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ONTOLOGY REPORT - ANNOTATIONS


Term:inactivation of X chromosome by heterochromatin assembly
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Accession:GO:0060820 term browser browse the term
Definition:Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.
Synonyms:exact_synonym: inactivation of X chromosome by heterochromatin formation


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inactivation of X chromosome by heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 ISO (MGI:MGI:5532809|PMID:23754746) UniProtKB PMID:23754746 MGI:MGI:5532809 NCBI chr 7:69,359,286...69,505,067
Ensembl chr 7:69,358,447...69,621,067
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  biological_process 16162
    cellular process 15439
      cellular component organization or biogenesis 6022
        cellular component organization 5853
          chromatin organization 714
            chromatin remodeling 165
              heterochromatin assembly 47
                inactivation of X chromosome by heterochromatin assembly 1
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Term Annotations click to browse term
  biological_process 16162
    metabolic process 10639
      cellular metabolic process 9632
        cellular aromatic compound metabolic process 5109
          nucleobase-containing compound metabolic process 4907
            nucleic acid metabolic process 4459
              RNA metabolic process 4001
                regulation of RNA metabolic process 3278
                  negative regulation of RNA metabolic process 1385
                    negative regulation of RNA biosynthetic process 1285
                      negative regulation of nucleic acid-templated transcription 1284
                        negative regulation of transcription, DNA-templated 1257
                          chromatin organization involved in negative regulation of transcription 107
                            heterochromatin assembly 47
                              inactivation of X chromosome by heterochromatin assembly 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.