Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:tube closure
go back to main search page
Accession:GO:0060606 term browser browse the term
Definition:Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.


show annotations for term's descendants       view all columns           Sort by:
 
tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
anterior neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
G Grhl2 grainyhead-like transcription factor 2 JBrowse link 7 76,058,623 76,197,360 RGD:1624291
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like JBrowse link 20 14,287,470 14,393,879 RGD:1624291
anterior neuropore closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gatad2a GATA zinc finger domain containing 2A JBrowse link 16 21,177,793 21,267,768 RGD:1624291
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
establishment of planar polarity involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cthrc1 collagen triple helix repeat containing 1 JBrowse link 7 77,966,722 77,977,004 RGD:1624291
G Vangl2 VANGL planar cell polarity protein 2 JBrowse link 13 90,379,203 90,405,627 RGD:1624291
initiation of neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm2b lysine demethylase 2B JBrowse link 12 39,021,924 39,161,954 RGD:1624291
negative regulation of planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 13 74,154,533 74,333,244 RGD:1624291
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1624291
G Alx1 ALX homeobox 1 JBrowse link 7 44,751,865 44,771,458 RGD:1624291
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:1624291
G Arhgap35 Rho GTPase activating protein 35 JBrowse link 1 78,456,409 78,573,374 RGD:1624291
RGD:1600115
G Arid1a AT-rich interaction domain 1A JBrowse link 5 151,904,687 151,977,973 RGD:1624291
G Bbs4 Bardet-Biedl syndrome 4 JBrowse link 8 64,115,005 64,154,432 RGD:1624291
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
RGD:734638
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Brd2 bromodomain containing 2 JBrowse link 20 3,910,555 3,921,074 RGD:1600115
G Cc2d2a coiled-coil and C2 domain containing 2A JBrowse link 14 71,895,128 71,979,452 RGD:1624291
G Cecr2 CECR2, histone acetyl-lysine reader JBrowse link 4 153,217,521 153,327,153 RGD:1624291
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 JBrowse link 7 126,774,010 126,914,085 RGD:1624291
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 1 12,823,363 12,825,806 RGD:1624291
G Cluap1 clusterin associated protein 1 JBrowse link 10 11,847,058 11,878,792 RGD:1624291
G Cobl cordon-bleu WH2 repeat protein JBrowse link 14 92,341,949 92,497,169 RGD:1624291
RGD:1600115
G Deaf1 DEAF1 transcription factor JBrowse link 1 214,283,787 214,317,466 RGD:1600115
RGD:1624291
G Dlc1 DLC1 Rho GTPase activating protein JBrowse link 16 58,776,489 59,247,752 RGD:1624291
G Dvl2 dishevelled segment polarity protein 2 JBrowse link 10 56,609,810 56,619,269 RGD:1624291
G Enah ENAH, actin regulator JBrowse link 13 100,297,421 100,415,335 RGD:1624291
G Fuz fuzzy planar cell polarity protein JBrowse link 1 100,891,832 100,896,811 RGD:1624291
RGD:1600115
G Fzd3 frizzled class receptor 3 JBrowse link 15 48,601,259 48,670,257 RGD:1624291
G Fzd6 frizzled class receptor 6 JBrowse link 7 77,898,329 77,931,034 RGD:1624291
G Glmn glomulin, FKBP associated protein JBrowse link 14 3,204,390 3,247,703 RGD:1624291
G Grhl2 grainyhead-like transcription factor 2 JBrowse link 7 76,058,623 76,197,360 RGD:1624291
G Grhl3 grainyhead-like transcription factor 3 JBrowse link 5 153,893,039 153,925,045 RGD:1624291
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 JBrowse link 6 72,509,658 72,596,285 RGD:1624291
G Ift122 intraflagellar transport 122 JBrowse link 4 147,756,574 147,826,983 RGD:1624291
G Ift172 intraflagellar transport 172 JBrowse link 6 26,390,686 26,485,459 RGD:1624291
G Ift57 intraflagellar transport 57 JBrowse link 11 53,664,638 53,731,779 RGD:1624291
G Kat2a lysine acetyltransferase 2A JBrowse link 10 88,611,586 88,619,558 RGD:1624291
G Kdm2a lysine demethylase 2A JBrowse link 1 219,566,130 219,642,294 RGD:1624291
G Kdm6a lysine demethylase 6A JBrowse link X 4,805,493 4,945,788 RGD:1624291
G Kif20b kinesin family member 20B JBrowse link 1 253,220,038 253,275,523 RGD:1624291
G Lhx2 LIM homeobox 2 JBrowse link 3 22,628,674 22,658,447 RGD:1624291
RGD:1600115
G Lias lipoic acid synthetase JBrowse link 14 44,507,217 44,524,287 RGD:1624291
G Lmo4 LIM domain only 4 JBrowse link 2 250,218,635 250,235,435 RGD:1624291
G LOC100909544 bromodomain-containing protein 2-like JBrowse link 20 3,910,555 3,918,348 RGD:1624291
G LOC108348112 bromodomain-containing protein 2 JBrowse link 20 5,262,742 5,269,337 RGD:1600115
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:1600115
RGD:1624291
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Med12 mediator complex subunit 12 JBrowse link X 71,174,653 71,197,812 RGD:1624291
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1600115
RGD:1624291
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 JBrowse link 6 99,282,850 99,350,367 RGD:1624291
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like JBrowse link 1 40,529,092 40,719,232 RGD:1624291
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:1624291
G Nckap1 NCK-associated protein 1 JBrowse link 3 67,725,180 67,804,680 RGD:1624291
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:1624291
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:1624291
G Pfn1 profilin 1 JBrowse link 10 57,273,003 57,275,708 RGD:1624291
G Phactr4 phosphatase and actin regulator 4 JBrowse link 5 150,533,895 150,609,423 RGD:1624291
G Plxnb2 plexin B2 JBrowse link 7 130,135,484 130,161,568 RGD:1624291
G Prickle1 prickle planar cell polarity protein 1 JBrowse link 7 134,702,964 134,799,437 RGD:1600115
RGD:1624291
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1624291
RGD:1600115
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:1624291
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
G Ptk7 protein tyrosine kinase 7 JBrowse link 9 16,662,588 16,729,888 RGD:1624291
G Rab23 RAB23, member RAS oncogene family JBrowse link 9 38,469,784 38,496,185 RGD:1624291
G Rala RAS like proto-oncogene A JBrowse link 17 49,676,073 49,729,133 RGD:1624291
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:1624291
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:1624291
G Rgma repulsive guidance molecule BMP co-receptor a JBrowse link 1 134,699,053 134,742,512 RGD:1624291
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1624291
G Rps7 ribosomal protein S7 JBrowse link 6 47,899,525 47,904,389 RGD:1624291
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
G Sall4 spalt-like transcription factor 4 JBrowse link 3 165,520,155 165,538,176 RGD:1624291
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:1624291
G Sdc4 syndecan 4 JBrowse link 3 160,872,503 160,891,190 RGD:1624291
G Sec24b SEC24 homolog B, COPII coat complex component JBrowse link 2 230,286,886 230,356,887 RGD:1624291
G Sema4c semaphorin 4C JBrowse link 9 43,129,413 43,140,442 RGD:1624291
G Setd2 SET domain containing 2, histone lysine methyltransferase JBrowse link 8 118,802,478 118,888,224 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
G Shroom3 shroom family member 3 JBrowse link 14 16,622,767 16,903,265 RGD:1624291
G Ski SKI proto-oncogene JBrowse link 5 172,556,196 172,623,878 RGD:1624291
G Spint1 serine peptidase inhibitor, Kunitz type 1 JBrowse link 3 111,049,132 111,061,991 RGD:1624291
G Spint2 serine peptidase inhibitor, Kunitz type, 2 JBrowse link 1 87,199,373 87,221,826 RGD:1624291
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:1624291
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
G Tbxt T-box transcription factor T JBrowse link 1 52,887,067 52,900,691 RGD:1624291
G Tead2 TEA domain transcription factor 2 JBrowse link 1 101,213,782 101,230,483 RGD:1624291
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
G Tgif1 TGFB-induced factor homeobox 1 JBrowse link 9 119,181,079 119,190,698 RGD:1624291
G Tmed2 transmembrane p24 trafficking protein 2 JBrowse link 12 37,471,259 37,480,344 RGD:1624291
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
G Trim71 tripartite motif containing 71 JBrowse link 8 122,553,015 122,604,787 RGD:1624291
G Tsc1 TSC complex subunit 1 JBrowse link 3 7,219,955 7,269,063 RGD:1624291
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:1624291
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
G Vangl2 VANGL planar cell polarity protein 2 JBrowse link 13 90,379,203 90,405,627 RGD:1624291
G Vasp vasodilator-stimulated phosphoprotein JBrowse link 1 80,170,608 80,185,882 RGD:1624291
RGD:13792537
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
G Zeb2 zinc finger E-box binding homeobox 2 JBrowse link 3 29,857,289 29,985,932 RGD:1624291
G Zic2 Zic family member 2 JBrowse link 15 108,908,366 108,913,812 RGD:1624291
G Zic5 Zic family member 5 JBrowse link 15 108,891,992 108,907,601 RGD:1624291
planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 JBrowse link 7 126,774,010 126,914,085 RGD:1624291
G Dvl1 dishevelled segment polarity protein 1 JBrowse link 5 173,295,948 173,308,014 RGD:1624291
RGD:13792537
G Dvl2 dishevelled segment polarity protein 2 JBrowse link 10 56,609,810 56,619,269 RGD:1624291
RGD:13792537
G Dvl3 dishevelled segment polarity protein 3 JBrowse link 11 84,051,177 84,068,479 RGD:1624291
RGD:13792537
G Fzd1 frizzled class receptor 1 JBrowse link 4 26,470,864 26,475,262 RGD:1624291
RGD:1600115
G Fzd2 frizzled class receptor 2 JBrowse link 10 90,550,147 90,552,057 RGD:1624291
RGD:1600115
G Grhl3 grainyhead-like transcription factor 3 JBrowse link 5 153,893,039 153,925,045 RGD:1624291
G Ptk7 protein tyrosine kinase 7 JBrowse link 9 16,662,588 16,729,888 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1624291
RGD:1600115
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
G Sfrp5 secreted frizzled-related protein 5 JBrowse link 1 261,442,108 261,446,570 RGD:1624291
G Vangl2 VANGL planar cell polarity protein 2 JBrowse link 13 90,379,203 90,405,627 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
regulation of establishment of planar polarity involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sec24b SEC24 homolog B, COPII coat complex component JBrowse link 2 230,286,886 230,356,887 RGD:1624291
semicircular canal fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    developmental process 6697
      anatomical structure formation involved in morphogenesis 1204
        tube formation 181
          tube closure 114
            anterior neural tube closure 4
            cell-cell adhesion involved in sealing an epithelial fold + 0
            closure of embryonic heart tube 0
            neural tube closure + 113
            semicircular canal fusion + 1
Path 2
Term Annotations click to browse term
  biological_process 19578
    developmental process 6697
      anatomical structure development 6155
        multicellular organism development 5623
          tube development 1191
            tube morphogenesis 920
              tube formation 181
                tube closure 114
                  anterior neural tube closure 4
                  cell-cell adhesion involved in sealing an epithelial fold + 0
                  closure of embryonic heart tube 0
                  neural tube closure + 113
                  semicircular canal fusion + 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.