Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of dendritic spine development
go back to main search page
Accession:GO:0060999 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.


show annotations for term's descendants           Sort by:
 
positive regulation of dendritic spine development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E ISO
IEA
(PMID:24328732)
GO_REF:0000107
RGD
Ensembl
PMID:24328732 GO_REF:0000107 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arf1 ADP-ribosylation factor 1 IMP RGD PMID:23889934 RGD:8553918 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I ISO
ISS
(PMID:18184567)
GO_REF:0000024
RGD
UniProt
PMID:18184567 GO_REF:0000024 NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177
JBrowse link
G Cdkl5 cyclin-dependent kinase-like 5 IMP RGD PMID:23671101 RGD:12791021 NCBI chr  X:35,536,396...35,773,204
Ensembl chr  X:35,599,258...35,771,711
JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:25723479 RGD:11570400 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 ISO (MGI:5300629|PMID:22153079) RGD PMID:22153079 MGI:5300629 NCBI chr 1:255,660,165...255,842,671
Ensembl chr 1:255,665,238...255,815,733
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 ISO (MGI:5608921|PMID:25232112) RGD PMID:25232112 MGI:5608921 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 IMP RGD PMID:22514323 RGD:10755512 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
JBrowse link
G Fmr1 FMRP translational regulator 1 ISS
ISO
GO_REF:0000024
(MGI:3798322|PMID:18539120)
UniProt
RGD
PMID:18539120 GO_REF:0000024, MGI:3798322 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Foxo6 forkhead box O6 ISO (MGI:5461238|PMID:23222102) RGD PMID:23222102 MGI:5461238 NCBI chr 5:139,208,153...139,227,288
Ensembl chr 5:139,208,046...139,227,196
JBrowse link
G Grn granulin precursor IMP RGD PMID:21813674 RGD:5509044 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K IMP RGD PMID:24990929 RGD:10002784 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
G Il2 interleukin 2 IDA RGD PMID:20225203 RGD:5147914 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Itsn1 intersectin 1 IMP RGD PMID:19258322 RGD:13461864 NCBI chr11:31,943,119...32,069,249
Ensembl chr11:31,893,489...32,069,249
JBrowse link
G Kalrn kalirin, RhoGEF kinase ISO MGI:3831288|MGI:3831292|MGI:97845 (MGI:3821420|PMID:19020030), (MGI:5645427|PMID:25865668) RGD PMID:19020030, PMID:25865668 MGI:3821420, MGI:5645427 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Llph LLP homolog, long-term synaptic facilitation factor ISO (MGI:5796065|PMID:26961175) RGD PMID:26961175 MGI:5796065 NCBI chr 7:65,004,544...65,009,509
Ensembl chr 7:65,005,791...65,008,823
JBrowse link
G LOC103690160 SH3 and multiple ankyrin repeat domains protein 2-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:215,208,591...215,246,638
Ensembl chr 1:215,214,853...215,241,723
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 IDA RGD PMID:16638019 RGD:2317707 NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 ISO MGI:1333110 (MGI:5430253|PMID:22508986) RGD PMID:22508986 MGI:5430253 NCBI chr 8:82,328,013...82,351,108
Ensembl chr 8:82,328,020...82,351,108
JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 ISO MGI:1354946|MGI:2680287 (MGI:5430253|PMID:22508986) RGD PMID:22508986 MGI:5430253 NCBI chr12:40,510,378...40,529,332
Ensembl chr12:40,510,378...40,529,338
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24188180 RGD:12789443 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21683721 RGD:10040994 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 ISO (MGI:5300629|PMID:22153079) RGD PMID:22153079 MGI:5300629 NCBI chr 1:266,953,006...267,038,879
Ensembl chr 1:266,952,561...267,038,883
JBrowse link
G Nlgn1 neuroligin 1 IDA
ISO
IMP
PMID:17582332
(MGI:5493186|PMID:23143522)
UniProtKB:Q99K10 (PMID:23143522)
RGD PMID:23143522, PMID:17582332, PMID:15681343 MGI:5493186, RGD:8553502, RGD:8553420 NCBI chr 2:111,057,291...111,973,681
Ensembl chr 2:111,057,291...111,793,326
JBrowse link
G Nlgn2 neuroligin 2 IMP RGD PMID:15681343 RGD:8553420 NCBI chr10:56,431,586...56,444,847
Ensembl chr10:56,431,573...56,444,847
JBrowse link
G Nlgn3 neuroligin 3 IMP RGD PMID:15681343 RGD:8553420 NCBI chr  X:71,199,390...71,227,460
Ensembl chr  X:71,199,491...71,222,732
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22509272 RGD:7174739 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrg1 neuregulin 1 ISO MGI:1928831 (MGI:3803029|PMID:18596162), (MGI:4461331|PMID:20610754) RGD PMID:18596162, PMID:20610754 MGI:3803029, MGI:4461331 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Palm paralemmin ISO (MGI:5009384|PMID:18287537) RGD PMID:18287537 MGI:5009384 NCBI chr 7:12,708,024...12,721,055
Ensembl chr 7:12,708,015...12,793,711
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:12052877 RGD:1299363 NCBI chr 4:29,976,485...30,247,371
Ensembl chr 4:29,978,739...30,241,911
JBrowse link
G Psen1 presenilin 1 ISO (PMID:21951279) RGD PMID:21951279 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Rac1 Rac family small GTPase 1 ISO MGI:2685385 (MGI:5645427|PMID:25865668) RGD PMID:25865668 MGI:5645427 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G RGD1563888 similar to DNA segment, Chr 16, ERATO Doi 472, expressed ISO (MGI:5908509|PMID:27404227) RGD PMID:27404227 MGI:5908509 NCBI chr11:17,073,296...17,120,235
Ensembl chr11:17,076,980...17,130,120
JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 IDA
IBA
PMID:18287537
PMID:21873635
UniProt
GO_Central
PMID:18287537, PMID:21873635 RGD:8553517, RGD:13792537 NCBI chr 1:100,297,137...100,344,377
Ensembl chr 1:100,297,152...100,344,377
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 ISS
ISO
IEA
IBA
PMID:21795692
(MGI:5320264|PMID:21795692)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:21795692, PMID:21795692, PMID:21873635 GO_REF:0000107, MGI:5320264, RGD:7349315, RGD:13792537 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:16595860 RGD:11568665 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 IMP RGD PMID:24117785 RGD:8554267 NCBI chr 3:162,480,766...162,594,145
Ensembl chr 3:162,480,804...162,581,610
JBrowse link
positive regulation of dendritic spine morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 IMP RGD PMID:23441206 RGD:11530033 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Actr3 actin related protein 3 IMP RGD PMID:23441206 RGD:11530033 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658
JBrowse link
G Afdn afadin, adherens junction formation factor IMP RGD PMID:22948147 RGD:13838731 NCBI chr 1:53,713,873...53,861,918
Ensembl chr 1:53,715,693...53,802,658
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 IMP RGD PMID:15673667 RGD:9684988 NCBI chr10:109,107,326...109,187,458
Ensembl chr10:109,107,389...109,187,115
JBrowse link
G Bhlhb9 basic helix-loop-helix family member B9 ISO (MGI:5545985|PMID:21199326) RGD PMID:21199326 MGI:5545985 NCBI chr  X:106,359,981...106,393,457
Ensembl chr  X:106,390,759...106,393,459
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta IMP PMID:12873385 UniProt PMID:12873385 RGD:8553829 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Caprin1 cell cycle associated protein 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:4888105|PMID:20516077)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20516077 GO_REF:0000024, GO_REF:0000107, MGI:4888105 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Caprin2 caprin family member 2 ISO (MGI:4888105|PMID:20516077) RGD PMID:20516077 MGI:4888105 NCBI chr 4:183,304,993...183,374,195
Ensembl chr 4:183,305,813...183,374,195
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase IMP RGD PMID:18606847 RGD:11576294 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155
JBrowse link
G Cux2 cut-like homeobox 2 ISO (MGI:4836115|PMID:20510857) RGD PMID:20510857 MGI:4836115 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Dbn1 drebrin 1 IMP
ISO
IBA
IEA
ISS
(MGI:5688247|PMID:25865831)
PMID:21873635
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:25865831, PMID:19174472, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:5688247, RGD:10398809, RGD:13792537 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dbnl drebrin-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:86,029,335...86,044,364
Ensembl chr14:86,029,335...86,044,364
JBrowse link
G Dhx36 DEAH-box helicase 36 IMP PMID:23651854 UniProt PMID:23651854 RGD:13792545 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Dnm1l dynamin 1-like IMP RGD PMID:19605646 RGD:7800727 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase IMP RGD PMID:20427644 RGD:10401235 NCBI chr 1:190,780,211...190,839,926
Ensembl chr 1:190,780,236...190,842,324
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A IMP PMID:19890013 MGI PMID:19890013 RGD:8553536 NCBI chr 3:111,545,007...111,553,605
Ensembl chr 3:111,545,007...111,553,604
JBrowse link
G Kalrn kalirin, RhoGEF kinase ISO MGI:4358076 (MGI:4355773|PMID:19625617) RGD PMID:19625617 MGI:4355773 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Lrp8 LDL receptor related protein 8 ISO (MGI:5426130|PMID:21852430) RGD PMID:21852430 MGI:5426130 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate IMP RGD PMID:16202710 RGD:9685333 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Mfn1 mitofusin 1 IMP RGD PMID:19605646 RGD:7800727 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:19605646 RGD:7800727 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IMP RGD PMID:19605646 RGD:7800727 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 ISO (MGI:5619436|PMID:23483716) RGD PMID:23483716 MGI:5619436 NCBI chr10:61,456,144...61,577,412
Ensembl chr10:61,456,145...61,577,412
JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 IMP RGD PMID:18481281 RGD:7775053 NCBI chr  X:114,784,452...115,042,683
Ensembl chr  X:114,929,029...115,036,669
JBrowse link
G Reln reelin IEA
ISO
GO_REF:0000107
(MGI:5286805|PMID:21664258), (MGI:5426130|PMID:21852430)
Ensembl
RGD
PMID:21664258, PMID:21852430 GO_REF:0000107, MGI:5286805, MGI:5426130 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Stau2 staufen double-stranded RNA binding protein 2 IMP RGD PMID:16418534 RGD:10043163 NCBI chr 5:2,257,910...2,497,429 JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IMP RGD PMID:16474385 RGD:10043325 NCBI chr11:29,931,083...30,061,173
Ensembl chr11:29,933,163...30,051,103
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      positive regulation of developmental process 1475
        positive regulation of dendritic spine development 64
          positive regulation of dendritic spine morphogenesis 27
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            nervous system development 2719
              neurogenesis 1936
                generation of neurons 1780
                  neuron differentiation 1614
                    neuron development 1323
                      neuron projection development 1164
                        dendrite development 316
                          dendritic spine development 128
                            regulation of dendritic spine development 83
                              positive regulation of dendritic spine development 64
                                positive regulation of dendritic spine morphogenesis 27
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.