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ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway involved in dorsal/ventral neural tube patterning
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Accession:GO:0060831 term browser browse the term
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.
Synonyms:exact_synonym: hedgehog signaling pathway involved in dorsal/ventral neural tube patterning;   hh signaling pathway involved in dorsal/ventral neural tube patterning;   smoothened signalling pathway involved in dorsal/ventral neural tube patterning


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smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Ift122 intraflagellar transport 122 JBrowse link 4 147,756,574 147,826,983 RGD:1624291
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
G Tbc1d32 TBC1 domain family, member 32 JBrowse link 20 37,463,879 37,701,268 RGD:1624291
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
G Wdr19 WD repeat domain 19 JBrowse link 14 44,705,012 44,767,120 RGD:1624291
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk20 cyclin-dependent kinase 20 JBrowse link 17 1,935,900 1,942,867 RGD:1624291
G Gpr161 G protein-coupled receptor 161 JBrowse link 13 83,530,389 83,576,117 RGD:1624291
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1624291
RGD:1600115
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:1624291
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
G Traf3ip1 TRAF3 interacting protein 1 JBrowse link 9 98,621,499 98,658,223 RGD:1624291
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gorab golgin, RAB6-interacting JBrowse link 13 81,682,207 81,698,827 RGD:1624291
regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk20 cyclin-dependent kinase 20 JBrowse link 17 1,935,900 1,942,867 RGD:1624291
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19676
    signaling 7531
      signal transduction 6946
        cell surface receptor signaling pathway 2759
          smoothened signaling pathway 160
            smoothened signaling pathway involved in dorsal/ventral neural tube patterning 15
              negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 7
              positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1
              regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 11
Path 2
Term Annotations click to browse term
  biological_process 19676
    developmental process 6727
      anatomical structure development 6175
        multicellular organism development 5632
          embryo development 1264
            embryo development ending in birth or egg hatching 824
              chordate embryonic development 806
                neural tube development 196
                  neural tube patterning 49
                    dorsal/ventral neural tube patterning 31
                      smoothened signaling pathway involved in dorsal/ventral neural tube patterning 15
                        negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 7
                        positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1
                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.