ONTOLOGY REPORT - ANNOTATIONS


Term:hepaticobiliary system development
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Accession:GO:0061008 term browser browse the term
Definition:The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.
Synonyms:exact_synonym: hepatobiliary system development


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common bile duct development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1624291
RGD:1600115
G Sox17 SRY box 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
RGD:1600115
determination of liver left/right asymmetry term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccdc39 coiled-coil domain containing 39 JBrowse link 2 120,278,605 120,367,829 RGD:1624291
G Ccdc40 coiled-coil domain containing 40 JBrowse link 10 108,055,270 108,393,408 RGD:1624291
G Dnaaf1 dynein, axonemal, assembly factor 1 JBrowse link 19 52,217,427 52,245,930 RGD:1624291
RGD:1600115
G Nphp3 nephrocystin 3 JBrowse link 8 112,526,553 112,575,745 RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
RGD:1600115
G Zic3 Zic family member 3 JBrowse link X 140,875,191 140,888,344 RGD:1624291
RGD:1600115
gall bladder development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Nipbl NIPBL, cohesin loading factor JBrowse link 2 57,508,830 57,676,197 RGD:1624291
RGD:1600115
G Sox17 SRY box 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
RGD:1600115
hepatic duct development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
hepatoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
RGD:1600115
hepatocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:2306909
RGD:13792537
G Cps1 carbamoyl-phosphate synthase 1 JBrowse link 9 74,113,437 74,236,274 RGD:4144098
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:2306655
G E2f7 E2F transcription factor 7 JBrowse link 7 53,275,659 53,318,261 RGD:1624291
RGD:1600115
G E2f8 E2F transcription factor 8 JBrowse link 1 104,185,436 104,203,683 RGD:1600115
RGD:1624291
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:2312718
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:12904750
RGD:1600115
G Hnf4g hepatocyte nuclear factor 4, gamma JBrowse link 2 100,225,880 100,372,710 RGD:1600115
G Itga2 integrin subunit alpha 2 JBrowse link 2 46,996,904 47,097,011 RGD:2307397
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:13792537
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
RGD:1600115
G Taf10 TATA-box binding protein associated factor 10 JBrowse link 1 170,585,160 170,586,428 RGD:1624291
RGD:1600115
G Wnt1 Wnt family member 1 JBrowse link 7 140,464,999 140,469,046 RGD:2326223
hepatocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:10047310
RGD:1624291
G Fgl1 fibrinogen-like 1 JBrowse link 16 54,153,086 54,188,120 RGD:1600115
RGD:1624291
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:1624291
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1624291
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
RGD:1600115
G Rps6ka1 ribosomal protein S6 kinase A1 JBrowse link 5 152,078,217 152,122,684 RGD:1624291
RGD:1600115
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:10047310
RGD:1624291
intrahepatic bile duct development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gak cyclin G associated kinase JBrowse link 14 2,100,104 2,174,332 RGD:1624291
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1624291
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
liver development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aacs acetoacetyl-CoA synthetase JBrowse link 12 36,512,393 36,555,694 RGD:2301023
G Acadm acyl-CoA dehydrogenase medium chain JBrowse link 2 260,124,418 260,148,589 RGD:1624291
RGD:1600115
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:2326169
G Acat2 acetyl-CoA acetyltransferase 2 JBrowse link 1 47,972,399 47,992,654 RGD:2326169
G Aco1 aconitase 1 JBrowse link 5 56,425,076 56,481,218 RGD:11552585
G Aco2 aconitase 2 JBrowse link 7 123,102,493 123,145,608 RGD:11552585
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
RGD:1600115
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:8548535
G Afp alpha-fetoprotein JBrowse link 14 19,141,755 19,159,919 RGD:2292045
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Ak2 adenylate kinase 2 JBrowse link 5 147,185,474 147,204,050 RGD:5490208
G Ak3 adenylate kinase 3 JBrowse link 1 247,144,486 247,169,690 RGD:5490208
G Ak4 adenylate kinase 4 JBrowse link 5 120,250,318 120,309,153 RGD:632174
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:1643117
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:1643117
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:2300311
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 JBrowse link 13 85,580,828 85,597,497 RGD:2313411
G Aldob aldolase, fructose-bisphosphate B JBrowse link 5 64,805,772 64,818,813 RGD:2313428
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325721
G Arf6 ADP-ribosylation factor 6 JBrowse link 6 91,697,109 91,698,257 RGD:1624291
RGD:1600115
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4144072
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:1599266
RGD:1599268
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:2316008
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:1599266
RGD:4139912
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:1624291
G Atp5f1b ATP synthase F1 subunit beta JBrowse link 7 2,504,708 2,511,748 RGD:13792579
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:11341669
G Baat bile acid CoA:amino acid N-acyltransferase JBrowse link 5 64,768,397 64,777,368 RGD:69770
G Bdh1 3-hydroxybutyrate dehydrogenase 1 JBrowse link 11 72,577,547 72,619,435 RGD:4105456
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link 6 26,657,507 26,680,459 RGD:2303538
G Cadm1 cell adhesion molecule 1 JBrowse link 8 51,858,906 52,200,591 RGD:2289097
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:5683869
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1582338
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:1582338
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:1582338
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:7248763
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:1625368
RGD:1624291
RGD:1600115
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:69946
G Cebpg CCAAT/enhancer binding protein gamma JBrowse link 1 91,286,956 91,297,459 RGD:69946
G Cfc1 cripto, FRL-1, cryptic family 1 JBrowse link 9 41,045,352 41,051,979 RGD:1624291
G Chek1_v2 checkpoint kinase 1, variant 2 RGD:70230
G Cit citron rho-interacting serine/threonine kinase JBrowse link 12 46,334,669 46,494,152 RGD:628497
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 1 12,823,363 12,825,806 RGD:1624291
RGD:1600115
G Cobl cordon-bleu WH2 repeat protein JBrowse link 14 92,341,949 92,497,169 RGD:1624291
RGD:1600115
G Cp ceruloplasmin JBrowse link 2 104,744,249 104,803,034 RGD:728241
G Cps1 carbamoyl-phosphate synthase 1 JBrowse link 9 74,113,437 74,236,274 RGD:4144072
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1599633
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:727721
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 JBrowse link 7 123,634,400 123,638,757 RGD:2301678
G Dbp D-box binding PAR bZIP transcription factor JBrowse link 1 101,687,896 101,692,845 RGD:727680
G Ddx39b DExD-box helicase 39B JBrowse link 20 4,806,103 4,818,600 RGD:632224
G Dut deoxyuridine triphosphatase JBrowse link 3 117,514,399 117,525,450 RGD:5133681
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:2289959
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:13204733
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:1581923
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:4889418
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2289959
G Foxm1 forkhead box M1 JBrowse link 4 161,685,236 161,697,633 RGD:1624291
G Fpgs folylpolyglutamate synthase JBrowse link 3 11,717,667 11,729,694 RGD:2315102
G Fscn1 fascin actin-bundling protein 1 JBrowse link 12 13,655,459 13,668,595 RGD:2317768
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 JBrowse link 15 19,721,292 19,734,032 RGD:2302171
G H19 H19, imprinted maternally expressed transcript (non-protein coding) JBrowse link 1 215,744,404 215,747,080 RGD:1342456
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:1624291
RGD:1600115
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Hlx H2.0-like homeobox JBrowse link 13 102,637,967 102,643,376 RGD:1624291
RGD:1600115
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase JBrowse link 5 154,294,841 154,308,582 RGD:2326149
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 JBrowse link 2 52,427,351 52,445,082 RGD:2326169
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:2326125
G Hnf1a HNF1 homeobox A JBrowse link 12 47,407,811 47,433,342 RGD:1624291
RGD:1600115
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
RGD:1600115
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:10042969
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:10002779
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:1625368
G Icmt isoprenylcysteine carboxyl methyltransferase JBrowse link 5 169,475,270 169,482,031 RGD:1624291
G Ift88 intraflagellar transport 88 JBrowse link 15 37,690,417 37,786,855 RGD:1624291
G Igf2r insulin-like growth factor 2 receptor JBrowse link 1 48,176,095 48,264,482 RGD:2311626
G Jarid2 jumonji and AT-rich interaction domain containing 2 JBrowse link 17 20,183,440 20,365,219 RGD:1624291
RGD:1600115
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:1624291
RGD:1600115
G Klf1 Kruppel like factor 1 JBrowse link 19 26,016,289 26,019,557 RGD:1624291
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:11060153
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:9685195
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2307448
G Lsr lipolysis stimulated lipoprotein receptor JBrowse link 1 89,383,515 89,399,041 RGD:1624291
RGD:1600115
G Man2a1 mannosidase, alpha, class 2A, member 1 JBrowse link 9 112,293,388 112,451,677 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:2317549
RGD:13792537
RGD:1624291
G Mpst mercaptopyruvate sulfurtransferase JBrowse link 7 119,626,636 119,631,317 RGD:9685558
G Mrtfb myocardin related transcription factor B JBrowse link 10 1,151,163 1,273,269 RGD:1624291
G Nat1 N-acetyltransferase 1 JBrowse link 16 23,970,742 23,991,573 RGD:2303764
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1624291
G Nts neurotensin JBrowse link 7 44,111,594 44,120,998 RGD:9743870
G Onecut1 one cut homeobox 1 JBrowse link 8 81,765,779 81,799,894 RGD:1624291
RGD:1600115
G Onecut2 one cut homeobox 2 JBrowse link 18 59,830,375 59,882,490 RGD:1624291
G Otc ornithine carbamoyltransferase JBrowse link X 13,524,804 13,601,074 RGD:4144072
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:629554
RGD:1624291
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
RGD:1600115
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:1624291
G Pkd1 polycystin 1, transient receptor potential channel interacting JBrowse link 10 13,914,057 13,962,008 RGD:1624291
RGD:1600115
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:2303137
G Prkcsh protein kinase C substrate 80K-H JBrowse link 8 23,014,802 23,026,507 RGD:1624291
RGD:1600115
G Proc protein C, inactivator of coagulation factors Va and VIIIa JBrowse link 18 24,918,402 24,928,822 RGD:1299299
RGD:1624291
G Pros1 protein S JBrowse link 7 1,206,648 1,288,140 RGD:1299299
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:5133274
RGD:1624291
G Psmb9 proteasome subunit beta 9 JBrowse link 20 3,973,424 3,978,845 RGD:9854625
G Ptcd2 pentatricopeptide repeat domain 2 JBrowse link 2 29,570,581 29,598,328 RGD:1624291
RGD:1600115
G Ptn pleiotrophin JBrowse link 4 64,239,156 64,330,996 RGD:727382
G Qdpr quinoid dihydropteridine reductase JBrowse link 14 70,164,682 70,178,284 RGD:5128606
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:2314298
RGD:13792537
G Rarb retinoic acid receptor, beta JBrowse link 15 9,915,223 10,262,599 RGD:13792537
G Rb1cc1 RB1-inducible coiled-coil 1 JBrowse link 5 13,033,918 13,097,369 RGD:1624291
RGD:1600115
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:1624291
RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590173
RGD:9590212
G Rhbdd3 rhomboid domain containing 3 JBrowse link 14 85,350,852 85,357,029 RGD:1624291
RGD:1600115
G Rpgrip1l Rpgrip1-like JBrowse link 19 17,115,266 17,208,055 RGD:1624291
RGD:1600115
G Runx1 runt-related transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:1624291
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:1643117
G Sec63 SEC63 homolog, protein translocation regulator JBrowse link 20 47,494,270 47,563,222 RGD:1624291
RGD:1600115
G Slc25a4 solute carrier family 25 member 4 JBrowse link 16 49,266,903 49,270,698 RGD:9681468
G Slco1b2 solute carrier organic anion transporter family, member 1B2 JBrowse link 4 175,814,118 175,881,775 RGD:2303131
G Slco2b1 solute carrier organic anion transporter family, member 2b1 JBrowse link 1 164,623,313 164,671,612 RGD:2316987
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1624291
RGD:1600115
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:1624291
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1624291
RGD:1600115
G Sp1 Sp1 transcription factor JBrowse link 7 144,014,173 144,044,635 RGD:1624291
G Sp3 Sp3 transcription factor JBrowse link 3 59,644,579 59,689,011 RGD:1624291
RGD:1600115
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:4892048
G Srsf5 serine and arginine rich splicing factor 5 JBrowse link 6 104,611,026 104,640,033 RGD:11039429
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:2291935
G Taf10 TATA-box binding protein associated factor 10 JBrowse link 1 170,585,160 170,586,428 RGD:1624291
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:1624291
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:2314319
G Thra_v1 thyroid hormone receptor alpha, variant 1 RGD:2314319
G Thra_v2 thyroid hormone receptor alpha, variant 2 RGD:2314319
G Tk1 thymidine kinase 1 JBrowse link 10 106,817,556 106,828,888 RGD:2317236
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:2315453
RGD:2317023
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:2317023
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 JBrowse link 9 95,256,628 95,302,822 RGD:2317023
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 JBrowse link 9 95,241,609 95,302,822 RGD:2317023
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C JBrowse link 9 95,233,957 95,302,822 RGD:2317023
G Upb1 beta-ureidopropionase 1 JBrowse link 20 14,167,383 14,193,724 RGD:2317093
G Upf2 UPF2, regulator of nonsense mediated mRNA decay JBrowse link 17 76,176,379 76,287,246 RGD:1624291
G Urod uroporphyrinogen decarboxylase JBrowse link 5 135,855,429 135,859,515 RGD:4145103
G Vwf von Willebrand factor JBrowse link 4 158,085,059 158,219,525 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:1600115
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:1624291
RGD:1600115
liver morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cul3 cullin 3 JBrowse link 9 86,044,485 86,129,066 RGD:1624291
RGD:1600115
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1624291
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link 2 238,719,389 238,802,975 RGD:1624291
liver regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:8548508
G Alas2 5'-aminolevulinate synthase 2 JBrowse link X 23,167,576 23,187,356 RGD:11035238
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:704403
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 JBrowse link 10 59,528,849 59,560,440 RGD:13782137
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:1600115
RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:11531107
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Cftr cystic fibrosis transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11567227
G Cldn1 claudin 1 JBrowse link 11 77,815,216 77,830,373 RGD:11344894
G Cpb2 carboxypeptidase B2 JBrowse link 15 57,290,849 57,339,762 RGD:7243112
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:11565141
G Csnk2a2 casein kinase 2 alpha 2 JBrowse link 19 9,972,537 10,012,043 RGD:11565141
G Csnk2b casein kinase 2 beta JBrowse link 20 5,108,692 5,113,675 RGD:11565141
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:10395295
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit JBrowse link 10 89,104,026 89,139,978 RGD:1624291
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:1624291
RGD:1600115
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:8662889
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:728788
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:10402121
G Gfer growth factor, augmenter of liver regeneration JBrowse link 10 14,059,347 14,061,703 RGD:9685725
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
RGD:12911223
RGD:12832760
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:12911223
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:8694419
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:8694419
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:10755743
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 JBrowse link 1 199,248,084 199,251,745 RGD:1599972
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:12911223
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11049526
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 JBrowse link 4 140,247,297 140,580,749 RGD:13793384
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:7297052
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:10059623
G Ncl nucleolin JBrowse link 9 93,369,119 93,377,643 RGD:9686389
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:10413865
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:11534994
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:10448980
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 14 113,530,470 113,561,645 RGD:11554175
G Pou2f1 POU class 2 homeobox 1 JBrowse link 13 84,075,316 84,217,368 RGD:9743904
G Prmt1 protein arginine methyltransferase 1 JBrowse link 1 100,971,132 100,980,411 RGD:2299961
G Prmt5 protein arginine methyltransferase 5 JBrowse link 15 33,156,508 33,165,893 RGD:2299961
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:12911223
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 JBrowse link 5 74,248,996 74,368,167 RGD:1599982
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:10003155
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:9850085
G Reg1a regenerating family member 1 alpha JBrowse link 4 109,497,962 109,500,626 RGD:10044030
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590197
G Rpl10 ribosomal protein L10 JBrowse link X 156,438,251 156,440,461 RGD:11038709
G Rpl13 ribosomal protein L13 JBrowse link 19 55,917,489 55,920,040 RGD:11038709
G Rpl18 ribosomal protein L18 JBrowse link 1 101,700,910 101,703,551 RGD:11038709
G Rpl19 ribosomal protein L19 JBrowse link 10 85,978,691 85,981,979 RGD:11038709
G Rpl30 ribosomal protein L30 JBrowse link 7 73,213,538 73,216,431 RGD:11038709
G Rpl32 ribosomal protein L32 JBrowse link 4 147,715,480 147,719,044 RGD:11038709
G Rpl7 ribosomal protein L7 JBrowse link 5 2,633,517 2,636,525 RGD:11038709
G Rps15 ribosomal protein S15 JBrowse link 7 12,282,134 12,283,573 RGD:11040696
G Rps16 ribosomal protein S16 JBrowse link 1 85,405,499 85,408,444 RGD:11038709
G Rps24 ribosomal protein S24 JBrowse link 16 757,390 762,091 RGD:11041663
G Serpina10 serpin family A member 10 JBrowse link 6 127,500,014 127,508,470 RGD:729731
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:12832760
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:9685423
G Srsf5 serine and arginine rich splicing factor 5 JBrowse link 6 104,611,026 104,640,033 RGD:729792
G Sulf2 sulfatase 2 JBrowse link 3 162,791,349 162,872,984 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:11073669
G Tyms thymidylate synthetase JBrowse link 9 121,918,875 121,931,564 RGD:2317422
G Ucp2 uncoupling protein 2 JBrowse link 1 165,506,375 165,512,744 RGD:7204431
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:10003090
G Vwf von Willebrand factor JBrowse link 4 158,085,059 158,219,525 RGD:727737
G Wdr35 WD repeat domain 35 JBrowse link 6 34,094,291 34,152,048 RGD:11553927
negative regulation of hepatocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Frzb frizzled-related protein JBrowse link 3 67,635,604 67,668,772 RGD:1624291
RGD:1600115
negative regulation of hepatocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:11252157
G Ceacam1 carcinoembryonic antigen related cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:11059592
RGD:1600115
RGD:1624291
G Cpb2 carboxypeptidase B2 JBrowse link 15 57,290,849 57,339,762 RGD:7243112
G Lims1 LIM zinc finger domain containing 1 JBrowse link 20 27,895,981 28,004,767 RGD:1624291
G Lims2 LIM zinc finger domain containing 2 JBrowse link 18 24,707,951 24,746,159 RGD:1624291
RGD:1600115
positive regulation of hepatocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:8885195
G Foxa3 forkhead box A3 JBrowse link 1 79,921,292 79,930,219 RGD:2315086
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115
positive regulation of hepatocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:11341689
G Hpn hepsin JBrowse link 1 89,534,112 89,549,575 RGD:1600115
RGD:1624291
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 JBrowse link 4 140,247,297 140,580,749 RGD:13793384
G Mdk midkine JBrowse link 3 80,841,003 80,843,895 RGD:1600115
RGD:1624291
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Ptn pleiotrophin JBrowse link 4 64,239,156 64,330,996 RGD:9834996
RGD:1624291
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1600115
RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
RGD:1600115
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
RGD:1600115
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:1600115
regulation of hepatocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
RGD:1600115
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8142374
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6484147
G Sulf2 sulfatase 2 JBrowse link 3 162,791,349 162,872,984 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    multicellular organismal process 8524
      multicellular organism development 5425
        system development 5004
          hepaticobiliary system development 252
            common bile duct development + 8
            gall bladder development 3
            liver development + 249
Path 2
Term Annotations click to browse term
  biological_process 17896
    developmental process 6323
      anatomical structure development 5930
        multicellular organism development 5425
          system development 5004
            hepaticobiliary system development 252
              common bile duct development + 8
              gall bladder development 3
              liver development + 249
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.