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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of gene silencing by RNA
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Accession:GO:0060967 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.


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negative regulation of gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnd1 DND microRNA-mediated repression inhibitor 1 ISO
IBA
(PMID:18155131)
PMID:21873635
RGD PMID:18155131, PMID:21873635 RGD:13792537 NCBI chr18:29,608,588...29,611,212
Ensembl chr18:29,608,588...29,611,212
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 ISS
ISO
GO_REF:0000024
RNAcentral:URS000024463E_9606 (PMID:26595526), (PMID:27089893)
UniProt
RGD
PMID:26595526, PMID:27089893 GO_REF:0000024 NCBI chr12:2,461,502...2,502,432
Ensembl chr12:2,461,502...2,502,432
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:19409607) RGD PMID:19409607 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO (PMID:28522568) RGD PMID:28522568 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase ISO
IBA
ISS
(PMID:23063121)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23063121, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:141,132,106...141,136,700
Ensembl chr 7:141,132,133...141,136,700
JBrowse link
G Lin28b lin-28 homolog B ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:50,482,536...50,580,273
Ensembl chr20:50,486,809...50,564,987
JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 ISO UniProtKB:P40763 (PMID:31507089) RGD PMID:31507089 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lin28b lin-28 homolog B ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:50,482,536...50,580,273
Ensembl chr20:50,486,809...50,564,987
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO (PMID:31507089) RGD PMID:31507089 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 ISO (PMID:20388878) RGD PMID:20388878 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO (MGI:MGI:5562625|PMID:24161931) RGD PMID:24161931 MGI:MGI:5562625 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:31124343), (PMID:31824476) RGD PMID:31124343, PMID:31824476 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 ISO MGI:MGI:1890508 (MGI:MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:MGI:5013521 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Zc3h10 zinc finger CCCH type containing 10 ISO (PMID:28431233) RGD PMID:28431233 NCBI chr 7:2,968,428...2,972,521
Ensembl chr 7:2,968,435...2,972,521
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A ISO
ISS
(PMID:22055188)
GO_REF:0000024
RGD
UniProt
PMID:22055188 GO_REF:0000024 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 ISO MGI:MGI:2180033|MGI:MGI:98834 (MGI:MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:MGI:5013521 NCBI chr 5:139,982,404...140,015,541
Ensembl chr 5:139,983,680...140,015,541
JBrowse link
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tert telomerase reverse transcriptase ISO (PMID:19701182) RGD PMID:19701182 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
negative regulation of RNA interference term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific ISO
IEA
(MGI:MGI:3573853|PMID:15556947)
GO_REF:0000107
RGD
Ensembl
PMID:15556947 GO_REF:0000107, MGI:MGI:3573853 NCBI chr 2:189,045,551...189,085,448
Ensembl chr 2:189,062,443...189,083,236
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      gene silencing 256
        gene silencing by RNA 153
          negative regulation of gene silencing by RNA 21
            negative regulation of RNA interference + 2
            negative regulation of gene silencing by miRNA + 19
            negative regulation of small RNA loading onto RISC 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      organic substance metabolic process 11651
        macromolecule metabolic process 10086
          gene expression 6304
            regulation of gene expression 4813
              negative regulation of gene expression 2169
                gene silencing 256
                  gene silencing by RNA 153
                    regulation of gene silencing by RNA 53
                      negative regulation of gene silencing by RNA 21
                        negative regulation of RNA interference + 2
                        negative regulation of gene silencing by miRNA + 19
                        negative regulation of small RNA loading onto RISC 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.