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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac muscle cell fate commitment
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Accession:GO:0060923 term browser browse the term
Definition:The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
Synonyms:exact_synonym: cardiomyocyte cell fate commitment;   heart muscle cell fate commitment


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cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:1624291
RGD:1600115
G RGD1311744 similar to RIKEN cDNA 5830475I06 JBrowse link 8 43,315,104 43,336,357 RGD:1600115
G Tbx3 T-box transcription factor 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
atrioventricular node cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
G Wnt8a Wnt family member 8A JBrowse link 18 27,331,236 27,336,829 RGD:1624291
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cellular process 17240
      cellular developmental process 4415
        cell fate commitment 285
          cardiac cell fate commitment 14
            cardiac muscle cell fate commitment 9
              atrial cardiac muscle cell fate commitment 0
              canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment + 4
              cardiac muscle cell fate determination 0
              cardiac pacemaker cell fate commitment + 1
              ventricular cardiac muscle cell fate commitment 0
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            circulatory system development 1201
              heart development 682
                cardiac muscle tissue development 257
                  cardiac muscle cell differentiation 146
                    cardiac muscle cell fate commitment 9
                      atrial cardiac muscle cell fate commitment 0
                      canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment + 4
                      cardiac muscle cell fate determination 0
                      cardiac pacemaker cell fate commitment + 1
                      ventricular cardiac muscle cell fate commitment 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.