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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial to mesenchymal transition involved in cardiac fibroblast development
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Accession:GO:0060940 term browser browse the term
Definition:A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.


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epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdcd4 programmed cell death 4 JBrowse link 1 274,616,625 274,648,204 RGD:10400865
G Spry1 sprouty RTK signaling antagonist 1 JBrowse link 2 124,400,689 124,405,331 RGD:10400865

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18179
    developmental process 6551
      anatomical structure morphogenesis 2778
        animal organ morphogenesis 1117
          heart morphogenesis 279
            cardiac epithelial to mesenchymal transition 37
              epithelial to mesenchymal transition involved in cardiac fibroblast development 2
Path 2
Term Annotations click to browse term
  biological_process 18179
    developmental process 6551
      anatomical structure development 6031
        multicellular organism development 5511
          system development 5062
            circulatory system development 1188
              heart development 681
                cardiocyte differentiation 183
                  cardiac fibroblast cell differentiation 3
                    cardiac fibroblast cell development 3
                      epicardium-derived cardiac fibroblast cell development 3
                        epithelial to mesenchymal transition involved in cardiac fibroblast development 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.