ONTOLOGY REPORT - ANNOTATIONS


Term:dendritic spine morphogenesis
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Accession:GO:0060997 term browser browse the term
Definition:The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.


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dendritic spine morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:1624291
RGD:1600115
G Ctnnd2 catenin delta 2 JBrowse link 2 83,227,247 84,094,315 RGD:1600115
RGD:13792537
RGD:1624291
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:8554095
RGD:1600115
RGD:1624291
G Dock10 dedicator of cytokinesis 10 JBrowse link 9
9
86,424,638
86,312,470
86,571,854
86,423,054
RGD:1624291
G Dvl1 dishevelled segment polarity protein 1 JBrowse link 5 173,295,948 173,308,014 RGD:10449514
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:8554330
G Ephb1 Eph receptor B1 JBrowse link 8 110,376,954 110,813,193 RGD:1600115
RGD:1624291
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:1624291
RGD:1600115
G Ephb3 Eph receptor B3 JBrowse link 11 83,527,960 83,546,742 RGD:1624291
RGD:1600115
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:1624291
G Myo5b myosin Vb JBrowse link 18 70,426,865 70,729,985 RGD:11533643
G Pak3 p21 (RAC1) activated kinase 3 JBrowse link X 114,784,452 115,042,683 RGD:1624291
RGD:1600115
G Prmt3 protein arginine methyltransferase 3 JBrowse link 1 105,113,595 105,200,253 RGD:9491824
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Sept7 septin 7 JBrowse link 8 26,412,910 26,476,615 RGD:1624291
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:1624291
RGD:13792537
RGD:1600115
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:13792537
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1600115
RGD:13792537
RGD:1624291
G Wasl WASP like actin nucleation promoting factor JBrowse link 4 51,677,722 51,726,212 RGD:1600115
RGD:1624291
G Wnt7a Wnt family member 7A JBrowse link 4 122,994,425 123,040,609 RGD:1624291
RGD:1600115
G Zfp365 zinc finger protein 365 JBrowse link 20 22,060,160 22,083,766 RGD:1624291
RGD:1600115
negative regulation of dendritic spine morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnm3 dynamin 3 JBrowse link 13 79,906,711 80,379,967 RGD:8553820
G Dtnbp1 dystrobrevin binding protein 1 JBrowse link 17 20,090,136 20,182,332 RGD:11251757
G Efna1 ephrin A1 JBrowse link 2 188,588,808 188,596,156 RGD:1624291
RGD:1600115
G Ngef neuronal guanine nucleotide exchange factor JBrowse link 9 94,569,286 94,601,852 RGD:1624291
RGD:1600115
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Ube3a ubiquitin protein ligase E3A JBrowse link 1 116,586,901 116,678,161 RGD:11079590
positive regulation of dendritic spine morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actr2 actin related protein 2 JBrowse link 14 104,338,486 104,375,840 RGD:11530033
G Actr3 actin related protein 3 JBrowse link 13 41,695,520 41,738,622 RGD:11530033
G Afdn afadin, adherens junction formation factor JBrowse link 1 53,713,873 53,861,918 RGD:13838731
G Baiap2 BAI1-associated protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:9684988
G Bhlhb9 basic helix-loop-helix family member B9 JBrowse link X 106,359,981 106,393,457 RGD:1624291
RGD:1600115
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:8553829
G Caprin1 cell cycle associated protein 1 JBrowse link 3 93,701,830 93,789,580 RGD:1600115
RGD:1624291
G Caprin2 caprin family member 2 JBrowse link 4 183,304,993 183,374,195 RGD:1624291
G Cask calcium/calmodulin dependent serine protein kinase JBrowse link X 9,815,652 10,156,155 RGD:11576294
G Cux2 cut-like homeobox 2 JBrowse link 12 40,016,774 40,221,067 RGD:1624291
RGD:1600115
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10398809
RGD:1624291
RGD:1600115
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:13792545
G Dnm1l dynamin 1-like JBrowse link 11 88,830,968 88,882,271 RGD:7800727
G Eef2k eukaryotic elongation factor-2 kinase JBrowse link 1 190,780,211 190,839,926 RGD:10401235
G Itpka inositol-trisphosphate 3-kinase A JBrowse link 3 111,545,007 111,553,605 RGD:8553536
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:1624291
G Lrp8 LDL receptor related protein 8 JBrowse link 5 127,404,348 127,476,636 RGD:1624291
G Marcks myristoylated alanine rich protein kinase C substrate JBrowse link 20 42,966,140 42,971,838 RGD:9685333
G Mfn1 mitofusin 1 JBrowse link 2 118,929,738 118,971,689 RGD:7800727
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:7800727
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:7800727
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 JBrowse link 10 61,456,144 61,577,412 RGD:1624291
RGD:1600115
G Pak3 p21 (RAC1) activated kinase 3 JBrowse link X 114,784,452 115,042,683 RGD:7775053
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1600115
RGD:1624291
G Stau2 staufen double-stranded RNA binding protein 2 JBrowse link 5 2,257,910 2,497,429 RGD:10043163
G Tiam1 T-cell lymphoma invasion and metastasis 1 JBrowse link 11 29,931,083 30,061,173 RGD:10043325
regulation of dendritic spine morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abi2 abl-interactor 2 JBrowse link 9 67,234,612 67,284,504 RGD:1624291
G Adam10 ADAM metallopeptidase domain 10 JBrowse link 8 77,107,355 77,237,483 RGD:13703034
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:13210528
G Arhgap33 Rho GTPase activating protein 33 JBrowse link 1 88,977,460 88,990,780 RGD:13508596
G Arhgap44 Rho GTPase activating protein 44 JBrowse link 10 51,501,547 51,669,546 RGD:1600115
RGD:13792537
RGD:1624291
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:1624291
RGD:1600115
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 JBrowse link 10 67,862,054 67,863,255 RGD:1624291
RGD:1600115
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:1624291
RGD:1600115
G Dnm3 dynamin 3 JBrowse link 13 79,906,711 80,379,967 RGD:8554738
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:1624291
RGD:1600115
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:13792537
RGD:1600115
G Lzts3 leucine zipper tumor suppressor family member 3 JBrowse link 3 123,174,444 123,185,649 RGD:13210540
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:8553412
RGD:1600115
G Pdlim5 PDZ and LIM domain 5 JBrowse link 2 247,815,214 247,989,198 RGD:8554803
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A JBrowse link 4 29,976,485 30,247,371 RGD:10043779
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1624291
RGD:7349315
RGD:1600115
G Sipa1l1 signal-induced proliferation-associated 1 like 1 JBrowse link 6 106,052,212 106,163,249 RGD:8554032
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link 10 85,460,059 85,517,671 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    developmental process 6339
      anatomical structure development 5946
        dendritic spine development 122
          dendritic spine morphogenesis 68
            negative regulation of dendritic spine morphogenesis 8
            positive regulation of dendritic spine morphogenesis 26
            regulation of dendritic spine morphogenesis + 50
Path 2
Term Annotations click to browse term
  biological_process 17926
    developmental process 6339
      anatomical structure development 5946
        multicellular organism development 5440
          system development 5021
            nervous system development 2551
              neurogenesis 1839
                generation of neurons 1708
                  neuron differentiation 1539
                    neuron development 1251
                      neuron projection development 1105
                        dendrite development 301
                          dendrite morphogenesis 180
                            dendritic spine morphogenesis 68
                              negative regulation of dendritic spine morphogenesis 8
                              positive regulation of dendritic spine morphogenesis 26
                              regulation of dendritic spine morphogenesis + 50
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.