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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of protein tyrosine kinase activity
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Accession:GO:0061097 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.


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regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Rap2b RAP2B, member of RAS oncogene family JBrowse link 2 151,685,251 151,685,802 RGD:1624291
RGD:1600115
G Rap2c RAP2C, member of RAS oncogene family JBrowse link X 138,224,039 138,237,157 RGD:1624291
negative regulation of brain-derived neurotrophic factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam72a family with sequence similarity 72, member A JBrowse link 13 48,288,071 48,298,604 RGD:8553945
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:13792537
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:13792537
G Cblc Cbl proto-oncogene C JBrowse link 1 80,699,321 80,716,146 RGD:1624291
RGD:13792537
G Chmp6 charged multivesicular body protein 6 JBrowse link 10 109,073,678 109,079,348 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:8553726
RGD:1600115
RGD:1624291
G Gprc5a G protein-coupled receptor, class C, group 5, member A JBrowse link 4 168,832,937 168,851,650 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
G Socs4 suppressor of cytokine signaling 4 JBrowse link 15 24,056,383 24,070,868 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1624291
G Vps25 vacuolar protein sorting 25 homolog JBrowse link 10 89,174,684 89,180,165 RGD:1624291
G Zfyve28 zinc finger FYVE-type containing 28 JBrowse link 14 81,725,513 81,811,142 RGD:1624291
RGD:13792537
G Zgpat zinc finger CCCH-type and G-patch domain containing JBrowse link 3 176,865,078 176,881,603 RGD:1624291
RGD:1600115
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:1624291
negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:1600115
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:13792537
RGD:1600115
G Cep43 centrosomal protein 43 JBrowse link 1 53,122,330 53,152,872 RGD:1600115
G Ggnbp2 gametogenetin binding protein 2 JBrowse link 10 72,156,729 72,188,834 RGD:1624291
RGD:1600115
G Hyal2 hyaluronidase 2 JBrowse link 8 116,324,062 116,328,978 RGD:1600115
RGD:1624291
G Ibtk inhibitor of Bruton tyrosine kinase JBrowse link 8 93,323,454 93,397,044 RGD:1600115
G Mvp major vault protein JBrowse link 1 198,420,813 198,448,612 RGD:1600115
RGD:1624291
G Ptk6 protein tyrosine kinase 6 JBrowse link 3 176,698,305 176,706,896 RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1600115
G Sh3bp5 SH3-domain binding protein 5 JBrowse link 16 7,473,367 7,559,976 RGD:13792537
G Sh3bp5l SH3 binding domain protein 5 like JBrowse link 10 43,768,620 43,785,702 RGD:13792537
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link 10 85,460,059 85,517,671 RGD:1624291
RGD:1600115
G Thy1 Thy-1 cell surface antigen JBrowse link 8 48,382,121 48,387,271 RGD:12793046
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:1624291
RGD:1600115
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:2317913
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:1624291
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1624291
G Epgn epithelial mitogen JBrowse link 14 18,627,103 18,635,135 RGD:1624291
RGD:1600115
G Ereg epiregulin JBrowse link 14 18,577,620 18,591,395 RGD:632743
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:1624291
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:1624291
G Neurl1 neuralized E3 ubiquitin protein ligase 1 JBrowse link 1 266,953,006 267,038,879 RGD:1624291
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:1624291
RGD:1600115
positive regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:1624291
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1624291
positive regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abi1 abl-interactor 1 JBrowse link 17 89,951,662 90,033,334 RGD:1600115
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:1624291
RGD:1600115
G Afap1l2 actin filament associated protein 1-like 2 JBrowse link 1 277,730,760 277,827,299 RGD:1600115
G Agrn agrin JBrowse link 5 173,589,910 173,622,813 RGD:1624291
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:1624291
G Alkal1 ALK and LTK ligand 1 JBrowse link 5 12,896,136 12,925,571 RGD:1600115
G Alkal2 ALK and LTK ligand 2 JBrowse link 6 49,824,725 49,834,921 RGD:1600115
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Cass4 Cas scaffold protein family member 4 JBrowse link 3 170,398,496 170,438,381 RGD:1624291
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:1600115
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1600115
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:1600115
RGD:1624291
G Dlg3 discs large MAGUK scaffold protein 3 JBrowse link X 70,596,246 70,648,529 RGD:13506268
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:13506268
G Dok7 docking protein 7 JBrowse link 14 80,925,409 80,963,454 RGD:1624291
G Dvl2 dishevelled segment polarity protein 2 JBrowse link 10 56,609,810 56,619,269 RGD:1624291
G Efna1 ephrin A1 JBrowse link 2 188,588,808 188,596,156 RGD:1624291
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1624291
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:1624291
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:1624291
RGD:1600115
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:1600115
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1624291
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1624291
RGD:1600115
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1600115
G Gprc5b G protein-coupled receptor, class C, group 5, member B JBrowse link 1 188,688,743 188,713,724 RGD:1624291
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:1600115
RGD:8553716
RGD:1624291
G Hsph1 heat shock protein family H (Hsp110) member 1 JBrowse link 12 6,322,685 6,341,898 RGD:1624291
G Lilra5 leukocyte immunoglobulin like receptor A5 JBrowse link 1 73,655,767 73,682,232 RGD:1624291
G LOC100910732 serine/threonine-protein kinase PAK 2-like JBrowse link 11 71,959,058 72,021,252 RGD:1600115
G Lrp8 LDL receptor related protein 8 JBrowse link 5 127,404,348 127,476,636 RGD:1624291
G Ncapg2 non-SMC condensin II complex, subunit G2 JBrowse link 6 144,291,313 144,362,454 RGD:1624291
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 JBrowse link 17 22,984,792 23,179,701 RGD:1624291
G Nox4 NADPH oxidase 4 JBrowse link 1 150,796,359 150,976,186 RGD:1624291
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1600115
G Pak2 p21 (RAC1) activated kinase 2 JBrowse link 11 72,829,407 72,865,815 RGD:1600115
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1600115
RGD:1624291
G Prnp prion protein JBrowse link 3 124,515,917 124,531,320 RGD:1624291
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1624291
RGD:1600115
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link 10 85,460,059 85,517,671 RGD:1624291
RGD:1600115
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor JBrowse link 5 133,864,401 133,878,604 RGD:1624291
G Tcf3 transcription factor 3 JBrowse link 7 12,146,642 12,168,400 RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
G Unc119 unc-119 lipid binding chaperone JBrowse link 10 65,606,919 65,612,324 RGD:1624291
RGD:13792537
G Vldlr very low density lipoprotein receptor JBrowse link 1 245,236,819 245,273,688 RGD:1600115
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplp2 amyloid beta precursor like protein 2 JBrowse link 8 32,298,526 32,328,821 RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
RGD:1600115
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    biological regulation 13336
      regulation of molecular function 3020
        regulation of catalytic activity 2300
          regulation of transferase activity 981
            regulation of kinase activity 868
              regulation of protein kinase activity 758
                regulation of protein tyrosine kinase activity 92
                  negative regulation of protein tyrosine kinase activity + 31
                  positive regulation of protein tyrosine kinase activity + 58
                  regulation of brain-derived neurotrophic factor-activated receptor activity + 1
                  regulation of epidermal growth factor-activated receptor activity + 26
                  regulation of non-membrane spanning protein tyrosine kinase activity + 3
Path 2
Term Annotations click to browse term
  biological_process 19334
    metabolic process 11555
      organic substance metabolic process 10949
        macromolecule metabolic process 9418
          protein metabolic process 5973
            protein modification process 3851
              cellular protein modification process 3851
                peptidyl-amino acid modification 1272
                  peptidyl-tyrosine modification 390
                    peptidyl-tyrosine phosphorylation 387
                      regulation of peptidyl-tyrosine phosphorylation 276
                        regulation of protein tyrosine kinase activity 92
                          negative regulation of protein tyrosine kinase activity + 31
                          positive regulation of protein tyrosine kinase activity + 58
                          regulation of brain-derived neurotrophic factor-activated receptor activity + 1
                          regulation of epidermal growth factor-activated receptor activity + 26
                          regulation of non-membrane spanning protein tyrosine kinase activity + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.