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ONTOLOGY REPORT - ANNOTATIONS


Term:inactivation of X chromosome by heterochromatin assembly
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Accession:GO:0060820 term browser browse the term
Definition:Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.
Synonyms:exact_synonym: inactivation of X chromosome by heterochromatin formation


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inactivation of X chromosome by heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:103,809,732...103,986,057
Ensembl chr 6:103,808,066...103,986,144
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  biological_process 16525
    cellular process 15757
      cellular component organization or biogenesis 5964
        cellular component organization 5795
          chromatin organization 699
            chromatin remodeling 166
              heterochromatin assembly 49
                inactivation of X chromosome by heterochromatin assembly 1
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Term Annotations click to browse term
  biological_process 16525
    metabolic process 10566
      cellular metabolic process 9561
        cellular aromatic compound metabolic process 5101
          nucleobase-containing compound metabolic process 4902
            nucleic acid metabolic process 4482
              RNA metabolic process 4015
                regulation of RNA metabolic process 3311
                  negative regulation of RNA metabolic process 1387
                    negative regulation of RNA biosynthetic process 1288
                      negative regulation of nucleic acid-templated transcription 1286
                        negative regulation of transcription, DNA-templated 1262
                          chromatin organization involved in negative regulation of transcription 101
                            heterochromatin assembly 49
                              inactivation of X chromosome by heterochromatin assembly 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.