ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of gene silencing
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Accession:GO:0060968 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.


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regulation of gene silencing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:1600115
RGD:1624291
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 JBrowse link 17 43,814,773 43,815,183 RGD:1624291
G Hist1h3a histone cluster 1 H3 family member A JBrowse link 17 43,616,206 43,616,735 RGD:1624291
G Hist1h3b histone cluster 1, H3b JBrowse link 17 44,760,023 44,764,058 RGD:1624291
G LOC684819 similar to H3 histone, family 2 isoform 2 JBrowse link 17 43,794,397 43,795,493 RGD:1624291
negative regulation of chromatin silencing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad2 ATPase family, AAA domain containing 2 JBrowse link 7 97,984,754 98,027,379 RGD:13792537
G Atad2b ATPase family, AAA domain containing 2B JBrowse link 6 28,998,080 29,066,850 RGD:13792537
G H1f0 H1 histone family, member 0 JBrowse link 7 120,260,776 120,262,636 RGD:13792537
G H1fnt H1 histone family, member N, testis-specific JBrowse link 7 139,871,491 139,872,858 RGD:13792537
G H1foo H1 histone family, member O, oocyte-specific JBrowse link 4 147,844,658 147,849,779 RGD:13792537
G H1fx H1 histone family, member X JBrowse link 4 119,889,016 119,892,661 RGD:13792537
G Hils1 histone linker H1 domain, spermatid-specific 1 JBrowse link 10 82,775,691 82,776,487 RGD:13792537
G Hist1h1a histone cluster 1 H1 family member a JBrowse link 17 43,614,101 43,614,844 RGD:13792537
G Hist1h1b histone cluster 1 H1 family member b JBrowse link 17 44,766,313 44,766,981 RGD:13792537
G Hist1h1c histone cluster 1 H1 family member c JBrowse link 17 43,638,938 43,640,445 RGD:13792537
G Hist1h1d histone cluster 1 H1 family member d JBrowse link 17 43,797,711 43,798,450 RGD:13792537
G Hist1h1e histone cluster 1 H1 family member e JBrowse link 17 43,734,461 43,735,120 RGD:13792537
G Hist1h1t histone cluster 1 H1 family member t JBrowse link 17 43,675,190 43,675,934 RGD:13792537
negative regulation of chromatin silencing at rDNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Phf2 PHD finger protein 2 JBrowse link 17 16,240,458 16,274,626 RGD:1624291
RGD:1600115
G Phf8 PHD finger protein 8 JBrowse link X 21,063,487 21,168,750 RGD:1624291
negative regulation of gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnd1 DND microRNA-mediated repression inhibitor 1 JBrowse link 18 29,608,588 29,611,212 RGD:1624291
RGD:13792537
G Elavl1 ELAV like RNA binding protein 1 JBrowse link 12 2,461,502 2,502,432 RGD:1600115
RGD:1624291
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
negative regulation of methylation-dependent chromatin silencing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 4 155,359,909 155,371,104 RGD:1624291
RGD:1600115
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 JBrowse link 4 155,386,367 155,414,034 RGD:1624291
RGD:1600115
G Tet1 tet methylcytosine dioxygenase 1 JBrowse link 20 27,359,122 27,438,039 RGD:1624291
RGD:1600115
negative regulation of pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcdin3d BCDIN3 domain containing RNA methyltransferase JBrowse link 7 141,132,106 141,136,700 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:12789709
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:1624291
RGD:1600115
G Ncor2 nuclear receptor co-repressor 2 JBrowse link 12 36,871,917 37,033,701 RGD:1624291
RGD:1600115
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
RGD:1600115
G Zc3h10 zinc finger CCCH type containing 10 JBrowse link 7 2,968,428 2,972,521 RGD:1624291
RGD:1600115
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:1624291
RGD:1600115
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:1624291
RGD:1600115
negative regulation of RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 2 189,045,551 189,085,448 RGD:1624291
RGD:1600115
positive regulation of chromatin silencing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mier1 MIER1 transcriptional regulator JBrowse link 5 122,642,065 122,693,642 RGD:1624291
RGD:1600115
G Sin3a SIN3 transcription regulator family member A JBrowse link 8 61,748,590 61,803,314 RGD:1624291
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
positive regulation of chromatin silencing at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:1624291
RGD:1600115
positive regulation of gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ajuba ajuba LIM protein JBrowse link 15 33,208,210 33,218,456 RGD:1624291
RGD:13792537
RGD:1600115
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
RGD:1600115
G Fmr1 fragile X mental retardation 1 JBrowse link X 154,684,924 154,722,369 RGD:1600115
RGD:1624291
G Fxr1 FMR1 autosomal homolog 1 JBrowse link 2 120,529,716 120,570,356 RGD:1624291
RGD:1600115
G Limd1 LIM domains containing 1 JBrowse link 8 132,553,218 132,598,826 RGD:1624291
RGD:13792537
RGD:1600115
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:10400879
G Pum1 pumilio RNA-binding family member 1 JBrowse link 5 148,781,239 148,911,776 RGD:1624291
RGD:1600115
G Pum2 pumilio RNA-binding family member 2 JBrowse link 6 33,786,184 33,865,693 RGD:1624291
RGD:1600115
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:1624291
RGD:1600115
G Trim71 tripartite motif containing 71 JBrowse link 8 122,553,015 122,604,787 RGD:1624291
RGD:1600115
G Wtip WT1 interacting protein JBrowse link 1 89,966,496 89,999,892 RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
positive regulation of methylation-dependent chromatin silencing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf7ip activating transcription factor 7 interacting protein JBrowse link 4 170,476,998 170,563,063 RGD:1600115
RGD:1624291
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:1600115
RGD:1624291
G Morc2 MORC family CW-type zinc finger 2 JBrowse link 14 83,889,138 83,930,263 RGD:1624291
RGD:1600115
G Mphosph8 M-phase phosphoprotein 8 JBrowse link 15 36,918,843 36,946,712 RGD:1600115
RGD:1624291
G Pphln1 periphilin 1 JBrowse link 7 134,602,109 134,693,807 RGD:1600115
RGD:1624291
G Resf1 retroelement silencing factor 1 JBrowse link 4 183,879,177 183,905,807 RGD:1624291
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 JBrowse link 2 196,495,867 196,527,412 RGD:1600115
RGD:1624291
G Tasor transcription activation suppressor JBrowse link 16 3,050,506 3,108,168 RGD:1624291
RGD:1600115
G Trim28 tripartite motif-containing 28 JBrowse link 1 65,544,369 65,551,043 RGD:1624291
RGD:1600115
positive regulation of miRNA mediated inhibition of translation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1600115
RGD:1624291
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 JBrowse link 11 83,907,659 83,927,683 RGD:1624291
RGD:1600115
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Ddx5 DEAD-box helicase 5 JBrowse link 10 94,979,759 94,988,461 RGD:1624291
RGD:1600115
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
RGD:1600115
G Lin28a lin-28 homolog A JBrowse link 5 152,230,343 152,247,873 RGD:1624291
RGD:1600115
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1624291
RGD:1600115
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:1624291
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 JBrowse link 2 5,569,954 5,579,894 RGD:1624291
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1600115
RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
positive regulation of RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Xpo5 exportin 5 JBrowse link 9 17,125,201 17,163,170 RGD:1624291
RGD:1600115
regulation of chromatin silencing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hira histone cell cycle regulator JBrowse link 11 86,168,196 86,276,430 RGD:13792537
G LOC100911837 protein HIRA-like JBrowse link 11 85,802,536 85,896,680 RGD:13792537
G Uty ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome JBrowse link Y 1,065,274 1,206,127 RGD:1624291
regulation of chromatin silencing at rDNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H2afy H2A histone family, member Y JBrowse link 17 9,282,109 9,344,698 RGD:1624291
G Naa40 N(alpha)-acetyltransferase 40, NatD catalytic subunit JBrowse link 1 222,478,021 222,495,382 RGD:13792537
regulation of chromatin silencing at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc45 cell division cycle 45 JBrowse link 11 86,328,785 86,354,099 RGD:13792537
regulation of gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fmr1 fragile X mental retardation 1 JBrowse link X 154,684,924 154,722,369 RGD:1624291
RGD:1600115
G Lin28a lin-28 homolog A JBrowse link 5 152,230,343 152,247,873 RGD:1624291
G Mael maelstrom spermatogenic transposon silencer JBrowse link 13 84,412,569 84,452,140 RGD:1600115
G Mir154 microRNA 154 JBrowse link 6 133,888,586 133,888,669 RGD:1624291
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link 10 106,698,359 106,763,639 RGD:1624291
G Trim71 tripartite motif containing 71 JBrowse link 8 122,553,015 122,604,787 RGD:1600115
RGD:1624291
regulation of methylation-dependent chromatin silencing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link 7 144,121,688 144,126,860 RGD:1624291
RGD:1600115
regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link 7 144,121,688 144,126,860 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17928
    cellular process 16079
      gene silencing 229
        regulation of gene silencing 86
          negative regulation of gene silencing + 35
          regulation of chromatin silencing + 38
          regulation of gene silencing by RNA + 44
          regulation of posttranscriptional gene silencing + 44
Path 2
Term Annotations click to browse term
  biological_process 17928
    metabolic process 10678
      organic substance metabolic process 10129
        macromolecule metabolic process 8687
          regulation of macromolecule metabolic process 5660
            negative regulation of macromolecule metabolic process 2647
              negative regulation of gene expression 1749
                gene silencing 229
                  regulation of gene silencing 86
                    negative regulation of gene silencing + 35
                    regulation of chromatin silencing + 38
                    regulation of gene silencing by RNA + 44
                    regulation of posttranscriptional gene silencing + 44
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.