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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein tyrosine kinase activity
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Accession:GO:0061099 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


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negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV1 caveolin 1 JBrowse link 7 121,193,678 121,229,655 RGD:9068941
G CEP43 centrosomal protein 43 JBrowse link 6 169,945,218 169,988,027 RGD:9068941
G GGNBP2 gametogenetin binding protein 2 JBrowse link 17 20,786,936 20,831,761 RGD:9068941
G HYAL2 hyaluronidase 2 JBrowse link 3 51,479,020 51,484,638 RGD:9068941
G IBTK inhibitor of Bruton tyrosine kinase JBrowse link 6 83,325,428 83,402,670 RGD:9068941
G MVP major vault protein JBrowse link 16 30,190,929 30,217,971 RGD:9068941
G PTK6 protein tyrosine kinase 6 JBrowse link 20 61,453,386 61,462,951 RGD:9068941
G PTPN2 protein tyrosine phosphatase non-receptor type 2 JBrowse link 18 16,562,044 16,659,570 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G RACK1 receptor for activated C kinase 1 JBrowse link 5 183,712,665 183,720,128 RGD:9068941
G SH3BP5 SH3 domain binding protein 5 JBrowse link 3 15,517,447 15,594,971 RGD:9068941
G SH3BP5L SH3 binding domain protein 5 like RGD:9068941
G SRCIN1 SRC kinase signaling inhibitor 1 JBrowse link 17 18,942,084 19,015,753 RGD:9068941
G THY1 Thy-1 cell surface antigen JBrowse link 11 118,180,717 118,186,901 RGD:9068941
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBL Cbl proto-oncogene JBrowse link 11 117,973,187 118,076,459 RGD:9068941
G CBLB Cbl proto-oncogene B JBrowse link 3 109,690,120 109,905,306 RGD:9068941
G CBLC Cbl proto-oncogene C JBrowse link 19 50,331,257 50,353,865 RGD:9068941
G CHMP6 charged multivesicular body protein 6 JBrowse link 17 81,145,786 81,151,962 RGD:9068941
G ERRFI1 ERBB receptor feedback inhibitor 1 JBrowse link 1 8,019,048 8,033,674 RGD:9068941
G GPRC5A G protein-coupled receptor class C group 5 member A JBrowse link 12 13,282,865 13,309,963 RGD:9068941
G PSEN1 presenilin 1 JBrowse link 14 72,579,024 72,663,876 RGD:9068941
G SNX6 sorting nexin 6 JBrowse link 14 33,511,019 33,576,699 RGD:9068941
G SOCS4 suppressor of cytokine signaling 4 JBrowse link 14 53,890,043 53,911,227 RGD:9068941
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2A 47,745,216 47,808,566 RGD:9068941
G TSG101 tumor susceptibility 101 JBrowse link 11 18,201,381 18,248,149 RGD:9068941
G VPS25 vacuolar protein sorting 25 homolog JBrowse link 17 14,763,523 14,769,672 RGD:9068941
G ZFYVE28 zinc finger FYVE-type containing 28 JBrowse link 4 2,320,446 2,470,638 RGD:9068941
G ZGPAT zinc finger CCCH-type and G-patch domain containing JBrowse link 20 61,630,274 61,662,967 RGD:9068941
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DUSP22 dual specificity phosphatase 22 JBrowse link 6 242,121 301,248 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15679
    metabolic process 10517
      negative regulation of metabolic process 2902
        negative regulation of cellular metabolic process 2467
          negative regulation of cellular protein metabolic process 998
            negative regulation of protein modification process 585
              negative regulation of protein phosphorylation 394
                negative regulation of protein kinase activity 222
                  negative regulation of protein tyrosine kinase activity 29
                    negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                    negative regulation of epidermal growth factor-activated receptor activity 14
                    negative regulation of non-membrane spanning protein tyrosine kinase activity 1
Path 2
Term Annotations click to browse term
  biological_process 15679
    metabolic process 10517
      organic substance metabolic process 10000
        macromolecule metabolic process 8610
          protein metabolic process 5466
            protein modification process 3952
              cellular protein modification process 3952
                peptidyl-amino acid modification 1210
                  peptidyl-tyrosine modification 361
                    peptidyl-tyrosine phosphorylation 358
                      regulation of peptidyl-tyrosine phosphorylation 245
                        negative regulation of peptidyl-tyrosine phosphorylation 50
                          negative regulation of protein tyrosine kinase activity 29
                            negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                            negative regulation of epidermal growth factor-activated receptor activity 14
                            negative regulation of non-membrane spanning protein tyrosine kinase activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.