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ONTOLOGY REPORT - ANNOTATIONS


Term:establishment of blood-brain barrier
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Accession:GO:0060856 term browser browse the term
Definition:Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
Synonyms:exact_synonym: establishment of BBB


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establishment of blood-brain barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:8657330
G Lsr lipolysis stimulated lipoprotein receptor JBrowse link 1 89,383,515 89,399,041 RGD:1624291
RGD:1600115
G Mfsd2a major facilitator superfamily domain containing 2A JBrowse link 5 140,642,865 140,657,759 RGD:1624291
RGD:1600115
central nervous system vasculogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
RGD:1600115
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1600115
RGD:1624291
G Wnt7a Wnt family member 7A JBrowse link 4 122,994,425 123,040,609 RGD:1624291
RGD:1600115
G Wnt7b Wnt family member 7B JBrowse link 7 126,423,418 126,465,724 RGD:1624291
establishment of endothelial blood-brain barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:1598561
G Cldn3 claudin 3 JBrowse link 12 21,831,341 21,832,813 RGD:1624291
RGD:1600115
establishment of glial blood-brain barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
RGD:1600115
G Mxra8 matrix remodeling associated 8 JBrowse link 5 173,288,200 173,292,926 RGD:1600115
RGD:1624291
negative regulation of establishment of blood-brain barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:2317116
G Ttpa alpha tocopherol transfer protein JBrowse link 5 34,007,926 34,029,315 RGD:1624291
RGD:1600115
regulation of establishment of blood-brain barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adgra2 adhesion G protein-coupled receptor A2 JBrowse link 16 69,094,587 69,133,015 RGD:1600115
RGD:1624291
G Reck reversion-inducing-cysteine-rich protein with kazal motifs JBrowse link 5 59,348,568 59,415,169 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    developmental process 6647
      anatomical structure development 6113
        cell development 2477
          establishment of blood-brain barrier 16
            establishment of endothelial blood-brain barrier + 7
            establishment of glial blood-brain barrier 2
            negative regulation of establishment of blood-brain barrier 2
            positive regulation of establishment of blood-brain barrier 0
            regulation of establishment of blood-brain barrier + 4
Path 2
Term Annotations click to browse term
  biological_process 19317
    developmental process 6647
      cellular developmental process 4428
        cell differentiation 4205
          cell development 2477
            establishment of blood-brain barrier 16
              establishment of endothelial blood-brain barrier + 7
              establishment of glial blood-brain barrier 2
              negative regulation of establishment of blood-brain barrier 2
              positive regulation of establishment of blood-brain barrier 0
              regulation of establishment of blood-brain barrier + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.