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ONTOLOGY REPORT - ANNOTATIONS


Term:inactivation of X chromosome by heterochromatin assembly
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Accession:GO:0060820 term browser browse the term
Definition:Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.
Synonyms:exact_synonym: inactivation of X chromosome by heterochromatin formation


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inactivation of X chromosome by heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 ISO (MGI:MGI:5532809|PMID:23754746) UniProtKB PMID:23754746 MGI:MGI:5532809 NCBI chrNW_004936672:1,686,070...1,838,315 JBrowse link

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  biological_process 11968
    cellular process 11136
      cellular component organization or biogenesis 4888
        cellular component organization 4810
          chromatin organization 543
            chromatin remodeling 117
              heterochromatin assembly 41
                inactivation of X chromosome by heterochromatin assembly 1
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Term Annotations click to browse term
  biological_process 11968
    metabolic process 7653
      cellular metabolic process 7051
        cellular aromatic compound metabolic process 3743
          nucleobase-containing compound metabolic process 3574
            nucleic acid metabolic process 3288
              RNA metabolic process 2915
                regulation of RNA metabolic process 2500
                  negative regulation of RNA metabolic process 1159
                    negative regulation of RNA biosynthetic process 1068
                      negative regulation of nucleic acid-templated transcription 1066
                        negative regulation of transcription, DNA-templated 1062
                          chromatin organization involved in negative regulation of transcription 59
                            heterochromatin assembly 41
                              inactivation of X chromosome by heterochromatin assembly 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.