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ONTOLOGY REPORT - ANNOTATIONS


Term:inactivation of X chromosome by heterochromatin assembly
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Accession:GO:0060820 term browser browse the term
Definition:Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.
Synonyms:exact_synonym: inactivation of X chromosome by heterochromatin formation


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inactivation of X chromosome by heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 ISS UniProtKB GO_REF:0000024 NCBI chr18:2,655,726...2,805,017
Ensembl chr18:2,655,738...2,805,017
Ensembl chr18:2,655,738...2,805,017
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  biological_process 18651
    cellular process 17669
      cellular component organization or biogenesis 7122
        cellular component organization 6931
          chromatin organization 879
            chromatin remodeling 235
              heterochromatin assembly 78
                inactivation of X chromosome by heterochromatin assembly 1
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Term Annotations click to browse term
  biological_process 18651
    metabolic process 12286
      cellular metabolic process 11268
        cellular aromatic compound metabolic process 6226
          nucleobase-containing compound metabolic process 5975
            nucleic acid metabolic process 5426
              RNA metabolic process 4898
                regulation of RNA metabolic process 3998
                  negative regulation of RNA metabolic process 1598
                    negative regulation of RNA biosynthetic process 1489
                      negative regulation of nucleic acid-templated transcription 1487
                        negative regulation of transcription, DNA-templated 1445
                          chromatin organization involved in negative regulation of transcription 154
                            heterochromatin assembly 78
                              inactivation of X chromosome by heterochromatin assembly 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.