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ONTOLOGY REPORT - ANNOTATIONS


Term:lymphatic endothelial cell differentiation
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Accession:GO:0060836 term browser browse the term
Definition:The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.


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lymphatic endothelial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B ISO
IEA
(MGI:MGI:4436974|PMID:19903896)
GO_REF:0000107
RGD
Ensembl
PMID:19903896 GO_REF:0000107, MGI:MGI:4436974 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746
JBrowse link
G Acvrl1 activin A receptor like type 1 ISO (PMID:19903896)
(MGI:MGI:4436974|PMID:19903896)
RGD PMID:19903896 MGI:MGI:4436974 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO (MGI:MGI:4436974|PMID:19903896) RGD PMID:19903896 MGI:MGI:4436974 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Prox1 prospero homeobox 1 ISO (PMID:12198161)
MGI:MGI:2182767|MGI:MGI:3609548 (MGI:MGI:3820329|PMID:19056883)
RGD PMID:12198161, PMID:19056883 MGI:MGI:3820329 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
G Sox18 SRY-box transcription factor 18 ISO MGI:MGI:2178809 (MGI:MGI:3828192|PMID:18931657) RGD PMID:18931657 MGI:MGI:3828192 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127
JBrowse link
lymphatic endothelial cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdpn podoplanin ISO
ISS
(MGI:MGI:4453945|PMID:20110424)
GO_REF:0000024
RGD
UniProt
PMID:20110424 GO_REF:0000024, MGI:MGI:4453945 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
regulation of transcription involved in lymphatic endothelial cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 ISO (PMID:18815287) RGD PMID:18815287 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473
JBrowse link
G Prox1 prospero homeobox 1 ISO (PMID:18815287) RGD PMID:18815287 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        lymph vessel development 29
          lymphatic endothelial cell differentiation 7
            lymphatic endothelial cell fate commitment + 3
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            circulatory system development 1224
              vasculature development 772
                lymph vessel development 29
                  lymphatic endothelial cell differentiation 7
                    lymphatic endothelial cell fate commitment + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.