCH1 patched 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662
JBrowse link
G SCRIB scribble planar cell polarity protein IEA Ensembl GO_REF:0000107 NCBI chr13:37,356,405...37,374,765
Ensembl chr13:37,356,405...37,374,681
JBrowse link
G SLIT2 slit guidance ligand 2 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 ISO (MGI:3814777|PMID:18614704) MGI PMID:18614704 MGI:3814777 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G TGFB1 transforming growth factor beta 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr28:13,988,408...14,173,223
Ensembl chr28:13,988,432...14,169,581
JBrowse link
G CSF1 colony stimulating factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371
JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr12:653,800...671,190
Ensembl chr12:653,807...670,543
JBrowse link
G EPHA2 EPH receptor A2 IEA Ensembl GO_REF:0000107 NCBI chr 2:81,534,130...81,561,722
Ensembl chr 2:81,534,125...81,561,725
JBrowse link
G ETV4 ETS variant transcription factor 4 ISO (MGI:2667785|PMID:12871699)
(MGI:3828920|PMID:18977342)
MGI PMID:12871699, PMID:18977342 MGI:2667785, MGI:3828920 NCBI chr 9:19,715,259...19,731,085
Ensembl chr 9:19,715,535...19,730,456
JBrowse link
G KDM5B lysine demethylase 5B IEA Ensembl GO_REF:0000107 NCBI chr 7:336,452...415,568
Ensembl chr 7:330,705...412,386
JBrowse link
G LRP5 LDL receptor related protein 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:49,439,494...49,555,375
Ensembl chr18:49,439,483...49,516,396
JBrowse link
G LRP6 LDL receptor related protein 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr27:34,003,334...34,166,334
Ensembl chr27:34,003,539...34,161,437
JBrowse link
G MSX2 msh homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407
JBrowse link
G PML PML nuclear body scaffold IEA Ensembl GO_REF:0000107 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741
JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO (MGI:2180693|PMID:8864124) MGI PMID:8864124 MGI:2180693 NCBI chr11:17,143,943...17,256,248
Ensembl chr11:17,143,943...17,253,695
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
G TBX3 T-box transcription factor 3 IEA Ensembl GO_REF:0000107 NCBI chr26:11,694,885...11,709,594
Ensembl chr26:11,696,565...11,708,918
JBrowse link
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin IEA Ensembl GO_REF:0000107 NCBI chr13:62,925,761...62,936,753
Ensembl chr13:62,926,301...62,936,738
JBrowse link
G TFAP2C transcription factor AP-2 gamma ISO (MGI:4422106|PMID:20131354) MGI PMID:20131354 MGI:4422106 NCBI chr24:41,787,477...41,797,446
Ensembl chr24:41,783,490...41,796,509
JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin IEA Ensembl GO_REF:0000107 NCBI chr13:62,925,761...62,936,753
Ensembl chr13:62,926,301...62,936,738
JBrowse link
G ESR1 estrogen receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544
JBrowse link
G MED1 mediator complex subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349
JBrowse link
G TFAP2C transcription factor AP-2 gamma ISO (MGI:4422106|PMID:20131354) MGI PMID:20131354 MGI:4422106 NCBI chr24:41,787,477...41,797,446
Ensembl chr24:41,783,490...41,796,509
JBrowse link
G WNT5A Wnt family member 5A IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor IEA Ensembl GO_REF:0000107 NCBI chr24:34,713,390...34,731,461
NCBI chr  X:51,969,785...52,167,450
Ensembl chr  X:51,969,785...52,151,912
JBrowse link
G WNT5A Wnt family member 5A IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
mammary duct terminal end bud growth term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF1 colony stimulating factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371
JBrowse link
G KDM5B lysine demethylase 5B IEA Ensembl GO_REF:0000107 NCBI chr 7:336,452...415,568
Ensembl chr 7:330,705...412,386
JBrowse link
G MST1 macrophage stimulating 1 IEA Ensembl GO_REF:0000107 NCBI chr20:39,582,237...39,586,958
Ensembl chr20:39,582,282...39,586,908
JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr31:8,082,363...8,594,623
Ensembl chr31:7,626,126...8,593,728
JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO (MGI:2180453|PMID:12040017) MGI PMID:12040017 MGI:2180453 NCBI chr11:17,143,943...17,256,248
Ensembl chr11:17,143,943...17,253,695
JBrowse link
G SLIT2 slit guidance ligand 2 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
mammary gland branching involved in pregnancy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSMD1 CUB and Sushi multiple domains 1 ISO (MGI:6369467|PMID:31604923) MGI PMID:31604923 MGI:6369467 NCBI chr16:55,142,990...56,673,978
Ensembl chr16:55,143,199...56,673,679
JBrowse link
G ESR1 estrogen receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544
JBrowse link
G MED1 mediator complex subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349
JBrowse link
G VDR vitamin D receptor IEA Ensembl GO_REF:0000107 NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470
JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin IEA Ensembl GO_REF:0000107 NCBI chr13:62,925,761...62,936,753
Ensembl chr13:62,926,301...62,936,738
JBrowse link
G B9D2 B9 domain containing 2 ISO (MGI:3814777|PMID:18614704) MGI PMID:18614704 MGI:3814777 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G MED1 mediator complex subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349
JBrowse link
G PHB2 prohibitin 2 IEA Ensembl GO_REF:0000107 NCBI chr27:38,075,769...38,080,440
Ensembl chr27:38,075,652...38,080,109
JBrowse link
G TGFB1 transforming growth factor beta 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G WNT5A Wnt family member 5A IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
mammary gland bud elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTHLH parathyroid hormone like hormone ISO (MGI:1203302|PMID:9477327) MGI PMID:9477327 MGI:1203302 NCBI chr27:19,781,557...19,795,078
Ensembl chr27:19,781,557...19,795,078
JBrowse link
mammary gland bud formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF10 fibroblast growth factor 10 IEA Ensembl GO_REF:0000107 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO (MGI:2155478|PMID:11782400) MGI PMID:11782400 MGI:2155478 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621
JBrowse link
mammary gland bud morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOSTDC1 sclerostin domain containing 1 IEA Ensembl GO_REF:0000107 NCBI chr14:31,022,599...31,027,155
Ensembl chr14:31,022,766...31,026,737
JBrowse link
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G CAV3 caveolin 3 IEA Ensembl GO_REF:0000107 NCBI chr20:9,384,901...9,398,055
Ensembl chr20:9,384,901...9,401,196
JBrowse link
G ETV5 ETS variant transcription factor 5 ISO (MGI:2667785|PMID:12871699) MGI PMID:12871699 MGI:2667785 NCBI chr34:18,729,684...18,791,667
Ensembl chr34:18,731,943...18,789,386
JBrowse link
G PHB2 prohibitin 2 IEA Ensembl GO_REF:0000107 NCBI chr27:38,075,769...38,080,440
Ensembl chr27:38,075,652...38,080,109
JBrowse link
G TGFB1 transforming growth factor beta 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G WNT5A Wnt family member 5A IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor IEA Ensembl GO_REF:0000107 NCBI chr24:34,713,390...34,731,461
NCBI chr  X:51,969,785...52,167,450
Ensembl chr  X:51,969,785...52,151,912
JBrowse link
G PGR progesterone receptor IEA Ensembl GO_REF:0000107 NCBI chr21:447,197...552,511
Ensembl chr21:447,319...552,511
JBrowse link
G WNT4 Wnt family member 4 IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16186
    developmental process 6313
      anatomical structure morphogenesis 2786
        tube morphogenesis 897
          epithelial tube morphogenesis 383
            mammary gland duct morphogenesis 40
              branching involved in mammary gland duct morphogenesis + 28
              mammary duct terminal end bud growth 6
              mammary gland bud morphogenesis + 4
              mammary gland cord morphogenesis + 0
              mammary gland duct cavitation 0
              mammary gland duct regression in males 0
Path 2
Term Annotations click to browse term
  biological_process 16186
    developmental process 6313
      anatomical structure development 5861
        multicellular organism development 5354
          system development 4986
            animal organ development 3823
              animal organ morphogenesis 1114
                gland morphogenesis 162
                  mammary gland morphogenesis 62
                    mammary gland duct morphogenesis 40
                      branching involved in mammary gland duct morphogenesis + 28
                      mammary duct terminal end bud growth 6
                      mammary gland bud morphogenesis + 4
                      mammary gland cord morphogenesis + 0
                      mammary gland duct cavitation 0
                      mammary gland duct regression in males 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.