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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein tyrosine kinase activity
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Accession:GO:0061099 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


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negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1 JBrowse link NW_004955432 22,258,262 22,292,403 RGD:9068941
G Cep43 centrosomal protein 43 JBrowse link NW_004955439 15,029,485 15,059,076 RGD:9068941
G Ggnbp2 gametogenetin binding protein 2 JBrowse link NW_004955451 1,345,720 1,386,100 RGD:9068941
G Hyal2 hyaluronidase 2 JBrowse link NW_004955532 2,120,781 2,125,083 RGD:9068941
G Ibtk inhibitor of Bruton tyrosine kinase JBrowse link NW_004955411 10,052,584 10,132,203 RGD:9068941
G Mvp major vault protein JBrowse link NW_004955493 7,113,194 7,141,944 RGD:9068941
G Ptk6 protein tyrosine kinase 6 JBrowse link NW_004955528 687,996 695,596 RGD:9068941
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 JBrowse link NW_004955402 771,410 846,671 RGD:9068941
G Ptprc protein tyrosine phosphatase receptor type C JBrowse link NW_004955406 35,005,577 35,127,395 RGD:9068941
G Rack1 receptor for activated C kinase 1 JBrowse link NW_004955530 78,488 83,297 RGD:9068941
G Sh3bp5 SH3 domain binding protein 5 JBrowse link NW_004955430 2,251,544 2,266,166 RGD:9068941
G Sh3bp5l SH3 binding domain protein 5 like JBrowse link NW_004955418 29,884,660 29,893,611 RGD:9068941
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link NW_004955451 13,673,613 13,734,639 RGD:9068941
G Thy1 Thy-1 cell surface antigen JBrowse link NW_004955412 20,480,284 20,484,958 RGD:9068941
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link NW_004955412 20,307,011 20,388,539 RGD:9068941
G Cblb Cbl proto-oncogene B JBrowse link NW_004955427 6,601,651 6,812,896 RGD:9068941
G Cblc Cbl proto-oncogene C JBrowse link NW_004955555 1,921,896 1,941,247 RGD:9068941
G Chmp6 charged multivesicular body protein 6 JBrowse link NW_004955506 1,987,710 1,994,731 RGD:9068941
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link NW_004955486 4,941,143 4,955,693 RGD:9068941
G Gprc5a G protein-coupled receptor class C group 5 member A JBrowse link NW_004955413 9,765,564 9,784,847 RGD:9068941
G Psen1 presenilin 1 JBrowse link NW_004955523 2,128,529 2,210,737 RGD:9068941
G Snx6 sorting nexin 6 JBrowse link NW_004955409 26,323,940 26,353,675 RGD:9068941
G Socs4 suppressor of cytokine signaling 4 JBrowse link NW_004955409 8,522,540 8,539,551 RGD:9068941
G Socs5 suppressor of cytokine signaling 5 JBrowse link NW_004955441 13,593,342 13,657,389 RGD:9068941
G Tsg101 tumor susceptibility 101 JBrowse link NW_004955414 33,154,812 33,193,769 RGD:9068941
G Vps25 vacuolar protein sorting 25 homolog JBrowse link NW_004955451 16,589,509 16,593,730 RGD:9068941
G Zfyve28 zinc finger FYVE-type containing 28 JBrowse link NW_004955514 1,366,186 1,450,982 RGD:9068941
G Zgpat zinc finger CCCH-type and G-patch domain containing JBrowse link NW_004955528 493,051 519,780 RGD:9068941
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dusp22 dual specificity phosphatase 22 JBrowse link NW_004955465 12,551,063 12,597,386 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14546
    metabolic process 9943
      negative regulation of metabolic process 2803
        negative regulation of cellular metabolic process 2369
          negative regulation of cellular protein metabolic process 952
            negative regulation of protein modification process 577
              negative regulation of protein phosphorylation 392
                negative regulation of protein kinase activity 222
                  negative regulation of protein tyrosine kinase activity 29
                    negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                    negative regulation of epidermal growth factor-activated receptor activity 14
                    negative regulation of non-membrane spanning protein tyrosine kinase activity 1
Path 2
Term Annotations click to browse term
  biological_process 14546
    metabolic process 9943
      organic substance metabolic process 9450
        macromolecule metabolic process 8134
          protein metabolic process 5251
            protein modification process 3828
              cellular protein modification process 3828
                peptidyl-amino acid modification 1183
                  peptidyl-tyrosine modification 359
                    peptidyl-tyrosine phosphorylation 356
                      regulation of peptidyl-tyrosine phosphorylation 241
                        negative regulation of peptidyl-tyrosine phosphorylation 51
                          negative regulation of protein tyrosine kinase activity 29
                            negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                            negative regulation of epidermal growth factor-activated receptor activity 14
                            negative regulation of non-membrane spanning protein tyrosine kinase activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.